Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Gabriella Lupo"'
Autor:
Aleksandra Agafonova, Alessia Cosentino, Ivana Roberta Romano, Giovanni Giurdanella, Floriana D’Angeli, Rosario Giuffrida, Debora Lo Furno, Carmelina Daniela Anfuso, Giuliana Mannino, Gabriella Lupo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1774 (2024)
The blood–retinal barrier (BRB) is strongly compromised in diabetic retinopathy (DR) due to the detachment of pericytes (PCs) from retinal microvessels, resulting in increased permeability and impairment of the BRB. Western blots, immunofluorescenc
Externí odkaz:
https://doaj.org/article/ea89af614c264a8389c6297de4e0475d
Autor:
Naomi Osakabe, Sergio Modafferi, Maria Laura Ontario, Francesco Rampulla, Vincenzo Zimbone, Maria Rita Migliore, Tilman Fritsch, Ali S. Abdelhameed, Luigi Maiolino, Gabriella Lupo, Carmelina Daniela Anfuso, Elisabetta Genovese, Daniele Monzani, Uwe Wenzel, Edward J. Calabrese, R. Martin Vabulas, Vittorio Calabrese
Publikováno v:
Medicina, Vol 59, Iss 11, p 2045 (2023)
There is substantial experimental and clinical interest in providing effective ways to both prevent and slow the onset of hearing loss. Auditory hair cells, which occur along the basilar membrane of the cochlea, often lose functionality due to age-re
Externí odkaz:
https://doaj.org/article/5fa2a97c277b4196b482acec48382e8b
Autor:
Francesca Lazzara, Anna Maria Longo, Giovanni Giurdanella, Gabriella Lupo, Chiara Bianca Maria Platania, Settimio Rossi, Filippo Drago, Carmelina Daniela Anfuso, Claudio Bucolo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The impairment of the blood retinal barrier (BRB) represents one of the main features of diabetic retinopathy, a secondary microvascular complication of diabetes. Hyperglycemia is a triggering factor of vascular cells damage in diabetic retinopathy.
Externí odkaz:
https://doaj.org/article/1f7a2b9e4d354d2fadf8709d1e1f2a84
Autor:
Gabriella Lupo, Aleksandra Agafonova, Alessia Cosentino, Giovanni Giurdanella, Giuliana Mannino, Debora Lo Furno, Ivana Roberta Romano, Rosario Giuffrida, Floriana D’Angeli, Carmelina Daniela Anfuso
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 913 (2023)
Diabetic retinopathy (DR) is characterized by morphologic and metabolic alterations in endothelial cells (ECs) and pericytes (PCs) of the blood–retinal barrier (BRB). The loss of interendothelial junctions, increased vascular permeability, microane
Externí odkaz:
https://doaj.org/article/bae509e528da4295b2329016713d7a1b
Autor:
Carmelina Daniela Anfuso, Alessia Cosentino, Aleksandra Agafonova, Agata Zappalà, Giovanni Giurdanella, Angela Trovato Salinaro, Vittorio Calabrese, Gabriella Lupo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15790 (2022)
The stria vascularis (SV) contributes to cochlear homeostasis and consists of three layers, one of which contains the blood-labyrinthic barrier (BLB), with a large number of bovine cochlear pericytes (BCPs). Cisplatin is a chemotherapeutic drug that
Externí odkaz:
https://doaj.org/article/7221ae61836b4187a98799a2ef57cfa9
Autor:
Carmelina Daniela Anfuso, Giovanni Giurdanella, Anna Longo, Alessia Cosentino, Aleksandra Agafonova, Dario Rusciano, Gabriella Lupo
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 11, p 308 (2022)
Background: Reactive oxygen species (ROS) accumulation plays a pivotal role in the onset of cell damage induced by hyperglycemia and represents one of the major factors in the pathogenesis of diabetic retinopathy. In this study, we tested the antioxi
Externí odkaz:
https://doaj.org/article/2f006deadc934260aa39f07b26fbcea7
Autor:
Martina Cristaldi, Carmelina Daniela Anfuso, Giorgia Spampinato, Dario Rusciano, Gabriella Lupo
Publikováno v:
Applied Sciences, Vol 12, Iss 3, p 1268 (2022)
The aim of this study was to compare in vitro the protective and antioxidant properties of lutein and astaxanthin on human primary corneal epithelial cells (HCE-F). To this purpose, HCE-F cells were irradiated with a blue-violet light lamp (415–420
Externí odkaz:
https://doaj.org/article/1796e933a2a443c783fe1c520e5f14ba
Autor:
Giovanni Giurdanella, Anna Longo, Alfio Distefano, Melania Olivieri, Martina Cristaldi, Alessia Cosentino, Aleksandra Agafonova, Nunzia Caporarello, Gabriella Lupo, Carmelina Daniela Anfuso
Publikováno v:
Cells, Vol 11, Iss 1, p 51 (2021)
Hyperglycemia-induced impairment of the blood-retinal barrier represents the main pathological event in diabetic retinopathy that is elicited by a reduced cellular response to an accumulation of reactive oxygen species (ROS) and increased inflammatio
Externí odkaz:
https://doaj.org/article/fed1a1f398f7416f86591a30d59efb83
Autor:
Patrizia Di Pietro, Nunzia Caporarello, Carmelina D. Anfuso, Gabriella Lupo, Antonio Magrì, Diego La Mendola, Cristina Satriano
Publikováno v:
ACS Omega, Vol 2, Iss 8, Pp 4071-4079 (2017)
Externí odkaz:
https://doaj.org/article/063836f7d90b4195a54d82a6f82740d0
Autor:
Giovanni Giurdanella, Anna Longo, Loredana Salerno, Giuseppe Romeo, Sebastiano Intagliata, Gabriella Lupo, Alfio Distefano, Chiara Bianca Maria Platania, Claudio Bucolo, Giovanni Li Volti, Carmelina Daniela Anfuso, Valeria Pittalà
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 831 (2021)
Glucose induces corneal epithelial dysfunctions characterized by delayed wound repair. Nuclear erythroid 2-related factor 2 (Nrf2) mediates cell protection mechanisms even through the Heme oxygenase-1 (HO-1) up-regulation. Here, we synthesized new HO
Externí odkaz:
https://doaj.org/article/304c6803054d48d79144dbafd13fcaca