Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Gabriella, Pietra"'
Autor:
Claudia Cantoni, Michela Falco, Massimo Vitale, Gabriella Pietra, Enrico Munari, Daniela Pende, Maria Cristina Mingari, Simona Sivori, Lorenzo Moretta
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
The long story of NK cells started about 50 y ago with the first demonstration of a natural cytotoxic activity within an undefined subset of circulating leukocytes, has involved an ever-growing number of researchers, fascinated by the apparently easy
Externí odkaz:
https://doaj.org/article/bd0d6b7413d1468ca95bb84de00f4265
Autor:
Ombretta Garbarino, Giulia Elda Valenti, Lorenzo Monteleone, Gabriella Pietra, Maria Cristina Mingari, Andrea Benzi, Santina Bruzzone, Silvia Ravera, Riccardo Leardi, Emanuele Farinini, Stefania Vernazza, Melania Grottoli, Barbara Marengo, Cinzia Domenicotti
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundMalignant melanoma is the most lethal form of skin cancer which shows BRAF mutation in 50% of patients. In this context, the identification of BRAFV600E mutation led to the development of specific inhibitors like PLX4032. Nevertheless, alth
Externí odkaz:
https://doaj.org/article/b8c698a0f07f4ca591628ff66b119098
Autor:
Monica Parodi, Simonetta Astigiano, Paolo Carrega, Gabriella Pietra, Chiara Vitale, Laura Damele, Melania Grottoli, Maria de la Luz Guevara Lopez, Riccardo Ferracini, Giulia Bertolini, Ilaria Roato, Massimo Vitale, Paola Orecchia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Since the first studies, the mouse models have provided crucial support for the most important discoveries on NK cells, on their development, function, and circulation within normal and tumor tissues. Murine tumor models were initially set to study m
Externí odkaz:
https://doaj.org/article/0309575181784972bcbc9dc6dafb0a48
Autor:
Sabina Di Matteo, Enrico Munari, Piera Filomena Fiore, Silvia Santopolo, Camilla Sampaoli, Andrea Pelosi, Salem Chouaib, Nicola Tumino, Paola Vacca, Francesca Romana Mariotti, Stefan Ebert, Markus Machwirth, Dorothee Haas, Marco Pezzullo, Gabriella Pietra, Melania Grottoli, Stephanie Buart, Erwan Mortier, Enrico Maggi, Lorenzo Moretta, Ignazio Caruana, Bruno Azzarone
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMelanoma is a lethal skin cancer, and the risk of developing it is increased by exposure to ultraviolet (UV) radiation. The production of cytokines such as interleukin-15 (IL-15), induced by the exposure of skin cells to UV rays, could also
Externí odkaz:
https://doaj.org/article/019fa5592eae43aba1002be803c63084
Autor:
Anna Lisa Furfaro, Giulia Loi, Caterina Ivaldo, Mario Passalacqua, Gabriella Pietra, Giovanni Enrico Mann, Mariapaola Nitti
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1171 (2022)
Induction of heme oxygenase 1 (HO-1) favors immune-escape in BRAFV600 melanoma cells treated with Vemurafenib/PLX4032 under standard cell culture conditions. However, the oxygen tension under standard culture conditions (~18 kPa O2) is significantly
Externí odkaz:
https://doaj.org/article/1affae77ce5e44549d3f30919a187b1a
Autor:
Gabriella Pietra, Lorenzo Moretta, Nicola Tumino, Piera Filomena Fiore, Sabina Di Matteo, Francesca Romana Mariotti, Selene Ottonello, Simone Negrini, Barbara Bottazzi, Erwan Mortier, Bruno Azzarone
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Soluble interleukin (IL)-15 exists under two forms: as monomer (sIL-15) or as heterodimeric complex in association with sIL-15Rα (sIL-15/IL-15Rα). Both forms have been successfully tested in experimental tumor murine models and are currently underg
Externí odkaz:
https://doaj.org/article/801f8357ef2a451581b5b1020b7622d4
Autor:
Selene Ottonello, Carlo Genova, Irene Cossu, Vincenzo Fontana, Erika Rijavec, Giovanni Rossi, Federica Biello, Maria Giovanna Dal Bello, Marco Tagliamento, Angela Alama, Simona Coco, Simona Boccardo, Irene Vanni, Guido Ferlazzo, Lorenzo Moretta, Francesco Grossi, Maria Cristina Mingari, Paolo Carrega, Gabriella Pietra
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immune checkpoint blockade represents a major breakthrough in advanced non-small cell lung cancer (NSCLC) therapy. However, success is limited to a subset of patients and there is a critical need to identify robust biomarkers associated with clinical
Externí odkaz:
https://doaj.org/article/d2bc4156441047f087b7ab4cc39af254
Autor:
Paola Vacca, Gabriella Pietra, Nicola Tumino, Enrico Munari, Maria Cristina Mingari, Lorenzo Moretta
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
NK cells play an important role in the innate defenses against tumor growth and metastases. Human NK cell activation and function are regulated by an array of HLA class I-specific inhibitory receptors and activating receptors recognizing ligands expr
Externí odkaz:
https://doaj.org/article/c59929bb5dc94d338fc5ba318f43e3d7
Autor:
Daniela Pende, Michela Falco, Massimo Vitale, Claudia Cantoni, Chiara Vitale, Enrico Munari, Alice Bertaina, Francesca Moretta, Genny Del Zotto, Gabriella Pietra, Maria Cristina Mingari, Franco Locatelli, Lorenzo Moretta
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Natural killer (NK) cells contribute to the first line of defense against viruses and to the control of tumor growth and metastasis spread. The discovery of HLA class I specific inhibitory receptors, primarily of killer Ig-like receptors (KIRs), and
Externí odkaz:
https://doaj.org/article/0cfdf62edfb64d28ac62abd03e26e38e
Autor:
Massimo Vitale, Segundo González, Lorenzo Moretta, William Vermi, Maria Cristina Mingari, Marcella Marconi, Enrico Munari, Mattia Bugatti, Gabriella Pietra, Alejandro López-Soto, Mirna Balsamo, Enrique J. DeAndrés-Galiana, Andrea Petretto, Juan L. Fernández-Martínez, Chiara Lavarello, Claudia Cantoni, Monica Parodi, Leticía Huergo-Zapico
Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05ef9fd2740b02693a5ffab5ab91db6
https://doi.org/10.1158/0008-5472.22417152.v1
https://doi.org/10.1158/0008-5472.22417152.v1
