Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Gabrielle, Couchy"'
Autor:
Yana Beulque, Lisa Kinget, Eduard Roussel, Sajedeh Mobaraki, Annouschka Laenen, Philip R. Debruyne, Yannick Van Herck, Marcella Baldewijns, Agnieszka Wozniak, Abhishek D. Garg, Jessica Zucman-Rossi, Gabrielle Couchy, Maarten Albersen, Liesbeth De Wever, Lorenz Haaker, Benoit Beuselinck
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: This study aims to evaluate neutrophil-to-eosinophil ratio (NER) as a prognostic and/or predictive biomarker in metastatic clear cell renal cell carcinoma (m-ccRCC) treated with nivolumab or ipilimumab/nivolumab. Patients/mat
Externí odkaz:
https://doaj.org/article/abbe9ce3cee1430289a9bbcf22379019
Autor:
Annelies Verbiest, Vincent Van Hoef, Cristina Rodriguez-Antona, Jesús García-Donas, Osvaldo Graña-Castro, Maarten Albersen, Marcella Baldewijns, Annouschka Laenen, Eduard Roussel, Patrick Schöffski, Agnieszka Wozniak, Stefano Caruso, Gabrielle Couchy, Jessica Zucman-Rossi, Benoit Beuselinck
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238809 (2020)
Clear-cell renal cell carcinomas (ccRCC) can be divided into four transcriptomic subtypes, two of which have a favorable and two an unfavorable prognosis. To assess mechanisms driving these subtypes, we investigated their miRNA expression patterns. m
Externí odkaz:
https://doaj.org/article/30baa197e6f241efb27d73daebcccfed
Autor:
Quentin Bayard, Léa Meunier, Camille Peneau, Victor Renault, Jayendra Shinde, Jean-Charles Nault, Iadh Mami, Gabrielle Couchy, Giuliana Amaddeo, Emmanuel Tubacher, Delphine Bacq, Vincent Meyer, Tiziana La Bella, Audrey Debaillon-Vesque, Paulette Bioulac-Sage, Olivier Seror, Jean-Frédéric Blanc, Julien Calderaro, Jean-François Deleuze, Sandrine Imbeaud, Jessica Zucman-Rossi, Eric Letouzé
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cyclins A2 and E1 are known to regulate the cell cycle by promoting S phase entry and progression. Here, they identify an aggressive hepatocellular carcinoma subgroup exhibiting cyclin activation through various mechanisms and find this subgroup to d
Externí odkaz:
https://doaj.org/article/d1c71c5d3832437783153fd87d02ea45
Autor:
Eric Letouzé, Jayendra Shinde, Victor Renault, Gabrielle Couchy, Jean-Frédéric Blanc, Emmanuel Tubacher, Quentin Bayard, Delphine Bacq, Vincent Meyer, Jérémy Semhoun, Paulette Bioulac-Sage, Sophie Prévôt, Daniel Azoulay, Valérie Paradis, Sandrine Imbeaud, Jean-François Deleuze, Jessica Zucman-Rossi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Tumorigenesis is a complex process driven by numerous risk factors. Here, genomic analysis of liver cancer reveals the evolution of mutational signatures during tumor development, highlighting mutational and structural signatures linked to environmen
Externí odkaz:
https://doaj.org/article/a2db6282c9e94e1b953a8aca7a20d3f7
Autor:
Jessica Zucman-Rossi, Stéphane Oudard, Aurélien de Reyniès, Catherine Sautès-Fridman, Wolf Herman Fridman, Arnaud Méjean, Jean-Jacques Patard, Corinne Teghom, Reza Elaidi, Mathilde Sibony, Vincent Molinié, Nathalie Rioux-Leclercq, Nicolas Giraldo, Gabrielle Couchy, Virginie Verkarre, Alexandra Karadimou, Etienne Becht, Sylvie Job, Benoit Beuselinck
Supplemental Figure 4-6. Figure S4: Characterisation of the ccRCC molecular subtypes: methylation status and Benporath polycomb signature; Figure S5: Cytogenetic characterization of the ccRCC molecular subtypes; Figure S6: Characterization of the ccR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ef09f55f68b8f227d9be08c1526568
