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Autor:
Sebastien Folliot, Philippe Moullier, Anna Salvetti, Fabienne Rolling, Robert Morenweiser, Gabrielle Kroner-Lux, Yan Cherel, Pierre Boulanger, Estelle Toublanc, Nicole Brument, Florence Gaden, Véronique Blouin, Isabelle Raimbaud
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 6(5)
Here we describe the development of a two-step chromatography process based on the use of ion-exchange resins for the purification of recombinant adeno-associated virus (rAAV) serotypes-2 and-5. In vitro and in vivo results demonstrate that this meth