Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gabriele Mild"'
Autor:
Shivam Rai, Elodie Grockowiak, Nils Hansen, Damien Luque Paz, Cedric B. Stoll, Hui Hao-Shen, Gabriele Mild-Schneider, Stefan Dirnhofer, Christopher J. Farady, Simón Méndez-Ferrer, Radek C. Skoda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Inflammatory cytokines are elevated in patients with myeloproliferative neoplasms (MPN). Here the authors show that the JAK2-V617F mutation is associated with increased expression of IL-1 in MPN patients and that loss of IL-1β in JAK2-V617F mutant h
Externí odkaz:
https://doaj.org/article/9e49c6b3c0a84551bf6d7fb1d605c39b
Autor:
Damien Luque Paz, Michael S. Bader, Ronny Nienhold, Shivam Rai, Tiago Almeida Fonseca, Jan Stetka, Hui Hao-Shen, Gabriele Mild-Schneider, Jakob R. Passweg, Radek C. Skoda
Publikováno v:
HemaSphere, Vol 7, Iss 5, p e885 (2023)
Myeloproliferative neoplasms (MPNs) are caused by a somatic gain-of-function mutation in 1 of the 3 disease driver genes JAK2, MPL, or CALR. About half of the MPNs patients also carry additional somatic mutations that modify the clinical course. The
Externí odkaz:
https://doaj.org/article/81859577bfc14bcca1747a3f6ad405a3
Autor:
Melissa Lock, Damien Luque Paz, Nils Hansen, Tiago Almeida Fonseca, MARC Usart, Shivam Rai, Hui Hao-Shen, Gabriele Mild, Stephan Dirnhofer, Radek C. Skoda, Jan Stetka
Publikováno v:
Blood. 140:3876-3877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::639d69471d1918b6fabf2ff3b6ddb3fc
https://doi.org/10.1182/blood-2022-167002
https://doi.org/10.1182/blood-2022-167002
Autor:
Juergen Reuter, Gabriele Mild, Luigi Terracciano, Adam Lowy, Jean-Louis Boulay, Richard Herrmann, Urban Laffer, Magali Lagrange, Christoph Rochlitz
Publikováno v:
International Journal of Cancer. 104:446-449
Chromosomal region 18q21 is frequently deleted in colorectal cancer (CRC) and is associated with poor prognosis. Potential tumor suppressor mechanisms altered by 18q21 deletion include mediation of TGFbeta signaling by SMADs. Following the definition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc57f0b7d6ff4710cedc92ea696332e5
https://doi.org/10.1002/ijc.10908
https://doi.org/10.1002/ijc.10908
Autor:
U. Metzger, Luigi Terracciano, Richard Herrmann, Juergen Reuter, Christoph Mamot, U. Laffer, Christoph Rochlitz, Jean-Louis Boulay, Gabriele Mild
Publikováno v:
British Journal of Cancer
Smad4 is a candidate tumour-suppressor gene identified recently on chromosome 18q21.1. Both alleles are inactivated in nearly one-half of pancreatic carcinomas, but its role in the tumorigenesis of other tumours is still unknown. The aim of this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba540c5cc1d34a5d63e19eca0ce6eabe
https://doi.org/10.1038/sj.bjc.6600733
https://doi.org/10.1038/sj.bjc.6600733
Autor:
Katharina Glatz, Urban Laffer, Jean-Louis Boulay, Gabriele Mild, Luigi Terracciano, J Reuter, Richard Herrmann, Urs Metzger, Christoph Rochlitz, Adam Lowy, Felix Bachmann
Publikováno v:
International Journal of Cancer. 102:254-257
Adjuvant chemotherapy reduces the incidence of distant metastasis and increases survival of patients with colorectal cancer. However, predictive markers are needed to define subsets of patients with stage II and III disease that may benefit from adju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4354e34aacf208552cd0f321beeaf2
https://doi.org/10.1002/ijc.10711
https://doi.org/10.1002/ijc.10711
Autor:
Urban Laffer, Urs Metzger, B. Orth, Christoph Rochlitz, Juergen Reuter, Bernhard Stamm, Magali Lagrange, Richard Herrmann, Sebastiano Martinoli, Adam Lowy, Jean-Louis Boulay, Luigi Terracciano, Gabriele Mild
Publikováno v:
Genes, Chromosomes and Cancer. 31:240-247
Deletions of chromosome band 18q21 appear with very high frequency in a variety of carcinomas, especially in colorectal cancer. Potent tumor suppressor genes located in this region encode transforming growth factor β (TGF-β) signal transducers SMAD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5a5b8a64d0deda1be1131d0d82265b
https://doi.org/10.1002/gcc.1140
https://doi.org/10.1002/gcc.1140
Publikováno v:
Journal of receptor and signal transduction research. 30(6)
Cellular models for the study of the neuropeptide melanin-concentrating hormone (MCH) have become indispensable tools for pharmacological profiling and signaling analysis of MCH and its synthetic analogues. Although expression of MCH receptors is mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a25d7d77971fbf0fecd4b400fd2aa6f
https://pubmed.ncbi.nlm.nih.gov/21083507
https://pubmed.ncbi.nlm.nih.gov/21083507
Autor:
Alex N. Eberle, Gabriele Mild
Publikováno v:
Journal of receptor and signal transduction research. 29(1)
Radiolabeled peptides have become important tools for preclinical cancer research, and in nuclear oncology they serve as diagnostic and more recently also as therapeutic agents. In the latter application, radiolabeled peptides represent a distinct se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e45fbb62c8752437645e52154fd766
https://pubmed.ncbi.nlm.nih.gov/19519167
https://pubmed.ncbi.nlm.nih.gov/19519167
Autor:
Iana, Storojeva, Jean-Louis, Boulay, Karl, Heinimann, Pierluigi, Ballabeni, Luigi, Terracciano, Urban, Laffer, Gabriele, Mild, Richard, Herrmann, Christoph, Rochlitz
Publikováno v:
Oncology reports. 14(1)
Microsatellite instability (MSI) is the phenotypic hallmark of a deficient DNA mismatch-repair system, observed in 10-20% of sporadic colorectal cancers (CRC). Since the prognostic and predictive value of this genetic alteration has been assessed mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f8c5032300187e93d3eee6fdfda07b0
https://pubmed.ncbi.nlm.nih.gov/15944796
https://pubmed.ncbi.nlm.nih.gov/15944796