https://doi.org/10.1158/1078-0432.22459043
https://doi.org/10.1158/1078-0432.22459043
Autor:
Jessica Zucman-Rossi, Stéphane Oudard, Aurélien de Reyniès, Catherine Sautès-Fridman, Wolf Herman Fridman, Arnaud Méjean, Jean-Jacques Patard, Corinne Teghom, Reza Elaidi, Mathilde Sibony, Vincent Molinié, Nathalie Rioux-Leclercq, Nicolas Giraldo, Gabrielle Couchy, Virginie Verkarre, Alexandra Karadimou, Etienne Becht, Sylvie Job, Benoit Beuselinck
Supplemental Table 4-6. Table S4: Detail for each sample of the PBRM1 and VHL-mutation status. NA stands for Not Available. Table S5: For each data type, clinical, transcriptome, methylome or SNP array, sensitity and specificity of the two predictors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a692c2153cdf16e5909fb728ddb4c8
https://doi.org/10.1158/1078-0432.22459034
https://doi.org/10.1158/1078-0432.22459034
Autor:
Jessica Zucman-Rossi, Stéphane Oudard, Aurélien de Reyniès, Catherine Sautès-Fridman, Wolf Herman Fridman, Arnaud Méjean, Jean-Jacques Patard, Corinne Teghom, Reza Elaidi, Mathilde Sibony, Vincent Molinié, Nathalie Rioux-Leclercq, Nicolas Giraldo, Gabrielle Couchy, Virginie Verkarre, Alexandra Karadimou, Etienne Becht, Sylvie Job, Benoit Beuselinck
Supplemental Figure 7-10. Figure S7: Summary of the results obtained on the TCGA data; Figure S8: Survival analysis of the patients included in the TCGA according to our classification ccrcc 1 to 4; Figure S9: Illustration of the gradient assumption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26537c49a135b86602974887667f1990
https://doi.org/10.1158/1078-0432.22459040
https://doi.org/10.1158/1078-0432.22459040
Autor:
Didier Jean, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Jean-Claude Pairon, Fabien Petel, Sandrine Imbeaud, Pascal Andujar, Aurélie Cazes, Paul Hofman, Marie-Christine Copin, Françoise Galateau-Sallé, Nabila Elarouci, Ilir Hysi, Gabrielle Couchy, Annie Renier, Marie-Claude Jaurand, Aurélien de Reyniès
Purpose: Despite research efforts to develop more effective diagnostic and therapeutic approaches, malignant pleural mesothelioma (MPM) prognosis remains poor. The assessment of tumor response to therapy can be improved by a deeper phenotypical class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8d384bad683364139621ccb9d8a57c
https://doi.org/10.1158/1078-0432.c.6521894.v1
https://doi.org/10.1158/1078-0432.c.6521894.v1
Autor:
Didier Jean, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Jean-Claude Pairon, Fabien Petel, Sandrine Imbeaud, Pascal Andujar, Aurélie Cazes, Paul Hofman, Marie-Christine Copin, Françoise Galateau-Sallé, Nabila Elarouci, Ilir Hysi, Gabrielle Couchy, Annie Renier, Marie-Claude Jaurand, Aurélien de Reyniès
XLS file - 11306KB, Pathway analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c024ba7be0c0be4fcd0079cf9cf9897
https://doi.org/10.1158/1078-0432.22450274.v1
https://doi.org/10.1158/1078-0432.22450274.v1
Autor:
Didier Jean, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Jean-Claude Pairon, Fabien Petel, Sandrine Imbeaud, Pascal Andujar, Aurélie Cazes, Paul Hofman, Marie-Christine Copin, Françoise Galateau-Sallé, Nabila Elarouci, Ilir Hysi, Gabrielle Couchy, Annie Renier, Marie-Claude Jaurand, Aurélien de Reyniès
XLS file - 212KB, Sample annotations and gene expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d34597513fa41a29aa76b7f4251565
https://doi.org/10.1158/1078-0432.22450277.v1
https://doi.org/10.1158/1078-0432.22450277.v1