Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gabriele Weitnauer"'
Publikováno v:
Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications, Second Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::707b2cbca84eb95af8715a2aa7bb1a3a
https://doi.org/10.1002/9783527632909.ch2
https://doi.org/10.1002/9783527632909.ch2
Autor:
Andreas Bechthold, Irina Treede, Lene Jakobsen, Birte Vester, Finn Kirpekar, Stephen Douthwaite, Gabriele Weitnauer
Publikováno v:
Molecular Microbiology. 49:309-318
Avilamycin is an orthosomycin antibiotic that has shown considerable potential for clinical use, although it is presently used as a growth promoter in animal feed. Avilamycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a52608edc3556ec7484b7f4631f79e5
https://doi.org/10.1046/j.1365-2958.2003.03558.x
https://doi.org/10.1046/j.1365-2958.2003.03558.x
Autor:
Laurenz Kellenberger, Andreas Bechthold, Gabriele Weitnauer, Peter F. Leadlay, Sabine Gaisser
Publikováno v:
Microbiology. 148:373-379
Streptomyces viridochromogenes Tu57 is the principal producer of avilamycin A. aviG1, a putative methyltransferase gene, was detected in the avilamycin biosynthetic gene cluster. To determine the function of aviG1, a targeted gene inactivation experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc27310a0e78672f67d21086771da361
https://doi.org/10.1099/00221287-148-2-373
https://doi.org/10.1099/00221287-148-2-373
Autor:
Sibylle Gaisser, Andreas Bechthold, Carmen Méndez, Axel Trefzer, Lucy Westrich, José A. Salas, Gabriele Weitnauer, Luis M. Quirós, Sigrid Stockert
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:690-695
Three different resistance factors from the avilamycin biosynthetic gene cluster of Streptomyces viridochromogenes Tü57, which confer avilamycin resistance when expressed in Streptomyces lividans TK66, were isolated. Analysis of the deduced amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5243ee64d10c8375d412e1ff5144ce42
https://doi.org/10.1128/aac.45.3.690-695.2001
https://doi.org/10.1128/aac.45.3.690-695.2001
Autor:
Daniel W. Bearden, Ulrike Weissbach, Lucia Westrich, Jürgen Rohr, Andreas Bechthold,‡ and, Gabriele Weitnauer, Carsten Oelkers, Bettina Faust, Eva Künzel
Publikováno v:
Journal of the American Chemical Society. 121:11058-11062
A targeted search for glycosyltransferase (GT) encoding genes in the gene cluster of the urdamycin A producer Streptomyces fradiae Tu2717 resulted in the discovery of urdGT2, a GT encoding gene located approximately 7 kb downstream of the minimal pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d46d52e869090cc66b0403005c89423
https://doi.org/10.1021/ja9915347
https://doi.org/10.1021/ja9915347
Autor:
Björn Heitmann, Andreas Bechthold, Gabriele Weitnauer, Gerd Hauser, Anke Frerich, Clemens Dürr, Steffen J. Glaser, Raija Boll, Carsten Hofmann
Publikováno v:
Chemistrybiology. 12(10)
SummaryThe oligosaccharide antibiotic avilamycin A is composed of a polyketide-derived dichloroisoeverninic acid moiety attached to a heptasaccharide chain consisting of six hexoses and one unusual pentose moiety. We describe the generation of mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32c6eca8cd7ccff7631cac24038a472
https://pubmed.ncbi.nlm.nih.gov/16242656
https://pubmed.ncbi.nlm.nih.gov/16242656
Autor:
Andreas Bechthold, Irina Treede, Steffen J. Glaser, Carsten Hofmann, Maraike Schmidt, Agnes Mühlenweg, Gerd Hauser, Gabriele Weitnauer
Publikováno v:
Applied and environmental microbiology. 71(1)
Eurekanate belongs to the important class of branched-chain carbohydrates present in a wide variety of natural sources. It is a component of avilamycin A, a potent inhibitor of bacterial protein synthesis targeting the 50S ribosomal subunit. The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9aeabf572b5163549ae497894877867
https://pubmed.ncbi.nlm.nih.gov/15640214
https://pubmed.ncbi.nlm.nih.gov/15640214
Autor:
Irina, Treede, Lene, Jakobsen, Finn, Kirpekar, Birte, Vester, Gabriele, Weitnauer, Andreas, Bechthold, Stephen, Douthwaite
Publikováno v:
Molecular microbiology. 49(2)
Avilamycin is an orthosomycin antibiotic that has shown considerable potential for clinical use, although it is presently used as a growth promoter in animal feed. Avilamycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b78ad4c76582e6dbddcfd8ac3c304ddc
https://pubmed.ncbi.nlm.nih.gov/12828631
https://pubmed.ncbi.nlm.nih.gov/12828631
Publikováno v:
Current pharmaceutical biotechnology. 1(4)
Actinomycetes are gram-positive bacteria and commercially important microorganisms. They are producers of approximately two thirds of all bioactive compounds known and they produce a great variety of compounds which have clinical application on the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626766b07764c35d3df2021bfcfa4255
https://pubmed.ncbi.nlm.nih.gov/11467332
https://pubmed.ncbi.nlm.nih.gov/11467332
Autor:
Steffen J. Glaser, Ulrike Linder, Gerd Hauser, Carsten Hofmann, Klaus Pelz, Raija Boll, Andreas Bechthold, Gabriele Weitnauer
Publikováno v:
Chemistry & Biology. (10):1403-1411
The oligosaccharide antibiotics avilamycin A and C are produced by Streptomyces viridochromogenes Tü57. Both consist of a heptasaccharide chain, which is attached to a polyketide-derived dichloroisoeverninic acid moiety. They show excellent antibiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f21e0c40b8183e0841b0874c512f8b