Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gabrielle Ghabash"'
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Krabbe disease (KD) is a leukodystrophy caused by mutations in the galactosylceramidase gene. Presymptomatic hematopoietic stem cell transplantation (HSCT) is associated with improved outcomes, but most data are from single-center studies. Our object
Externí odkaz:
https://doaj.org/article/b015126da5714d1aad426af2846253cf
Publikováno v:
J Child Neurol
Objective: The purpose of our study was to understand the healthcare burden and incidence of Krabbe disease (Krabbe). Methods: Retrospective analysis of Krabbe patients identified October 1, 2015 through December 31, 2020, ages birth through age 3, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f3f6e2f8abd3fd2e1ad510417936ac
https://europepmc.org/articles/PMC8671150/
https://europepmc.org/articles/PMC8671150/
Autor:
Maria M. Disotuar, Xiaochun Xiong, Michael C. Lawrence, Danny Hung-Chieh Chou, Rahul Agrawal, Helena Safavi-Hemami, Nicholas A. Smith, Briony E. Forbes, Christopher A. MacRaild, Raymond S. Norton, John Gerbrandt Tasman Menting, Joanna Gajewiak, Xiaomin Wang, Xiao He, Brian J. Smith, Baldomero M. Olivera, Gabrielle Ghabash, Carlie Delaine, Simon J. Fisher
Publikováno v:
Nature structural & molecular biology
Human insulin and its current therapeutic analogs all show propensity, albeit varyingly, to self-associate into dimers and hexamers, which delays their onset of action and makes blood glucose management difficult for people with diabetes. Recently, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412a84f26b3e8ecd41533e3bed8b0925
https://pubmed.ncbi.nlm.nih.gov/32533129
https://pubmed.ncbi.nlm.nih.gov/32533129
Autor:
Yi Wolf Zhang, Prasoona Karra, William L. Holland, Alan Blakely, Christopher P. Hill, Danny Hung-Chieh Chou, Matthew J. Webber, Gabrielle Ghabash, Michael A. VandenBerg, Xiaochun Xiong, Frank G. Whitby
Publikováno v:
Chemical Science
A novel four-disulfide insulin analog was designed with retained bioactivity and increased fibrillation stability.
Although insulin was first purified and used therapeutically almost a century ago, there is still a need to improve therapeutic ef
Although insulin was first purified and used therapeutically almost a century ago, there is still a need to improve therapeutic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d483fee3457833bdc7a1b69601557da
https://pubmed.ncbi.nlm.nih.gov/32110371
https://pubmed.ncbi.nlm.nih.gov/32110371
Autor:
Rahul Agrawal, Xiao He, Brian J. Smith, Danny Hung-Chieh Chou, Raymond S. Norton, John G. Menting, Xiaomin Wang, Briony E. Forbes, Nicholas A. Smith, Joanna Gajewiak, Helena Safavi-Hemami, Michael C. Lawrence, Carlie Delaine, Maria M. Disotuar, Xiaochun Xiong, Christopher A. MacRaild, Simon J. Fisher, Baldomero M. Olivera, Gabrielle Ghabash
Publikováno v:
Nature Structural & Molecular Biology. 27:683-683
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e5f523ef2cc75e81d5cee49814afc74
https://doi.org/10.1038/s41594-020-0460-2
https://doi.org/10.1038/s41594-020-0460-2
Autor:
James A. Nicholls, R. Toby Pennington, Gabrielle Ghabash, David A. Donoso, María José Endara, Kyle G. Dexter, Graham N. Stone, Thomas A. Kursar, Phyllis D. Coley
Publikováno v:
Endara, M-J, Coley, P D, Ghabash, G, Nicholls, J, Dexter, K, Donoso, D A, Stone, G, Pennington, R T & Kursar, T A 2017, ' Coevolutionary arms race versus host defense chase in a tropical herbivore-plant system ', Proceedings of the National Academy of Sciences, vol. 114, no. 36, pp. E7499-E7505 . https://doi.org/10.1073/pnas.1707727114
Coevolutionary models suggest that herbivores drive diversification and community composition in plants. For herbivores, many questions remain regarding how plant defenses shape host choice and community structure. We addressed these questions using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe7bf5b500c08420008d15dd98dee1e
https://doi.org/10.1073/pnas.1707727114
https://doi.org/10.1073/pnas.1707727114