Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gabriele Köllner"'
Autor:
Helga Rübsamen-Schaeff, Andreas Weishaupt, Daniela Paulsen, Niklas Beyersdorf, Sandra Werner, Nelli Wolf, Gabriele Köllner, Thomas Kerkau, Thomas Hünig
Publikováno v:
Journal of Neuroimmunology. 282:63-72
Targeting regulatory T cells (Treg cells) with interleukin-2 (IL-2) constitutes a novel therapeutic approach for autoimmunity. As anti-cancer therapy with IL-2 has revealed substantial toxicities a mutated human IL-2 molecule, termed AIC284 (formerly
Autor:
Stefan Jung, Klaus V. Toyka, Stefanie Gaupp, Thomas Korn, Gabriele Köllner, Hans-Peter Hartung
Publikováno v:
Journal of Neuroscience Research. 75:524-535
A new and biphasic form of experimental autoimmune neuritis (EAN) is described in dark agouti rats (DA rats) and is inducible by a single immunization with bovine peripheral nerve myelin (BPM) in complete Freund's adjuvant (DA-EAN). Animals develop a
Autor:
Stefan, Jung, Stefanie, Gaupp, Thomas, Korn, Gabriele, Köllner, Hans-Peter, Hartung, Klaus V, Toyka
Publikováno v:
Journal of neuroscience research. 75(4)
A new and biphasic form of experimental autoimmune neuritis (EAN) is described in dark agouti rats (DA rats) and is inducible by a single immunization with bovine peripheral nerve myelin (BPM) in complete Freund's adjuvant (DA-EAN). Animals develop a
Autor:
Klaus V. Toyka, Stefan Jung, Irena Girkontaite, Klaus-Dieter Fischer, Thomas Korn, Gabriele Köllner
Publikováno v:
Journal of neuroimmunology. 139(1-2)
Mice that lack the guanine nucleotide exchange factor (GEF) Vav1 exhibit particular defects in antigen-triggered T cell activation but may have an autoreactive T cell repertoire due to impaired intra-thymic negative selection. MOG(35-55)-induced expe
Autor:
Stefan Jung, Hans-Peter Hartung, Torsten Donhauser, Gabriele Köllner, Klaus V. Toyka, Jürgen Zielasek
Publikováno v:
Journal of neuroimmunology. 68(1-2)
Experimental autoimmune encephalomyelitis (EAE) in Lewis rats, an animal model mimicking some aspects of multiple sclerosis, was treated with the type IV-specific phosphodiesterase inhibitor Rolipram. Actively induced EAE evoked by immunization with