Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Gabriele Pfitzer"'
Autor:
Lubomir T. Lubomirov, Mechthild M. Schroeter, Veronika Hasse, Marina Frohn, Doris Metzler, Maria Bust, Galyna Pryymachuk, Jürgen Hescheler, Olaf Grisk, Joseph M. Chalovich, Neil R. Smyth, Gabriele Pfitzer, Symeon Papadopoulos
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Stretch-induced vascular tone is an important element of autoregulatory adaptation of cerebral vasculature to maintain cerebral flow constant despite changes in perfusion pressure. Little is known as to the regulation of tone in senescent basilar art
Externí odkaz:
https://doaj.org/article/19a2ea5031624db0a6613a250fb065b3
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Length-dependent activation of calcium-dependent myocardial force generation provides the basis for the Frank-Starling mechanism. To directly compare the effects of mutations associated with hypertrophic cardiomyopathy and dilated cardiomyopathy, the
Externí odkaz:
https://doaj.org/article/d8708fa5c20643a5a4ec1230b1c6bb17
Autor:
Diana Cimiotti, Setsuko Fujita-Becker, Desirée Möhner, Natalia Smolina, Heidi Budde, Aline Wies, Lisa Morgenstern, Alexandra Gudkova, Thomas Sejersen, Gunnar Sjöberg, Andreas Mügge, Marc M Nowaczyk, Peter Reusch, Gabriele Pfitzer, Robert Stehle, Rasmus R Schröder, Hans G Mannherz, Anna Kostareva, Kornelia Jaquet
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229227 (2020)
TNNI3 encoding cTnI, the inhibitory subunit of the troponin complex, is the main target for mutations leading to restrictive cardiomyopathy (RCM). Here we investigate two cTnI-R170G/W amino acid replacements, identified in infantile RCM patients, whi
Externí odkaz:
https://doaj.org/article/bb47d502141e46aba86a3a8e42223132
Autor:
Roua Hassoun, Heidi Budde, Hans Georg Mannherz, Mária Lódi, Setsuko Fujita-Becker, Kai Thorsten Laser, Anna Gärtner, Karin Klingel, Desirée Möhner, Robert Stehle, Innas Sultana, Thomas Schaaf, Mario Majchrzak, Verena Krause, Christian Herrmann, Marc M. Nowaczyk, Andreas Mügge, Gabriele Pfitzer, Rasmus R. Schröder, Nazha Hamdani, Hendrik Milting, Kornelia Jaquet, Diana Cimiotti
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9625 (2021)
Rare pediatric non-compaction and restrictive cardiomyopathy are usually associated with a rapid and severe disease progression. While the non-compaction phenotype is characterized by structural defects and is correlated with systolic dysfunction, th
Externí odkaz:
https://doaj.org/article/25849db75a5c4b46ae7f78d734102676
Autor:
Stefanie Diermeier, Julian Iberl, Kristina Vetter, Michael Haug, Charlotte Pollmann, Barbara Reischl, Andreas Buttgereit, Sebastian Schürmann, Marina Spörrer, Wolfgang H. Goldmann, Ben Fabry, Fatiha Elhamine, Robert Stehle, Gabriele Pfitzer, Lilli Winter, Christoph S. Clemen, Harald Herrmann, Rolf Schröder, Oliver Friedrich
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract In striated muscle, desmin intermediate filaments interlink the contractile myofibrillar apparatus with mitochondria, nuclei, and the sarcolemma. The desmin network’s pivotal role in myocytes is evident since mutations in the human desmin
Externí odkaz:
https://doaj.org/article/34b6157e38954bd2be2d2f1991aef0fe
Autor:
Dilyana Filipova, Margit Henry, Tamara Rotshteyn, Anna Brunn, Mariana Carstov, Martina Deckert, Jürgen Hescheler, Agapios Sachinidis, Gabriele Pfitzer, Symeon Papadopoulos
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194428 (2018)
In skeletal muscle the coordinated actions of two mechanically coupled Ca2+ channels-the 1,4-dihydropyridine receptor (Cav1.1) and the type 1 ryanodine receptor (RYR1)-underlie the molecular mechanism of rapid cytosolic [Ca2+] increase leading to con
Externí odkaz:
https://doaj.org/article/0922971a611a48d1ada767dae8f53458
Autor:
Fatiha Elhamine, Bogdan Iorga, Martina Krüger, Mona Hunger, Jan Eckhardt, Narayanswami Sreeram, Gerardus Bennink, Konrad Brockmeier, Gabriele Pfitzer, Robert Stehle
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 6 (2016)
BackgroundThe postnatal development of myofibrillar mechanics, a major determinant of heart function, is unknown in pediatric patients with tetralogy of Fallot and related structural heart defects. We therefore determined the mechanical properties of
Externí odkaz:
https://doaj.org/article/9dd632a9d454423ab6144c4928ffd78f
Autor:
Gabriele Pfitzer
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 475:557-559
Autor:
Lubomir T. Lubomirov, René Mantke, Thomas Enzmann, Doris Metzler, Tatiana Korotkova, Jürgen Hescheler, Gabriele Pfitzer, Olaf Grisk
Publikováno v:
Journal of Hypertension.
Autor:
Marco Herling, Stefan Barth, Gabriele Pfitzer, Michael Hallek, Mehmet Kemal Tur, Carmen Diana Herling, Petra Mayer, Stefan Zittrich, Elena Vasyutina, Giuliano Crispatzu, Gregor Lohmann, Nils Lilienthal
Table S1: Expression of DAPK1 (a) and surface CD22 (b) in various cell lines; Table S2: Characteristics of CLL patients from whom samples were analyzed including for DAPK1/2 expression and responses to DK1KD-SGIII;Figure S1: Analysis of DAPK expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c807a8909e83e1222a0f4b5ad8c8005
https://doi.org/10.1158/1535-7163.22508455.v1
https://doi.org/10.1158/1535-7163.22508455.v1