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Publikováno v:
Journal f�r Praktische Chemie/Chemiker-Zeitung. 336:233-236
The solid-phase synthesis of the dodecaribonucleotide ACCACUAAAGCG is described using the tert. butyloxycarbonyl (Boc) as 2′-OH-protecting group. The synthesis was carried out on a filter disc support Whatman 3 MM by the phosphotriester method. Und
Autor:
G. Losse, Gabriele Süptitz
Publikováno v:
Synthesis. 1990:1035-1036
A method for the introduction of the tert-butyloxycarbonyl-group (Boc) preferentially into the 2'-OH position of the ribonucleosides cytidine, uridine, adenosine and guanosine is described, resulting in derivatives especially applicable for ribonucle
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. :985-992
Whereas treatment of the ethyl 5-acetyl-2-amino-4-methyl-thiophene-3-carboxylate (1) with potassium hydroxide yields the 2-hydroxy-thiophene-3-carbonitrile4 its hydrazone2 is converted into the 1-amino-5-mercapto-2-pyridone derivative6. The transform