Effects of Combined Endothelin and Angiotensin II Antagonism on Growth Factor-Induced Proliferation of Vascular Smooth Muscle Cells Isolated from Uremic Rats

Autor: Bernhard R. Brehm, Gabriele Sauter, Sabine C. Wolf, Teut Risler

Publikováno v: Renal Failure. 27:465-474

Background. The activation of both the renin–angiotensin–aldosterone and endothelin (ET) system in uremia contributes to the development of cardiovascular disease. The combination of ET receptor antagonists and inhibitors of the angiotensin-conve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0b45e675d6cf15f7dce939111bc8448
https://doi.org/10.1081/jdi-65421

A highly selective telomerase inhibitor limiting human cancer cell proliferation

Autor: Norbert Hauel, Ines Lauritsch, Bernd Guilliard, Andreas Schnapp, Iris Kauffmann, Joachim Lingner, Uwe M. Martens, Ulrike Hemmann, Christian Wenz, Barbara Enenkel, Claudia Niestroj, Wolfgang J. Rettig, Milena Pantic, Henning Priepke, Emanuelle Pascolo, Pilar Garin-Chesa, Norbert Kraut, Elfriede Müller, Gabriele Sauter, Klaus Damm, Christine Daiber

Publikováno v: The EMBO Journal. 20:6958-6968

Telomerase, the ribonucleoprotein enzyme maintaining the telomeres of eukaryotic chromosomes, is active in most human cancers and in germline cells but, with few exceptions, not in normal human somatic tissues. Telomere maintenance is essential to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0544b5564a1a136e85e2b69aac70c7a
https://doi.org/10.1093/emboj/20.24.6958

Anschriften der Herausgeber und Autoren

Autor: M. Dollinger, Jürgen Schölmerich, Martina Mayr, Alexander L. Gerbes, Alexandra Keinert, Markus Kuczyk, Gert Richardt, Jutta Keller, Bernhard J. Steinhoff, Karsten Müssig, Johannes Strunk, Oliver Gross, Marc-Sören Hochtritt, Stefan Gölder, Marius M. Höper, Tilman Sauerbruch, Sandra Waalkes, Matthias Eder, Jens Heinz Gerth, Gabriele Sauter, Michael Pfeifer, Gert Meyer, Ulrike Woenckhaus, Hans-Jürgen Welkoborsky, Stefan Zeuzem, Jürgen Pausch, Bernd Schönhofer, Wolff Schmiegel, Michael Trauner, Thomas Weiss, Friedrich von Weizsäcker, Hans-Dieter Allescher, Florian Obermeier, Markus Lerch, Robert Koch, Michael Nebel, Dominic Dellweg, Volker Groß, Andreas Schwartz, Brigitta Rumberger, Jost Niedermeyer, Robert Dinser, Bernd Salzberger, Roland Büttner, Mirja Hickstein, Martin Holtmann, Britta Siegmund, Peter Brunotte, Peter Wagener, Martin-Walter Welker, Anke Möller, Jürgen Tebbenjohanns, Reinhard Brunkhorst, Christian Teschendorf, Michael Pfreundschuh, Ralph Tölg, Klaus-Peter Czudaj, Viola Hach-Wunderle, Walter Reinisch, Beate Gleissner, Theodoros Thomas, Jürgen Wilke, Andreas Stallmach, Peter Fickert, Peter Layer, Gabriele Birkenfeld, Felix Flohr, Thomas Fühner, Uwe Wiegand, Cornelius Bollheimer, Frank Lammert, Dorothee Dorlars, Thomas R. W. Herrmann, Hans-Peter Lorenzen, Tobias Welte, Christoph Schrader, Peter Simon, Thomas Berger, Gunter Wolf, Ulf Müller-Ladner, Christoph Tillmanns, Christian Wrede, Gerhard A. Müller, Johannes Hensen, Reinhard Dengler, Herbert Bruckmayer, Andrea Titz, Wolf Harms, Susanne Petri, Julia Mayerle, Markus Gaubitz, Michael Hamm, Carsten Schmidt, Reiner Wiest, Urs Lichtenauer, Ulf Landmesser, Esther Endlicher, Herbert Tilg, Katharina Laubner, Peter Otto, Matthias Löhr, Helmut Messmann, Matthias Ebert, Silke Hörnschemeyer-Decker, Stefan Köppen, Karin Wollersen, Axel S. Merseburger, Erwin Stark, Sarah Kaufmann, Guntram Lock, Ingo H. Tarner, Stephanie Mayer, Baptist Gallwitz, Peter Staib, Peter Berlit, Ingvild Hansen, Thomas Glück, Oliver Kastrup, Michael Seidler, Dietrich D. Gulba, Jochen Seufert, Friedrich Schorr, Jürgen Weiß, Ahmed A. Khattab, Felix J. F. Herth, Marianne Haag-Weber, Klaus G. Parhofer, Christiane Girlich, Markus Fahlbusch, Phillipe Schafhausen, Manfred Kuhn, Mathias Pletz, Burkhard Wiechens, Ralph Naumann, Jens Panse, Felix Rockmann

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5e2051ffb10d4cc2045c8e0b6f6fc4b
https://doi.org/10.1016/b978-3-437-42501-1.50005-3

Influence of nebivolol and metoprolol on inflammatory mediators in human coronary endothelial or smooth muscle cells. Effects on neointima formation after balloon denudation in carotid arteries of rats treated with nebivolol

Autor: Gabriele Sauter, Volkhard A. J. Kempf, Maria Preyer, Sabine C. Wolf, Teut Risler, Tudor C. Poerner, Bernhard R. Brehm

Publikováno v: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 19(1-4)

Objective and Background: Inflammation plays a critical role in all stages of atherogenesis. Proliferating vascular smooth muscle cells (SMC) and endothelial cells (EC) enhancing the inflammatory response, both contribute to the progression of athero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b63550003d6a7d166a4b6d1a398d781
https://pubmed.ncbi.nlm.nih.gov/17310107

Endothelin-1 regulates protein kinase C isoforms differently in smooth muscle cells and in cardiomyocytes

Autor: Bernhard R. Brehm, Sabine C. Wolf, Teut Risler, Christian Brodbeck, Gabriele Sauter

Publikováno v: Journal of cardiovascular pharmacology. 44

Endothelin-1 (ET-1) is known to increase the mitotic response of different growth factors but also to different vasoactive hormones already at threshold concentrations. The aim of this study was to investigate the influence of chronic elevated ET-1 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e655c0828368aaa53c2f3fb487432919
https://pubmed.ncbi.nlm.nih.gov/15838306