Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Gabriele S Kaminski Schierle"'
Autor:
Raimund Jung, Marie C Lechler, Ana Fernandez-Villegas, Chyi Wei Chung, Harry C Jones, Yoon Hee Choi, Maximilian A Thompson, Christian Rödelsperger, Waltraud Röseler, Gabriele S Kaminski Schierle, Ralf J Sommer, Della C David
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002284 (2023)
During aging, proteostasis capacity declines and distinct proteins become unstable and can accumulate as protein aggregates inside and outside of cells. Both in disease and during aging, proteins selectively aggregate in certain tissues and not other
Externí odkaz:
https://doaj.org/article/6e413ad3f27943b5974f39bac00f3cda
Autor:
Chaolie Huang, Sara Wagner-Valladolid, Amberley D Stephens, Raimund Jung, Chetan Poudel, Tessa Sinnige, Marie C Lechler, Nicole Schlörit, Meng Lu, Romain F Laine, Claire H Michel, Michele Vendruscolo, Clemens F Kaminski, Gabriele S Kaminski Schierle, Della C David
Publikováno v:
eLife, Vol 8 (2019)
Reduced protein homeostasis leading to increased protein instability is a common molecular feature of aging, but it remains unclear whether this is a cause or consequence of the aging process. In neurodegenerative diseases and other amyloidoses, spec
Externí odkaz:
https://doaj.org/article/d304ea99735c4d8ea67842213713ac7f
Autor:
Bismoy Mazumder, Meng Lu, Hassan Rahmoune, Ana Fernandez-Villegas, Edward Ward, Min Wang, Jiaoyan Ren, Yi Yu, Ting Zhang, Ming Liang, Wenzhi Li, Nino F. Läubli, Clemens F. Kaminski, Gabriele S. Kaminski Schierle
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117466- (2024)
Our skin serves as the primary barrier against external environmental insults, the latter of which can cause oxidative stress within cells, while various bioactive peptides sourced from natural resources hold promise in protecting cells against such
Externí odkaz:
https://doaj.org/article/0ef683c9ab264ee5997bc76adef6166e
Autor:
Tim Davies, Noriyuki Kodera, Gabriele S Kaminski Schierle, Eric Rees, Miklos Erdelyi, Clemens F Kaminski, Toshio Ando, Masanori Mishima
Publikováno v:
PLoS Biology, Vol 13, Iss 4, p e1002121 (2015)
Centralspindlin, a constitutive 2:2 heterotetramer of MKLP1 (a kinesin-6) and the non-motor subunit CYK4, plays important roles in cytokinesis. It is crucial for the formation of central spindle microtubule bundle structure. Its accumulation at the c
Externí odkaz:
https://doaj.org/article/2a18183aca604b2cb4f192f662639bd1
Autor:
Zixuan Lu, Chiara Barberio, Ana Fernandez‐Villegas, Aimee Withers, Alexandra Wheeler, Konstantinos Kallitsis, Eleonora Martinelli, Achilleas Savva, Becky M. Hess, Anna‐Maria Pappa, Gabriele S. Kaminski Schierle, Róisín M. Owens
Publikováno v:
Advanced Science, Vol 11, Iss 27, Pp n/a-n/a (2024)
Abstract Drug studies targeting neuronal ion channels are crucial to understand neuronal function and develop therapies for neurological diseases. The traditional method to study neuronal ion‐channel activities heavily relies on the whole‐cell pa
Externí odkaz:
https://doaj.org/article/096d55a692a94d6ea7e3e0a09313df3a
Autor:
Minkoo Ahn, Erwin De Genst, Gabriele S Kaminski Schierle, Miklos Erdelyi, Clemens F Kaminski, Christopher M Dobson, Janet R Kumita
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50192 (2012)
Fibril formation by mutational variants of human lysozyme is associated with a fatal form of hereditary non-neuropathic systemic amyloidosis. Defining the mechanistic details of lysozyme aggregation is of crucial importance for understanding the orig
Externí odkaz:
https://doaj.org/article/af834fbbb2454b1291436923ef50ee50
Autor:
Uriel N. Morzan, Gonzalo Díaz Mirón, Luca Grisanti, Mariano C. González Lebrero, Gabriele S. Kaminski Schierle, Ali Hassanali
Publikováno v:
The Journal of Physical Chemistry B. 126:7203-7211
While in the vast majority of cases fluorescence in biological matter has been attributed to aromatic or conjugated groups, peptides associated with neurodegenerative diseases, such as Alzheimer's, Parkinson's, or Huntington's, have been recently sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e66a35bede76855e49b46530ea49a5
https://doi.org/10.1021/acs.jpcb.2c04280
https://doi.org/10.1021/acs.jpcb.2c04280
Autor:
Geyunjian H. Zhu, Mohammad Azharuddin, Bapan Pramanik, Karin Roberg, Sujoy Kumar Biswas, Padraig D’arcy, Meng Lu, Apanpreet Kaur, Alexander Chen, Ashis Kumar Dhara, Alexandru Chivu, Yunhui Zhuang, Andrew Baker, Xiewen Liu, David Fairen-Jimenez, Bismoy Mazumder, Rongjun Chen, Clemens F. Kaminski, Gabriele S. Kaminski Schierle, Jorma Hinkula, Nigel K. H. Slater, Hirak K. Patra
Despite the enormous advancements in nanomedicine research, a limited number of nanoformulations are available on the market, and few have been translated to clinics. An easily scalable, sustainable, and cost-effective manufacturing strategy and long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0f13696b9a6028dd685ee215dd2e30
http://hdl.handle.net/10044/1/103633
http://hdl.handle.net/10044/1/103633
Autor:
Meng Lu, Charles N. Christensen, Jana M. Weber, Tasuku Konno, Nino F. Läubli, Katharina M. Scherer, Edward Avezov, Pietro Lio, Alexei A. Lapkin, Gabriele S. Kaminski Schierle, Clemens F. Kaminski
The ability to quantify structural changes of the endoplasmic reticulum (ER) is crucial for understanding the structure and function of this organelle. However, the rapid movement and complex topology of ER networks make this challenging. Here, we co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574e05fd2863525c87278e73013f73e6
Autor:
Gonzalo Díaz Mirón, Jonathan A. Semelak, Luca Grisanti, Alex Rodriguez, Irene Conti, Martina Stella, Nicola Seriani, Nađa Došlić, Ivan Rivalta, Marco Garavelli, Dario A. Estrin, Gabriele S. Kaminski Schierle, Mariano C. González Lebrero, Ali Hassanali, Uriel N. Morzan
Challenging the basis of our chemical intuition, recent experimental evidence reveals the presence of a new type of intrinsic fluorescence in biomolecules that exists even in the absence of aromatic or electronically conjugated chemical compounds. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8076c21b3c77824874d116d6aa9d709
https://doi.org/10.26434/chemrxiv-2023-kdfc9
https://doi.org/10.26434/chemrxiv-2023-kdfc9