Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Gabriele Schweikert"'
Autor:
Alex Hawkins-Hooker, Giovanni Visonà, Tanmayee Narendra, Mateo Rojas-Carulla, Bernhard Schölkopf, Gabriele Schweikert
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Epigenetic modifications are dynamic mechanisms involved in the regulation of gene expression. Unlike the DNA sequence, epigenetic patterns vary not only between individuals, but also between different cell types within an individual. Enviro
Externí odkaz:
https://doaj.org/article/8d8c4ed4fb5f4b7e99cc02481437355d
Autor:
Jacob Schreiber, Carles Boix, Jin wook Lee, Hongyang Li, Yuanfang Guan, Chun-Chieh Chang, Jen-Chien Chang, Alex Hawkins-Hooker, Bernhard Schölkopf, Gabriele Schweikert, Mateo Rojas Carulla, Arif Canakoglu, Francesco Guzzo, Luca Nanni, Marco Masseroli, Mark James Carman, Pietro Pinoli, Chenyang Hong, Kevin Y. Yip, Jeffrey P. Spence, Sanjit Singh Batra, Yun S. Song, Shaun Mahony, Zheng Zhang, Wuwei Tan, Yang Shen, Yuanfei Sun, Minyi Shi, Jessika Adrian, Richard Sandstrom, Nina Farrell, Jessica Halow, Kristen Lee, Lixia Jiang, Xinqiong Yang, Charles Epstein, J. Seth Strattan, Bradley Bernstein, Michael Snyder, Manolis Kellis, William Stafford, Anshul Kundaje, ENCODE Imputation Challenge Participants
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-22 (2023)
Abstract A promising alternative to comprehensively performing genomics experiments is to, instead, perform a subset of experiments and use computational methods to impute the remainder. However, identifying the best imputation methods and what measu
Externí odkaz:
https://doaj.org/article/af322f5b401248609628ec2ad86cadd9
Autor:
Velina S. Atanasova, Crhistian de Jesus Cardona, Václav Hejret, Andreas Tiefenbacher, Theresia Mair, Loan Tran, Janette Pfneissl, Kristina Draganić, Carina Binder, Julijan Kabiljo, Janik Clement, Katharina Woeran, Barbara Neudert, Sabrina Wohlhaupter, Astrid Haase, Sandra Domazet, Markus Hengstschläger, Markus Mitterhauser, Leonhard Müllauer, Boris Tichý, Michael Bergmann, Gabriele Schweikert, Markus Hartl, Helmut Dolznig, Gerda Egger
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1391-1419 (2023)
Background & Aims: Patient-derived organoid cancer models are generated from epithelial tumor cells and reflect tumor characteristics. However, they lack the complexity of the tumor microenvironment, which is a key driver of tumorigenesis and therapy
Externí odkaz:
https://doaj.org/article/4731d5078fae4db69082355f0d4fbdc9
Autor:
Seraina Blümli, Nicola Wiechens, Meng-Ying Wu, Vijender Singh, Marek Gierlinski, Gabriele Schweikert, Nick Gilbert, Catherine Naughton, Ramasubramanian Sundaramoorthy, Joby Varghese, Robert Gourlay, Renata Soares, David Clark, Tom Owen-Hughes
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109943- (2021)
Summary: The ARID1A subunit of SWI/SNF chromatin remodeling complexes is a potent tumor suppressor. Here, a degron is applied to detect rapid loss of chromatin accessibility at thousands of loci where ARID1A acts to generate accessible minidomains of
Externí odkaz:
https://doaj.org/article/04921146582c4b71a0ec2443dd1ee13e
Autor:
Dhaval Varshney, Olivia Lombardi, Gabriele Schweikert, Sianadh Dunn, Olga Suska, Victoria H. Cowling
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1530-1542 (2018)
Summary: mRNA cap addition occurs early during RNA Pol II-dependent transcription, facilitating pre-mRNA processing and translation. We report that the mammalian mRNA cap methyltransferase, RNMT-RAM, promotes RNA Pol II transcription independent of m
Externí odkaz:
https://doaj.org/article/73f6e7d714a24ffcbc0dae7def88aff4
Autor:
Rob van Nues, Gabriele Schweikert, Erica de Leau, Alina Selega, Andrew Langford, Ryan Franklin, Ira Iosub, Peter Wadsworth, Guido Sanguinetti, Sander Granneman
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Protein RNA interactions are dynamic and regulated in response to environmental changes. Here the authors describe ‘kinetic CRAC’, an approach that allows time resolved analyses of protein RNA interactions with minute time point resolution and ap
Externí odkaz:
https://doaj.org/article/4af8f874266d433eb3ee39b859f6ee20
Autor:
Sabine Lagger, John C Connelly, Gabriele Schweikert, Shaun Webb, Jim Selfridge, Bernard H Ramsahoye, Miao Yu, Chuan He, Guido Sanguinetti, Lawrence C Sowers, Malcolm D Walkinshaw, Adrian Bird
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006793 (2017)
Mutations in the gene encoding the methyl-CG binding protein MeCP2 cause several neurological disorders including Rett syndrome. The di-nucleotide methyl-CG (mCG) is the classical MeCP2 DNA recognition sequence, but additional methylated sequence tar
Externí odkaz:
https://doaj.org/article/1a9520b92d1044c68c65fae93e056e6c
Autor:
Akihiro Mori, Gabriele Schweikert
sEnhancers are genomic elements and contain all necessary cis-regulatory contexts. Such enhancers are convened to the appropriate promoter of target genes for gene regulations even though the enhancers and the promoters are apart a few mega-base pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf91948fc3ffdbea8a09353dbd859d84
https://doi.org/10.1101/2022.12.31.522397
https://doi.org/10.1101/2022.12.31.522397
Autor:
Luca Malinverno, Vesna Barros, Francesco Ghisoni, Giovanni Visonà, Roman Kern, Philip Nickel, Barbara Elvira Ventura, Ilija Šimić, Sarah Stryeck, Francesca Manni, Cesar Ferri, Claire Jean-Quartier, Laura Genga, Gabriele Schweikert, Mario Lovrić, Michal Rosen-Zvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8515724c1230eecdaf200d699680d672
https://doi.org/10.2139/ssrn.4335108
https://doi.org/10.2139/ssrn.4335108
Autor:
Velina S Atanasova, Crhistian de Jesus Cardona, Vaclav Hejret, Andreas Tiefenbacher, Loan Tran, Carina Binder, Theresia Mair, Julijan Kabiljo, Janik Clement, Katharina Woeran, Barbara Neudert, Markus Hengstschläger, Markus Mitterhauser, Leonhard Müllauer, Boris Tichy, Michael Bergmann, Gabriele Schweikert, Markus Hartl, Helmut Dolznig, Gerda Egger
Patient-derived organoid (PDO) cancer models are generated from epithelial tumor cells. Although they reflect the molecular tumor characteristics, they lack the complexity of the tumor microenvironment, which is a key driver of tumorigenesis and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7056150f57cf205623b4097a7bc3d202
https://doi.org/10.1101/2022.03.07.483214
https://doi.org/10.1101/2022.03.07.483214