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pro vyhledávání: '"Gabrielle Durand"'
The Antidepressant Metapramine is a Low-affinity Antagonist at N -methyl- d -aspartic Acid Receptors
Publikováno v:
Neuropharmacology. 35:1703-1707
Metapramine, a pharmacological compound with antidepressant activity in humans, was tested for possible antiglutamatergic activity, in vitro. We investigated the effects of metapramine on the N-methyl-d-aspartic acid (NMDA) receptor complex, by deter
Autor:
Jean Marie Miquet, Marie-Claude Burgevin, M. Daniel, C. Malgouris, Mireille Meunier, Francoise Bordier, Colette Peny, Gabrielle Durand, Adam Doble, Jean-Charles Blanchard, Alain Boireau, Thierry Chevet, Serge Mignani, Patrick Jimonet
Publikováno v:
European Journal of Pharmacology. 300:237-246
The NMDA antagonist and neuroprotective effects of RPR 104632 (2H-1,2,4-benzothiadiazine-1-dioxide-3-carboxylic acid), a new benzothiadiazine derivative, with affinity for the glycine site of the NMDA receptor-channel complex are described. RPR 10463
Autor:
Gabrielle Durand, Pierre Sedivy, Anne Floch, Daniel Pacot, Claude James, C. Robaut, Daniel Lave, Icilio Cavero, Gérard Le Fur, S. Mondot
Publikováno v:
Biochemical Pharmacology. 36:3221-3229
52770 RP, the N -(3-chlorophenyl)-3-(3-pyridinyl)-1H, 3H-pyrrolo[1,2- c ]thiazole-7-carboxamide, displaces in a potent, specific and competitive manner [ 3 H]PAF from its binding sites on rabbit platelets. Since 52770 RP is not structurally related t