Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Gabriella Sekerková"'
Autor:
Gabriella Sekerková, Sumeyra Kilic, Yen-Hsin Cheng, Natalie Fredrick, Anne Osmani, Haram Kim, Puneet Opal, Marco Martina
Publikováno v:
Neurobiology of Disease, Vol 195, Iss , Pp 106492- (2024)
We performed a comprehensive study of the morphological, functional, and genetic features of moonwalker (MWK) mice, a mouse model of spinocerebellar ataxia caused by a gain of function of the TRPC3 channel. These mice show numerous behavioral symptom
Externí odkaz:
https://doaj.org/article/e3cfe5a94ab647d28f7573f7a49c8643
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1002032 (2011)
Hearing and vestibular function depend on mechanosensory staircase collections of hair cell stereocilia, which are produced from microvillus-like precursors as their parallel actin bundle scaffolds increase in diameter and elongate or shorten. Hair c
Externí odkaz:
https://doaj.org/article/50ff00f1315042dd8ca20126ab1613a9
Publikováno v:
Cell Rep
Breathing is coupled to metabolism. Leptin, a peptide mainly secreted in proportion to adipose tissue mass, increases energy expenditure with a parallel increase in breathing. We demonstrate that optogenetic activation of LepRb neurons in the nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc4094b1ba4f1eb917f864fa4f1a2ad
https://doi.org/10.1016/j.celrep.2020.108358
https://doi.org/10.1016/j.celrep.2020.108358
Autor:
Kathleen J. Millen, Christian Hansel, Gabriella Sekerková, Evelyn K. Shih, Enrico Mugnaini, Victor V. Chizhikov, Gen Ohtsuki, Kimberly A. Aldinger
Publikováno v:
The Cerebellum. 14:292-307
This study represents the first detailed analysis of the spontaneous neurological mouse mutant, tippy, uncovering its unique cerebellar phenotype. Homozygous tippy mutant mice are small, ataxic, and die around weaning. Although the cerebellum shows g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc9e5a01208a2799103bca6b1d574d4
https://doi.org/10.1007/s12311-014-0640-x
https://doi.org/10.1007/s12311-014-0640-x
Autor:
Macdonell J. Stanford, P. Hande Özdinler, Mukesh Gautam, Megan C. Schultz, Christine J. DiDonato, Gregory A. Cox, Daniel B. Heller, Jodi L. Klessner, Charles J. Heckman, Marin Manuel, Javier H. Jara, Barış Genç, Gabriella Sekerková
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Wiley, 2016, 3 (5), pp.331-345. ⟨10.1002/ACN3.298⟩
Annals of Clinical and Translational Neurology, Wiley, 2016, 3 (5), pp.331-345. ⟨10.1002/ACN3.298⟩
Objective The aim of this study was to investigate the role of ubiquitin C-terminal hydrolase-L1 (UCHL1) for motor neuron circuitry and especially in spinal motor neuron (SMN) health, function, and connectivity. Methods Since mutations in UCHL1 gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ccd5277a38937a3b5f002532a9f348
https://hal.archives-ouvertes.fr/hal-02415079
https://hal.archives-ouvertes.fr/hal-02415079
Autor:
Marco Martina, Gabriella Sekerková
Publikováno v:
Essentials of Cerebellum and Cerebellar Disorders ISBN: 9783319245492
Essentials of Cerebellum and Cerebellar Disorders ISBN: 9783031150692
Essentials of Cerebellum and Cerebellar Disorders ISBN: 9783031150692
The unipolar brush cells (UBCs) are excitatory interneurons in the granule cell layer of the cerebellar cortex. They amplify extra-cerebellar inputs from vestibular origin as well as other inputs whose origin is the focus of ongoing research. The UBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee5931a391bd48cf2ee6d5c24bbddd6
https://doi.org/10.1007/978-3-319-24551-5_26
https://doi.org/10.1007/978-3-319-24551-5_26
Publikováno v:
The Cerebellum. 11:1012-1025
Unipolar brush cells (UBCs) are excitatory cerebellar granular layer interneurons whose brush-like dendrites receive one-to-one mossy fiber inputs. Subclasses of UBCs differ primarily by expressing metabotropic glutamate receptor (mGluR) 1α or calre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e99175e5ede1d9381e2bab1896fd89d
https://doi.org/10.1007/s12311-012-0380-8
https://doi.org/10.1007/s12311-012-0380-8
Publikováno v:
Brain Research Reviews. 66:220-245
Unipolar brush cells (UBC) are small, glutamatergic neurons residing in the granular layer of the cerebellar cortex and the granule cell domain of the cochlear nuclear complex. Recent studies indicate that this neuronal class consists of three or mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8dcaf07aa7c7888240faf145ad1765
https://doi.org/10.1016/j.brainresrev.2010.10.001
https://doi.org/10.1016/j.brainresrev.2010.10.001
Publikováno v:
The Journal of Comparative Neurology. 509:661-676
The espins are Ca(2+)-resistant actin-bundling proteins that are enriched in hair cell stereocilia and sensory cell microvilli. Here, we report a novel localization of espins to a large proportion of rat type I spiral ganglion neurons (SGNs) and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98ad392fa1705fc9e675ab0e0a13afb
https://doi.org/10.1002/cne.21755
https://doi.org/10.1002/cne.21755
Autor:
Osamu Kakinohana, Seiya Nakamura, Kiyohiko Kinjo, Zoltán Tomori, Tatsuya Fuchigami, Neil Kurtz, Tony L. Yaksh, Michael P. Hefferan, Martin Marsala, Karolina Kucharova, Gabriella Sekerková
Publikováno v:
The Journal of Neuroscience. 27:11179-11191
Using a rat model of ischemic paraplegia, we examined the expression of spinal AMPA receptors and their role in mediating spasticity and rigidity. Spinal ischemia was induced by transient occlusion of the descending aorta combined with systemic hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409279404a439236ff5a1f104861b657
https://doi.org/10.1523/jneurosci.0989-07.2007
https://doi.org/10.1523/jneurosci.0989-07.2007