Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Gabriele Schramm"'
Autor:
Verena von Bülow, Maryam Schneider, Dorothee Dreizler, Lena Russ, Anne Baier, Nicola Buss, Jakob Lichtenberger, Lukas Härle, Heike Müller, Annette Tschuschner, Gabriele Schramm, Jörn Pons-Kühnemann, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 107-117 (2024)
Background & Aims: Schistosomiasis is one of the most prominent parasite-induced infectious diseases, affecting more than 250 million people. Schistosoma mansoni causes metabolic exhaustion and a strong redox imbalance in the liver, causing parenchym
Externí odkaz:
https://doaj.org/article/03b592b3094a49659ed5de0bf1d43345
Autor:
Lena Russ, Verena von Bülow, Sarah Wrobel, Frederik Stettler, Gabriele Schramm, Franco H. Falcone, Christoph G. Grevelding, Martin Roderfeld, Elke Roeb
Publikováno v:
Cells, Vol 13, Iss 18, p 1579 (2024)
Schistosomiasis, a parasitic disease caused by Schistosoma spp., affects more than 250 million people worldwide. S. mansoni in particular affects the gastrointestinal tract and, through its eggs, induces a Th2 immune response leading to granuloma for
Externí odkaz:
https://doaj.org/article/d1c40398bf9f44c1a09e5e41c1422a8c
Autor:
Luís Almeida, Ruthger van Roey, Thiago Andrade Patente, Frank Otto, Tom Veldhuizen, Mohan Ghorasaini, Angela van Diepen, Gabriele Schramm, Jianyang Liu, Helena Idborg, Marina Korotkova, Per-Johan Jakobsson, Martin Giera, Cornelis Hendrik Hokke, Bart Everts
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The parasitic helminth Schistosoma mansoni is a potent inducer of type 2 immune responses by stimulating dendritic cells (DCs) to prime T helper 2 (Th2) responses. We previously found that S. mansoni soluble egg antigens (SEA) promote the synthesis o
Externí odkaz:
https://doaj.org/article/81da8022d2aa40008df4aeac71952bd4
Autor:
Verena von Bülow, Sarah Gindner, Anne Baier, Laura Hehr, Nicola Buss, Lena Russ, Sarah Wrobel, Victoria Wirth, Kuscha Tabatabai, Thomas Quack, Simone Haeberlein, Patrik Kadesch, Stefanie Gerbig, Katja R. Wiedemann, Bernhard Spengler, Annabel Mehl, Gertrud Morlock, Gabriele Schramm, Jörn Pons-Kühnemann, Franco H. Falcone, R. Alan Wilson, Katrin Bankov, Peter Wild, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Publikováno v:
JHEP Reports, Vol 5, Iss 2, Pp 100625- (2023)
Background & Aims: Schistosomiasis is a parasitic infection which affects more than 200 million people globally. Schistosome eggs, but not the adult worms, are mainly responsible for schistosomiasis-specific morbidity in the liver. It is unclear if S
Externí odkaz:
https://doaj.org/article/6e842731f44a4fffb93fb0d2ff32541f
Autor:
Jakob Weglage, Friederike Wolters, Laura Hehr, Jakob Lichtenberger, Celina Wulz, Felix Hempel, Anne Baier, Thomas Quack, Kernt Köhler, Thomas Longerich, Gabriele Schramm, Karuna Irungbam, Heike Mueller, Verena von Buelow, Annette Tschuschner, Margarete Odenthal, Uta Drebber, Maha El Arousy, Leandra N. Z. Ramalho, Katrin Bankov, Peter Wild, Jörn Pons-Kühnemann, Jonas Tschammer, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Schistosomiasis (bilharzia) is a neglected tropical disease caused by parasitic flatworms of the genus Schistosoma, with considerable morbidity in parts of the Middle East, South America, Southeast Asia, in sub-Saharan Africa, and particular
Externí odkaz:
https://doaj.org/article/4d888ac99c37449bb1555520699d6afe
Autor:
Lifang Wen, Xiaoru Dong, Qing Li, Gabriele Schramm, Bing Zhang, Detlef Zillikens, Ralf J. Ludwig, Frank Petersen, Xinhua Yu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disorder characterized and caused by autoantibodies against type VII collagen (COL7). Although it has been noticed that EBA in both patients and mice is associated with an increased sc
Externí odkaz:
https://doaj.org/article/4c9d1172ce1d41609f89ead4cd0b73e0
Autor:
Kevin K Takaki, Francisco J Roca, Gabriele Schramm, Ruud H P Wilbers, Wannaporn Ittiprasert, Paul J Brindley, Gabriel Rinaldi, Matthew Berriman, Lalita Ramakrishnan, Antonio J Pagán
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008814 (2021)
Infections by schistosomes result in granulomatous lesions around parasite eggs entrapped within the host tissues. The host and parasite determinants of the Schistosoma mansoni egg-induced granulomatous response are areas of active investigation. Som
Externí odkaz:
https://doaj.org/article/61da5d83500e4279a2033dc12ad60ad2
Autor:
Gabriele Schramm, Abdulhadi Suwandi, Alibek Galeev, Samriti Sharma, Janin Braun, Anne-Kathrin Claes, Peter Braubach, Guntram A. Grassl
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Countries with a high incidence of helminth infections are characterized by high morbidity and mortality to infections with intracellular pathogens such as Salmonella. Some patients with Salmonella-Schistosoma co-infections develop a so-called “chr
Externí odkaz:
https://doaj.org/article/6271062b085743fe944567e3655092c8
Autor:
Katrin Knuhr, Kristina Langhans, Sandra Nyenhuis, Kerstin Viertmann, Anna M. Overgaard Kildemoes, Michael J. Doenhoff, Helmut Haas, Gabriele Schramm
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Schistosomes control inflammation in their hosts via highly effective mechanisms such as induction of Tregs, Bregs, and alternatively activated macrophages (AAMs). Notably, IPSE/alpha-1, the major secretory product from Schistosoma mansoni eggs, trig
Externí odkaz:
https://doaj.org/article/16fa3a68191546838fd80e8058ca0b42
Autor:
Maria M M Kaisar, Manuel Ritter, Carlos Del Fresno, Hulda S Jónasdóttir, Alwin J van der Ham, Leonard R Pelgrom, Gabriele Schramm, Laura E Layland, David Sancho, Clarissa Prazeres da Costa, Martin Giera, Maria Yazdanbakhsh, Bart Everts
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e2005504 (2018)
The molecular mechanisms through which dendritic cells (DCs) prime T helper 2 (Th2) responses, including those elicited by parasitic helminths, remain incompletely understood. Here, we report that soluble egg antigen (SEA) from Schistosoma mansoni, w
Externí odkaz:
https://doaj.org/article/7a38510782a14c2186de5dcce6c3a2f5