Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gabriella Di Luca"'
Publikováno v:
Helvetica Chimica Acta. 90:282-290
The regioselective total synthesis of the natural cerebroside (2R,15Z)-N-{(1S,2S,3R,4R,5Z)-1-[(β-D-glucopyranosyloxy)methyl]-2,3,4-trihydroxyheptadec-5-en-1-yl}-2-hydroxytetracos-15-enamide (2), originally isolated from Euphorbiaceae, is reported in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb0683bd06bd20209865ce10c48df2b
https://doi.org/10.1002/hlca.200790032
https://doi.org/10.1002/hlca.200790032
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(23)
A new and efficient method for the synthesis of PEG-6-mercaptopurine is described. The key feature of the proposed approach is the protection of the thiol group against metabolic inactivation. Preliminary in vivo and in vitro evaluations of the macro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15701cd9392a274cf908f7460df60e2e
https://pubmed.ncbi.nlm.nih.gov/17920267
https://pubmed.ncbi.nlm.nih.gov/17920267
Autor:
V. Maurich, Sara Drioli, Marina Zacchigna, Gian Maria Bonora, Francesca Cateni, Maurizio Ballico, Gabriella Di Luca
The successful conjugation of active theophylline molecules to two new multifunctional high-molecular weight poly(ethylene glycol) derivatives (MultiPEG) and their pharmacokinetic evaluations are reported. The drug loading was increased up to six tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16011912a1c044e36371b0e923e88e7a
http://hdl.handle.net/11368/1703085
http://hdl.handle.net/11368/1703085
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 23(4-5)
One of the most used and useful polymers, poly(ethylene glycol) (PEG) was used as a carrier for warfarin. The drug-polymer conjugate was freely water soluble at room temperature. The hydrolytic stability of the PEG-warfarin was investigated at physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a620ad513215a6696f05963add2303f1
https://pubmed.ncbi.nlm.nih.gov/15567291
https://pubmed.ncbi.nlm.nih.gov/15567291
Autor:
Lucia Lassiani, Antonio Varnavas, Marina Zacchigna, E. Boccù, Gabriella Di Luca, Anna Pitotti
Polyethylene glycols (PEGs) of various chain length were used to crosslink lysozyme onto an insoluble support such as oxirane. A very high degree of modification and no inactivation of lysozyme were obtained with PEG 20000, but enzymatic activity inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f0549023b30bd7ee7981f31a571d47
https://hdl.handle.net/11368/1703076
https://hdl.handle.net/11368/1703076