Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Gabriele Todisco"'
Autor:
Jin Ye, Isabel A. Calvo, Itziar Cenzano, Amaia Vilas, Xabier Martinez-de-Morentin, Miren Lasaga, Diego Alignani, Bruno Paiva, Ana C. Viñado, Patxi San Martin-Uriz, Juan P. Romero, Delia Quilez Agreda, Marta Miñana Barrios, Ignacio Sancho-González, Gabriele Todisco, Luca Malcovati, Nuria Planell, Borja Saez, Jesper N. Tegner, Felipe Prosper, David Gomez-Cabrero
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104225- (2022)
Summary: Understanding the regulation of normal and malignant human hematopoiesis requires comprehensive cell atlas of the hematopoietic stem cell (HSC) regulatory microenvironment. Here, we develop a tailored bioinformatic pipeline to integrate publ
Externí odkaz:
https://doaj.org/article/ccde1bb022e24ec1a1f2e788e69807b2
Autor:
Lucia Masarova, Gabriele Todisco, Taghi Manshouri, Kate J. Newberry, Jorge E. Cortes, Hagop M. Kantarjian, Zeev Estrov, Srdan Verstovsek
Publikováno v:
Blood Advances, Vol 1, Iss 14, Pp 863-866 (2017)
Externí odkaz:
https://doaj.org/article/40f97f1374c040e98f22e72b21e61824
Autor:
Pedro L. Moura, Teresa Mortera-Blanco, Isabel J.F. Hofman, Gabriele Todisco, Warren W. Kretzschmar, Ann-Charlotte Björklund, Maria Creignou, Michael Hagemann-Jensen, Christoph Ziegenhain, David C. Granados, Indira Barbosa, Gunilla Walldin, Monika Jansson, Neil Ashley, Adam J. Mead, Vanessa Lundin, Marios Dimitriou, Tetsuichi Yoshizato, Petter S. Woll, Seishi Ogawa, Rickard Sandberg, Sten Eirik W. Jacobsen, Eva Hellström-Lindberg
Myelodysplastic syndromes with ring sideroblasts (MDS-RS) commonly originate from mutations in the splicing factorSF3B1(SF3B1mt).SF3B1mtcause RNA mis-splicing, mechanistically established as the major driver of RS development. However, little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fae7dc87665a7d64433d9df2ab65d3
https://doi.org/10.1101/2023.04.11.536355
https://doi.org/10.1101/2023.04.11.536355
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Supplementary Tables S1-S19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e51f56a5f32d341b5c2e51674ff765e
https://doi.org/10.1158/2643-3230.22543738
https://doi.org/10.1158/2643-3230.22543738
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Clonal hematopoiesis results from somatic mutations in cancer driver genes in hematopoietic stem cells. We sought to identify novel drivers of clonal expansion using an unbiased analysis of sequencing data from 84,683 persons and identified common mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55289da636eb1db4ca374a11330f8d09
https://doi.org/10.1158/2643-3230.c.6550390
https://doi.org/10.1158/2643-3230.c.6550390
Autor:
Maria Creignou, Elsa Bernard, Michael Crowther, Anna Tranberg, Elisabeth Ejerblad, Lars Nilsson, Hege Garelius, Petar Antunovic, Bengt Erik Holger Rasmussen, Fryderyk Lorenz, Gabriele Todisco, Gunilla Walldin, Teresa Mortera-Blanco, Monika Jansson, Magnus Tobiasson, Gustaf Edgren, Martin Jadersten, Elli Papaemmanuil, Eva Hellström-Lindberg
Publikováno v:
Blood. 140:6968-6970
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe606863b82f66cc77497c4120521d9f
https://doi.org/10.1182/blood-2022-155811
https://doi.org/10.1182/blood-2022-155811
Publikováno v:
Seminars in hematology. 59(3)
Large scale high-throughput DNA sequencing studies have identified clonal hematopoiesis (CH) as a clinical phenomenon characterized by a disproportionately large clonal population in the hematopoietic system with a shared mutational background. CH or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba414bd72c99a5b0e392b6751965427e
https://pubmed.ncbi.nlm.nih.gov/36115692
https://pubmed.ncbi.nlm.nih.gov/36115692
Autor:
Maciej Cieśla, Phuong Cao Thi Ngoc, Sowndarya Muthukumar, Gabriele Todisco, Magdalena Madej, Helena Fritz, Marios Dimitriou, Danny Incarnato, Eva Hellström-Lindberg, Cristian Bellodi
Publikováno v:
Molecular Cell, 83, 1165-1179. CELL PRESS
SF3B1 is the most mutated splicing factor (SF) in myelodysplastic syndromes (MDSs), which are clonal hematopoietic disorders with variable risk of leukemic transformation. Although tumorigenic SF3B1 mutations have been extensively characterized, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5403ae97d25682fee0cab59a56bd4b1
https://doi.org/10.1016/j.molcel.2023.02.024
https://doi.org/10.1016/j.molcel.2023.02.024
Autor:
Maria Creignou, Anna Gallì, Paola Guglielmelli, Mario Cazzola, Johanna Ungerstedt, Seishi Ogawa, Silvia Catricalà, Ettore Rizzo, Marios Dimitriou, Eva Hellström-Lindberg, Elisa Bono, Alessandro M. Vannucchi, Martina Sarchi, Elisa Rumi, Luca Malcovati, Vittorio Rosti, Yasuhito Nannya, Marco Roncador, Daniela Pietra, Chiara Elena, Elisabetta Molteni, Gabriele Todisco
Publikováno v:
Leukemia. 35:2371-2381
Somatic mutations in splicing factor genes frequently occur in myeloid neoplasms. While SF3B1 mutations are associated with myelodysplastic syndromes (MDS) with ring sideroblasts, SRSF2P95 mutations are found in different disease categories, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fcd9cf551b4f27c662eb2a7db01743e
https://doi.org/10.1038/s41375-020-01106-z
https://doi.org/10.1038/s41375-020-01106-z
Autor:
Martina Sarchi, Courtnee A Clough, Anna Gallì, Gabriele Todisco, J. Philip Creamer, Luca Malcovati, Sergei Doulatov
Publikováno v:
Blood. 140:211-212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51c01a790b22bb4383fefe47f67d00a8
https://doi.org/10.1182/blood-2022-164833
https://doi.org/10.1182/blood-2022-164833