Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Gabriella Zupi"'
Autor:
Carlo Leonetti, Franco Zunino, Claudio Pisano, Gabriella Zupi, Giovanni Beretta, Eric Gilson, Malcolm F.G. Stevens, Marco Franceschin, Daniela Passeri, Augusto Orlandi, Carmen D'Angelo, Erica Salvati, Angela Rizzo, Manuela Porru, Annamaria Biroccio
Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7f047f016e298778b7e25575b1ac94
https://doi.org/10.1158/1078-0432.22442592.v1
https://doi.org/10.1158/1078-0432.22442592.v1
Autor:
Carlo Leonetti, Franco Zunino, Claudio Pisano, Gabriella Zupi, Giovanni Beretta, Eric Gilson, Malcolm F.G. Stevens, Marco Franceschin, Daniela Passeri, Augusto Orlandi, Carmen D'Angelo, Erica Salvati, Angela Rizzo, Manuela Porru, Annamaria Biroccio
Purpose: We previously reported that the G-quadruplex (G4) ligand RHPS4 potentiates the antitumor activity of camptothecins both in vitro and in tumor xenografts. The present study aims at investigating the mechanisms involved in this specific drug i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b30813e7f09b3f9e8aa8a552918a5d
https://doi.org/10.1158/1078-0432.c.6519282
https://doi.org/10.1158/1078-0432.c.6519282
Publikováno v:
Advances in Oncology ISBN: 9781315076409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8875efafcaa4c240455fce6a4b1c6508
https://doi.org/10.4324/9781315076409-8
https://doi.org/10.4324/9781315076409-8
Autor:
Ludovica Ciuffreda, Donatella Del Bufalo, Marianna Desideri, Cristina Di Sanza, Antonella Stoppacciaro, Maria Rosaria Ricciardi, Sabina Chiaretti, Simona Tavolaro, Barbara Benassi, Alfonso Bellacosa, Robin Foà, Agostino Tafuri, Francesco Cognetti, Andrea Anichini, Gabriella Zupi, Michele Milella
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 8, Pp 720-731 (2009)
The Raf/MEK/ERK pathway is an importantmediator of tumor cell proliferation and angiogenesis. Here, weinvestigated the growth-inhibitory and antiangiogenic properties of PD0325901, a novel MEK inhibitor, in human melanoma cells. PD0325901 effects wer
Externí odkaz:
https://doaj.org/article/038580e1415a4b73b5303a9bc6ede609
Autor:
Donatella Del Bufalo, Daniela Trisciuoglio, Marco Scarsella, Giulia D'Amati, Antonio Candiloro, Angela Iervolino, Carlo Leonetti, Gabriella Zupi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 5, Pp 513-522 (2004)
The aim of this study was to assess whether lonidamine (LND) interferes with some steps in angiogenesis progression. We report here, for the first time, that LND inhibited angiogenic-related endothelial cell functions in a dose-dependent manner (1-50
Externí odkaz:
https://doaj.org/article/fa8f9e2ff973440088bc46cd77bec953
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 3, Pp 195-206 (2004)
Here we investigate the mechanism(s) involved in the c-Myc-dependent drug response of melanoma cells. By using three M14-derived c-Myc low-expressing clones, we demonstrate that alkylating agents, cisplatin and melphalan, trigger apoptosis in the c-M
Externí odkaz:
https://doaj.org/article/d8676a4f609743dba66afd27cc7cd8ac
Autor:
Daniela Trisciuoglio, Chiara Gabellini, Marianna Desideri, Elio Ziparo, Gabriella Zupi, Donatella Del Bufalo
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11772 (2010)
BackgroundHypoxia-Inducible Factor 1 (HIF-1) is a transcription factor that is a critical mediator of the cellular response to hypoxia. Enhanced levels of HIF-1alpha, the oxygen-regulated subunit of HIF-1, is often associated with increased tumour an
Externí odkaz:
https://doaj.org/article/88d1f9e4a71241929c6265987760899e
Autor:
Fabio Ciccarone, Carmen D'Angelo, Anna Reale, Angela Catizone, Marta Chevanne, Angela Maria Rizzo, Tiziana Guastafierro, Michele Zampieri, Anna Biroccio, Gabriella Zupi, Paola Caiafa, Riccardo Caldini
Publikováno v:
Journal of Cellular Physiology. 222:401-410
The capability of PARP activity inhibitors to prevent DNA damage recovery suggested the use of these drugs as chemo- and radio-sensitisers for cancer therapy. Our research, carried out on cultured human M14 melanoma cells, was aimed to examine if PJ-
Autor:
Carmen D'Angelo, Eric Gilson, Gabriella Zupi, Angela Maria Rizzo, Annamaria Biroccio, Malcolm F. G. Stevens, Maurizio D'Incalci, Manuela Porru, Carlo Leonetti, Erica Salvati
Publikováno v:
Nucleic Acids Research
Functional telomeres are required to maintain the replicative ability of cancer cells and represent putative targets for G-quadruplex (G4) ligands. Here, we show that the pentacyclic acridinium salt RHPS4, one of the most effective and selective G4 l
Autor:
Laura Castellini, Gabriella Zupi, Daniela Trisciuoglio, Michael Kracht, Donatella Del Bufalo, Chiara Gabellini
Publikováno v:
Journal of Neurochemistry. 107:871-882
We recently reported that bcl-xL regulates interleukin 8 (CXCL8) protein expression and promoter activity in glioblastoma cells. In this paper we demonstrate that CXCL8 induction by bcl-xL is mediated through a nuclear factor-kappa B (NF-kB)-dependen