Výsledky vyhledávání - "Gabriele Wexel"

Does cefuroxime alter fracture healingin vivo? A micro-computertomographic, biomechanical, and histomorphometric evaluation using a rat fracture model

Autor: Oliver Bissinger, Klaus-Dietrich Wolff, Alexander Hapfelmeier, Peter Michael Prodinger, Kilian Kreutzer, Stephan Vogt, Gabriele Wexel, Thomas Tischer, Christoph Pautke

Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 105:2282-2291

Cefuroxime is widely used for antibiotic prophylaxis in orthopedic surgery. However, a recent study indicated a dose-dependent reduction in osteoblast function in vitro. Nevertheless, cell culture might not sufficiently imitate the complex process of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9783e089e3b205f76fa97a182e6c4a3f
https://doi.org/10.1002/jbm.b.33759

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Chondrocyte Culture Parameters for Matrix-Assisted Autologous Chondrocyte Implantation Affect Catabolism and Inflammation in a Rabbit Model

Autor: Markus T. Berninger, Martin Sauerschnig, Elizabeth R. Balmayor, Gian M. Salzmann, Valerie Wienerroither, Gabriele Wexel, Philip B. Schöttle, Martin Schönfelder, Theresa Kaltenhauser, Michael Plecko, Andreas B. Imhoff

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 7
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1545 (2019)

Cartilage defects represent an increasing pathology among active individuals that affects the ability to contribute to sports and daily life. Cell therapy, such as autologous chondrocyte implantation (ACI), is a widespread option to treat larger cart

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423432c67a9ca7e5d01334215e75a61f
https://doi.org/10.3390/ijms20071545

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Bisphosphonate related osteonecrosis of the jaw: A minipig large animal model

Autor: Daniela Münzel, Martina Knödler, Kilian Kreutzer, Sven Otto, Stephen R. Stürzenbaum, Jochen Weitz, Christoph Pautke, Gabriele Wexel, Alexander Hapfelmeier, Thomas Tischer

Publikováno v: Bone. 51:592-599

Bisphosphonate related osteonecrosis of the jaw (BRONJ) is rare but potentially severe, and the etiopathology and risk factors are poorly defined. To date, it has not been possible to induce BRONJ in a large animal model, a shortfall this study aims

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0610ca01397e53d449ba3c4e7cdb5d8d
https://doi.org/10.1016/j.bone.2012.04.020

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Platelet concentrate vs. saline in a rat patellar tendon healing model

Autor: Rainer Burgkart, Andreas B. Imhoff, Jeffrey T. Spang, Gian M. Salzmann, Tobias Winkler, Thomas Tischer, Gabriele Wexel

Publikováno v: Knee Surgery, Sports Traumatology, Arthroscopy. 19:495-502

To evaluate single centrifuge platelet concentrate as additive for improved tendon healing. Platelet-rich plasma has been reported to improve tendon healing. Single centrifuge platelet concentration may increase platelet concentration enough to posit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f695a407c2ca47e7ba5713c0ac020984
https://doi.org/10.1007/s00167-010-1291-1

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Characterization of eight different tetracyclines: advances in fluorescence bone labeling

Autor: Kilian Kreutzer, Stephan Vogt, Gabriele Wexel, Christoph Pautke, Horst Zitzelsberger, Andreas B. Imhoff, Cornelia Haczek, Andreas Kolk, Stefan Milz, Thomas Tischer

Publikováno v: Journal of Anatomy. 217:76-82

Polychrome sequential labeling with fluorochromes is a standard technique for the investigation of bone formation and regeneration processes in vivo. However, for human application, only tetracycline and its derivates are approved as fluorochromes. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e4fd67974a9454b30c358eebbd37bd1
https://doi.org/10.1111/j.1469-7580.2010.01237.x

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OCT-assisted control of catheter positioning in the urethra of the rabbit – A feasibility study

Autor: Walter Assmann, Michaela Püls, Kathrin Weick, Gabriele Wexel, P. Weidlich, Markus Bader, Ronald Sroka

Publikováno v: Medical Laser Application. 24:175-181

Background A fundamental precondition of local radiotherapy by means of 32 P-loaded urethral catheters is a precise position with respect to the target tissue. This feasibility study investigates optical coherence tomography (OCT)-assisted examinatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b2d7ddef8d771a887c6af16154823d5
https://doi.org/10.1016/j.mla.2009.03.002

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A Fibrin Glue Composition as Carrier for Nucleic Acid Vectors

Autor: Peter Ueblacker, Ulrike Schillinger, J. Aigner, Axel Stemberger, Jonas Wilisch, Martin Kullmer, Stephan Vogt, Michael Gerg, Christian Hacker, Gabriele Wexel, Christian Koch, Christian Plank, Axel Walch, Daniel Hensler, Thomas Tischer

Publikováno v: Pharmaceutical Research. 25:2946-2962

Gene delivery from biomaterials has become an important tool in tissue engineering. The purpose of this study was to generate a gene vector-doted fibrin glue as a versatile injectable implant to be used in gene therapy supported tissue regeneration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9c7b3e3ec430c2461302445cb745d4
https://doi.org/10.1007/s11095-008-9719-8

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Efficient and stable gene transfer of growth factors into chondrogenic cells and primary articular chondrocytes using a VSV.G pseudotyped retroviral vector

Autor: Achim Krüger, Martina Anton, Gabriele Wexel, Peter Ueblacker, Christopher Geis, Stephan Vogt, Bernd Gansbacher, Andreas B. Imhoff, Bettina Wagner, Christian Plank, Vladimir Martinek, Thomas Tischer

Publikováno v: Biomaterials. 29:1242-1249

Since efficient transfer of foreign genes into primary articular chondrocytes (CC) is difficult, a VSV.G pseudotyped retroviral vector (Bullet) was developed for marker and growth factor gene transfer. Transduction efficiency was analysed by FACS. BM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bc058865db5c43a966b02efc3a43ba
https://doi.org/10.1016/j.biomaterials.2007.11.013

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Polychrome labeling of bone with seven different fluorochromes: Enhancing fluorochrome discrimination by spectral image analysis

Autor: Herbert Deppe, Andreas Kolk, Stephan Vogt, Gabriele Wexel, Matthias Schieker, Stefan Milz, Thomas Tischer, Christoph Pautke

Publikováno v: Bone. 37:441-445

Bone formation and remodeling in vivo can be assessed by polychrome labeling using calcium-binding fluorescent dyes. The number of fluorochromes, however, limits this technique due to the fact that with increasing number, fluorescent spectra inevitab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d051ac44cdbd23bdb150a02769a354
https://doi.org/10.1016/j.bone.2005.05.008

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Stem cells and basic fibroblast growth factor failed to improve tendon healing: an in vivo study using lentiviral gene transfer in a rat model

Autor: Florian B. Imhoff, L Lenz, A. Wolf, D. Hirsch, Thomas Tischer, Stefan Milz, Andreas B. Imhoff, Ulrich Stöckle, Martina Anton, Gabriele Wexel, Stefan Buchmann, T M Kraus, Stephan Vogt

Publikováno v: The Journal of bone and joint surgery. American volume. 96(9)

Background The aim of this controlled study was to investigate the influence of mesenchymal stem cells (MSCs) and lentiviral (LV) expression of basic fibroblast growth factor (bFGF) on tendon remodeling in an in vivo rat model of an Achilles tendon d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441695d98eea6786cbd45976ac85cc7d
https://pubmed.ncbi.nlm.nih.gov/24806013

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