Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gabrielle Hawkins"'
Autor:
Yingao Zhang, Yu Huang, Yajie Yin, Yali Fan, Wenchuan Sun, Xiaoling Zhao, Katherine Tucker, Allison Staley, Sarah Paraghamian, Gabrielle Hawkins, Varun Prabhu, Joshua E. Allen, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
ONC206 (Oncoceutics) is an imipiridone with nanomolar potency and analogue of ONC201, a selective dopamine receptor D2 (DRD2) antagonist currently being investigated in phase II clinical trials for serous endometrial cancer (SEC). This study investig
Externí odkaz:
https://doaj.org/article/bb4d20e1f81949ae997b56525b7b27a5
Autor:
Susana García-Recio, Charles M. Perou, Kamila Wisniewska, Victoria L. Bae-Jump, Aatish Thennavan, Venkat S. Malladi, Gabrielle Hawkins, Matthew J. Regner, Joel S. Parker, Raul Mendez-Giraldez, Hector L. Franco
Publikováno v:
Mol Cell
Deconvolution of regulatory mechanisms that drive transcriptional programs in cancer cells is key to understanding tumor biology. Herein, we present matched transcriptome (scRNA-seq) and chromatin accessibility (scATAC-seq) profiles at single-cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23380463fb4b78c181a729199f96657
https://doi.org/10.1016/j.molcel.2021.10.013
https://doi.org/10.1016/j.molcel.2021.10.013
Publikováno v:
Gynecologic Oncology. 162:S130
Objectives: We aimed to identify ethnic differences in genetic mutations associated endometrial cancer (EC), as well as differences in the utilization of sequencing results to direct disease treatment based on actionable mutations among different eth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3276c6f745cc89faec38794b41f9b98c
https://doi.org/10.1016/s0090-8258(21)00889-1
https://doi.org/10.1016/s0090-8258(21)00889-1
Autor:
Chunxiao Zhou, Varun V. Prabhu, Wenchuan Sun, Sarah E. Paraghamian, Gabrielle Hawkins, Victoria L. Bae-Jump, Joshua E. Allen
Publikováno v:
Gynecologic Oncology. 162:S288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::171441a6f1f5e05d6f46474031aae48b
https://doi.org/10.1016/s0090-8258(21)01198-7
https://doi.org/10.1016/s0090-8258(21)01198-7
Publikováno v:
Gynecologic Oncology. 162:S172
Objectives: We aimed to identify clinically-relevant genetic mutations (CRGMs) in ovarian (OV), fallopian tube (FT), primary peritoneal (PP), and endometrial (EC) cancer patients and investigate the impact of targeted therapy (TT). Methods: EMERSE wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2e17211376792b696fa08fab9f98c3e
https://doi.org/10.1016/s0090-8258(21)00969-0
https://doi.org/10.1016/s0090-8258(21)00969-0
Publikováno v:
Gynecologic Oncology. 158:e12-e13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de3a71816554913727149e77835e0e52
https://doi.org/10.1016/j.ygyno.2020.04.029
https://doi.org/10.1016/j.ygyno.2020.04.029
Autor:
Joshua E. Allen, Chunxiao Zhou, Varun V. Prabhu, Victoria L. Bae-Jump, Sarah E. Paraghamian, Yali Fan, Gabrielle Hawkins, Hongyan Suo, Xin Zhang, Wenchuan Sun
Publikováno v:
Clinical Cancer Research. 27:PO044-PO044
Objectives: Poly ADP-ribose polymerase (PARP) inhibitors are effective therapies for patients with homologous recombination (HR) deficient tumors. While HR mutations are rare in endometrial cancers (ECs), emerging data suggests that loss of function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aebba4081785cfc637e0114c4db08e9
https://doi.org/10.1158/1557-3265.endomet20-po044
https://doi.org/10.1158/1557-3265.endomet20-po044
Abstract PR07: Impact of race on the uterine microbiome in women with early stage endometrial cancer
Autor:
Andrew F. Olshan, Temitope O. Keku, Gabrielle Hawkins, Jeffrey Roach, Amber N. McCoy, Victoria L. Bae-Jump, Wendy R. Brewster, Russell Broaddus
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:PR07-PR07
Introduction: African American (AA) women suffer a higher mortality from endometrial cancer (EC) than non-Hispanic white (NHW) women. Potential biological causes for this disparity in AA women include a higher risk of more lethal histologic/molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2a296dc353b25eb491fa9273f25e0d
https://doi.org/10.1158/1538-7755.disp20-pr07
https://doi.org/10.1158/1538-7755.disp20-pr07
Autor:
Joshua E. Allen, Wenchaun Sun, Victoria L. Bae-Jump, Chunxiao Zhou, Sarah E. Paraghamian, Gabrielle Hawkins, Varun V. Prabhu, Yali Fan, Xin Zhang
Publikováno v:
Cancer Research. 80:5336-5336
Objectives: Olaparib is a poly ADP-ribose polymerase inhibitor (PARPi) approved for use as maintenance and treatment in advanced and recurrent ovarian cancer (OC). The imipridone ONC206, a chemical derivative of ONC201, is a bioavailable dopamine rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fedf370765b62731455adc1779fe6e9
https://doi.org/10.1158/1538-7445.am2020-5336
https://doi.org/10.1158/1538-7445.am2020-5336
Autor:
Sarah E. Paraghamian, Chunxiao Zhou, Yali Fan, Joshua E. Allen, Xin Zhang, Victoria L. Bae-Jump, Wenchuan Sun, Varun V. Prabhu, Gabrielle Hawkins, Hongyan Suo
Publikováno v:
Cancer Research. 80:5314-5314
Objectives: Poly ADP-ribose polymerase (PARP) inhibitors are effective therapies for patients with homologous recombination (HR) deficient tumors. While HR mutations are rare in endometrial cancers (ECs), emerging data suggests that loss of function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac3c4d22422ab38ecb42ddc50a635c5
https://doi.org/10.1158/1538-7445.am2020-5314
https://doi.org/10.1158/1538-7445.am2020-5314