Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Gabrielle G Leblanc"'
Autor:
Hyunsun Park, Robert Hodgson, Gabrielle G Leblanc, Marc Baumann, Anjli Venkateswaran, John Dunlop, Alexander McCampbell, Judith Frydman, Ron R. Kopito, Antti Nurmi, Patrick Sweeney
Publikováno v:
Translational Neurodegeneration
A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity and contribute to cellular proteostatic collapse. Therapeutic options are currently being explored that target different ste
Autor:
Amy R. Brooks-Kayal, Jeffrey L. Noebels, Gabrielle G. Leblanc, Margaret P. Jacobs, Dennis D. Spencer, John W. Swann, Frances E. Jensen, Daniel H. Lowenstein
Publikováno v:
Epilepsy & Behavior. 14:438-445
During the past decade, substantial progress has been made in delineating clinical features of the epilepsies and the basic mechanisms responsible for these disorders. Eleven human epilepsy genes have been identified and many more are now known from
Autor:
Vladimir Hachinski, Costantino Iadecola, Ron C. Petersen, Monique M. Breteler, David L. Nyenhuis, Sandra E. Black, William J. Powers, Charles DeCarli, Jose G. Merino, Raj N. Kalaria, Harry V. Vinters, David M. Holtzman, Gary A. Rosenberg, Anders Wallin, Martin Dichgans, John R. Marler, Gabrielle G. Leblanc
Publikováno v:
Stroke. 37:2220-2241
Background and Purpose— One in 3 individuals will experience a stroke, dementia or both. Moreover, twice as many individuals will have cognitive impairment short of dementia as either stroke or dementia. The commonly used stroke scales do not measu
Publikováno v:
Stroke. 37:248-255
Background and Purpose— This review considers the current state of knowledge of genetic factors underlying vascular cognitive impairment (VCI). Summary of Review— We argue here that genes conferring susceptibility to VCI must be of 2 nonmutually
Publikováno v:
Journal of Neurobiology. 29:249-261
Different anteroposterior (AP) regions of the neural crest normally produce different cell types, both in vivo and in vitro. AP differences in neural crest cell fates appear to be specified in part by mechanisms that act prior to neural crest cell mi
Autor:
Gabrielle G. Leblanc
Publikováno v:
Cell and Tissue Research. 277:97-106
Cranial and trunk neural crest cells developing in vitro differed in their patterns of expression of two major extracellular matrix proteins, fibronectin and collagen I. Cranial neural crest cells showed two distinct phases of fibronectin expression:
Autor:
Gabrielle G. Leblanc
Publikováno v:
Journal of Neurobiology. 21:567-577
This study shows that explants of quail neural crest cultured in a medium containing serum and chick embryo extract give rise to large numbers of cells expressing immunoreactivity for substance P (SP), a neuropeptide found in sensory neurons. These c
Autor:
David Riddell, Barry D. Greenberg, Diana W Shineman, Patrick J. Sweeney, Kimberly Scearce-Levie, Lorenzo M. Refolo, Jennifer L. Bizon, Iva Morse, Beth A. Hollister, Howard Fillit, Guriqbal S. Basi, Carol A. Colton, Feng Luo, Juha Yrjänheikki, Dave Morgan, Gabrielle G Leblanc, John M. Lincecum, Linda Bobbi H Lee
Publikováno v:
Alzheimer's Research & Therapy
Animal models have contributed significantly to our understanding of the underlying biological mechanisms of Alzheimer's disease (AD). As a result, over 300 interventions have been investigated and reported to mitigate pathological phenotypes or impr
Publikováno v:
Developmental biology. 137(2)
Several studies have suggested that the development of cholinergic properties in cranial parasympathetic neurons is determined by these cells' axial level of origin in the neural crest. All cranial parasympathetic neurons normally derive from cranial
Autor:
Costantino Iadecola, Gabrielle G. Leblanc, David L. Nyenhuis, José G. Merino, R. C. Petersen, William J. Powers, Vladimir Hachinski, John R. Marler, Anders Wallin, David M. Holtzman, Charles DeCarli, Sandra E. Black, Harry V. Vinters, Gary A. Rosenberg, Raj N. Kalaria, Martin Dichgans, Monique M.B. Breteler
Publikováno v:
Stroke. 38:1118-1118