Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gabriele Meder"'
Autor:
Gabriele Meder, Klaus Doering, Julian Woelcke, Peter Drueckes, Ulrich Hassiepen, Stephan Pritz, Lorenz M. Mayr
Publikováno v:
SLAS Discovery. 16:65-72
We present a novel homogeneous in vitro assay format and apply it to the quantitative determination of the enzymatic activity of a tyrosine kinase. The assay employs a short peptidic substrate containing a single tyrosine and a single probe attached
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071d6bfc9d34da676c005819a73fc7b5
https://doi.org/10.1177/1087057110385817
https://doi.org/10.1177/1087057110385817
Autor:
Renato Baumgartner, Allan D'Arcy, Richard Morse, Christophe Briand, Arnaud Decock, Gabriele Meder, Ulrich Hassiepen, Martin Renatus
Publikováno v:
The Biochemical journal. 423(3)
Neurodegenerative diseases pose one of the most pressing unmet medical needs today. It has long been recognized that caspase-6 may play a role in several neurodegenerative diseases for which there are currently no disease-modifying therapies. Thus it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f8a694f4e9790fd020f33845f5bdea
https://pubmed.ncbi.nlm.nih.gov/19694615
https://pubmed.ncbi.nlm.nih.gov/19694615
Autor:
Lorenz M. Mayr, Manuela Hinnenberger, Gabriele Meder, Ulrich Hassiepen, Klaus Doering, Julian Woelcke
Publikováno v:
Journal of biomolecular screening. 14(1)
Fluorescence lifetime is an intrinsic parameter describing the fluorescence process. Changes in the fluorophore's physicochemical environment can lead to changes in the fluorescence lifetime. When used as the readout in biological assays, it is thoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b95711d6f06bc2aed6881abcb351511
https://pubmed.ncbi.nlm.nih.gov/19171917
https://pubmed.ncbi.nlm.nih.gov/19171917
Autor:
Johannes Ottl, Andreas Boettcher, Damaris Becker, Jutta Blank, Gabriele Meder, Lorenz M. Mayr, Michael Forstner, Lukas Leder, Martin Klumpp
Publikováno v:
Journal of biomolecular screening. 11(6)
This article discusses the development of homogeneous, miniaturized assays for the identification of novel kinase inhibitors from very large compound collections. In particular, the suitability of time-resolved fluorescence resonance energy transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ec6bc9e41cb3a333bf706c02eec08f
https://pubmed.ncbi.nlm.nih.gov/16760365
https://pubmed.ncbi.nlm.nih.gov/16760365