Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gabriella de Medeiros Abreu"'
Autor:
Ana Carolina Proença da Fonseca, Izadora Sthephanie da Silva Assis, Kaio Cezar Rodrigues Salum, Lohanna Palhinha, Gabriella de Medeiros Abreu, Verônica Marques Zembrzuski, Mario Campos Junior, José Firmino Nogueira-Neto, Amanda Cambraia, Mauro Lucio Ferreira Souza Junior, Clarissa Menezes Maya-Monteiro, Pedro Hernán Cabello, Patrícia Torres Bozza, João Regis Ivar Carneiro
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionObesity is a multifactorial disease associated with the development of many comorbidities. This disease is associated with several metabolic alterations; however, it has been shown that some individuals with obesity do not exhibit metabol
Externí odkaz:
https://doaj.org/article/ef0f3ba97c0946f49a666c8bbd0bfd90
Autor:
Gabriella de Medeiros Abreu, Roberta Magalhães Tarantino, Ana Carolina Proença da Fonseca, Juliana Rosa Ferreira de Oliveira Andrade, Ritiele Bastos de Souza, Camila de Almeida Pereira Dias Soares, Amanda Cambraia, Pedro Hernan Cabello, Melanie Rodacki, Lenita Zajdenverg, Verônica Marques Zembrzuski, Mário Campos Junior
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Monogenic forms of diabetes mellitus may affect a significant number of patients of this disease, and it is an important molecular cause to be investigated. However, studies of the genetic causes of monogenic diabetes, especially in populations with
Externí odkaz:
https://doaj.org/article/bc15666bdf6542a48d0adbf20b932cad
Autor:
Kaio Cezar Rodrigues Salum, Guilherme Orofino de Souza, Gabriella de Medeiros Abreu, Mário Campos Junior, Fabiana Barzotto Kohlrausch, João Regis Ivar Carneiro, José Firmino Nogueira Neto, Fernanda Cristina C. Mattos Magno, Eliane Lopes Rosado, Lohanna Palhinha, Clarissa Menezes Maya-Monteiro, Giselda Maria Kalil de Cabello, Pedro Hernán Cabello, Patrícia Torres Bozza, Verônica Marques Zembrzuski, Ana Carolina Proença da Fonseca
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
BackgroundThe melanocortinergic pathway orchestrates the energy homeostasis and impairments in this system often lead to an increase in body weight. Rare variants in the melanocortin 4 receptor (MC4R) gene resulting in partial or complete loss of fun
Externí odkaz:
https://doaj.org/article/2761b05651344a41966f54f212cb79cd
Autor:
Gabriella de Medeiros Abreu, Roberta Magalhães Tarantino, Pedro Hernan Cabello, Verônica Marques Zembrzuski, Ana Carolina Proença daFonseca, Melanie Rodacki, Lenita Zajdenverg, Mário Campos Junior
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 12, Pp n/a-n/a (2019)
Abstract Background MODY‐NEUROD1 is a rare form of monogenic diabetes caused by mutations in Neuronal differentiation 1 (NEUROD1). Until now, only a few cases of MODY‐NEUROD1 have been reported worldwide and the real contribution of mutations in
Externí odkaz:
https://doaj.org/article/cfee11bc33df43f691aaa8eec0732b4f
Autor:
Raisa da Silva Martins, Mario Campos Junior, Aline dosSantos Moreira, Verônica Marques Zembrzuski, Ana Carolina Proença daFonseca, Gabriella de Medeiros Abreu, Pedro Hernan Cabello, Giselda Maria Kalil deCabello
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 7, Pp n/a-n/a (2019)
Abstract Background Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). There are over 2000 different pathogenic and non‐pathogenic variants described in association with a broad clini
Externí odkaz:
https://doaj.org/article/fd5fc55e97ec4201a50be5c862f2c6c4
Autor:
Gabriella de Medeiros Abreu
Publikováno v:
Biblioteca Digital de Teses e Dissertações da UERJUniversidade do Estado do Rio de JaneiroUERJ.
Conselho Nacional de Desenvolvimento Científico e Tecnológico
A doença de Parkinson (DP) é a segunda doença neurodegenerativa mais frequente no mundo, afetando 1-2% da população acima de 65 anos, caracterizada clinicamente por tremor em r
A doença de Parkinson (DP) é a segunda doença neurodegenerativa mais frequente no mundo, afetando 1-2% da população acima de 65 anos, caracterizada clinicamente por tremor em r
Autor:
Roberta Magalhães Tarantino, Gabriella de Medeiros Abreu, Ana Carolina Proença de Fonseca, Rosane Kupfer, Maria de Fátima Carvalho Pereira, Mario Campos Júnior, Lenita Zajdenverg, Melanie Rodacki
Publikováno v:
Archives of Endocrinology and Metabolism
ABSTRACT Objective We aimed to identify the frequency of monogenic diabetes, which is poorly studied in multiethnic populations, due to GCK or HNF1A mutations in patients with suggestive clinical characteristics from the Brazilian population, as well
Externí odkaz:
https://doaj.org/article/82cfe7e7957049dd99b1ebcbb3c2fbeb
Autor:
Lenita Zajdenverg, Pedro Hernan Cabello, Ritiele Bastos de Souza, Roberta Magalhães Tarantino, Melanie Rodacki, Gabriella de Medeiros Abreu, Mario Campos Junior, Maria de Fátima Carvalho Pereira, Verônica Marques Zembrzuski, Ana Carolina Proença da Fonseca, Camila de Almeida Pereira Dias Soares
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 13:2623-2631
Purpose The aim of this study was to sequence the coding region of the PAX4 gene in a Brazilian cohort with clinical manifestations of monogenic diabetes. Patients and methods This study included 31 patients with autosomal dominant history of diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::526aa08a32536c74898588bf4a311b66
https://doi.org/10.2147/dmso.s256858
https://doi.org/10.2147/dmso.s256858
Autor:
Patrícia T. Bozza, José Firmino Nogueira Neto, Gabriella de Medeiros Abreu, Eliane Lopes Rosado, Mario Campos Junior, João Regis Ivar Carneiro, Pedro Hernan Cabello, Fernanda Cristina Carvalho Mattos Magno, Giselda M. K. Cabello, Verônica Marques Zembrzuski, Ana Carolina Proença da Fonseca
Publikováno v:
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity. 26:1399-1408
Monogenic forms of obesity are caused by single-gene variants which affect the energy homeostasis by increasing food intake and decreasing energy expenditure. Most of these variants result from disruption of the leptin–melanocortin signaling, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bab1e9d1e50e03a59710b189b114a2
https://doi.org/10.1007/s40519-020-00946-z
https://doi.org/10.1007/s40519-020-00946-z
Autor:
José Firmino Nogueira Neto, Gabriella de Medeiros Abreu, Pedro Hernan Cabello, João Regis Ivar Carneiro, Mario Campos Junior, Giselda M. K. Cabello, Verônica Marques Zembrzuski, Ana Carolina Proença da Fonseca
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12:667-684
Background: Obesity occurs due to the interaction between the genetic background and environmental factors, including an increased food intake and a sedentary lifestyle. Nowadays, it is clear that there is a specific circuit, called leptin-melanocort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7c31f17ed845b70f3fbd99d79b8828f
https://doi.org/10.2147/dmso.s199542
https://doi.org/10.2147/dmso.s199542