Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Gabriele Jäger"'
Autor:
Jovica Ninkovic, Gábor Heimann, Jesica Frik, Tjasa Lepko, Gabriele Jäger, Luisa Lange Canhos, Magdalena Götz, Swetlana Sirko
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Cereb. Cortex 27, 1-16 (2017)
Universidad Nacional de La Plata
instacron:UNLP
Cereb. Cortex 27, 1-16 (2017)
Aging leads to adverse outcomes after traumatic brain injury. The mechanisms underlying these defects, however, are not yet clear. In this study, we found that astrocytes in the aged post-traumatic cerebral cortex develop a significantly reduced prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297387118877ef8db567c85c09f74d76
http://sedici.unlp.edu.ar/handle/10915/87440
http://sedici.unlp.edu.ar/handle/10915/87440
Autor:
Martin Liebetrau, Dorothe Burggraf, Gerhard F. Hamann, Helge K. Martens, Gabriele Jäger, Nathalie Wunderlich, Martin Dichgans
Publikováno v:
European Journal of Neuroscience. 22:273-277
Focal cerebral ischemia leads to the gradual disruption of the extracellular matrix. A key role in the turnover of the extracellular matrix is played by the system of matrix metalloproteinases (MMPs). In this study we describe changes of the MMP indu
Publikováno v:
European Journal of Neuroscience. 20:2903-2908
The aim of this study was to investigate the effects of different doses of exogenous recombinant human tissue plasminogen activator (rt-PA) on the endogenous cerebral plasminogen-plasmin system in focal ischemia in rats. Ischemia was induced using th
Publikováno v:
Thrombosis and Haemostasis. 89:1072-1080
SummaryWhile recombinant tissue plasminogen activator (rt-PA) is successfully used in human ischemic stroke, it may also cause hemorrhagic complications. Animal experiments have shown that hemorrhages are related to microvascular basal lamina damage.
Autor:
Martin Liebetrau, Christian U.A. Kloss, Gerhard F. Hamann, G. Bültemeier, Natalie Wunderlich, Gabriele Jäger, Dorothe Burggraf, Thomas Pfefferkorn, Helge K. Martens
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 22:526-533
To define the location and extent of microvascular damage of the basal lamina after cerebral ischemia and reperfusion in rats, the authors subjected animals (n = 16) to 3 hours of focal cerebral ischemia and 24 hours of reperfusion using the suture m
Autor:
Stephan Form, Gabriele Jäger
Publikováno v:
Controlling. 13:103-112
Autor:
Moritz Gröger, Gabriele Jäger, Dorothe Burggraf, Gerhard F. Hamann, Milan R. Vosko, Martin Liebetrau, Nathalie Wunderlich, Nikolaus Plesnila
Publikováno v:
Neurological research. 28(2)
Focal cerebral ischemia is responsible for alterations of vascular permeability, and the loss of microvascular integrity is a primary source of subsequent hemorrhages. We evaluated the influence of different durations of ischemia and reperfusion on i
Autor:
Dorothe, Burggraf, Helge K, Martens, Nathalie, Wunderlich, Gabriele, Jäger, Gerhard F, Hamann
Publikováno v:
The European journal of neuroscience. 20(11)
The aim of this study was to investigate the effects of different doses of exogenous recombinant human tissue plasminogen activator (rt-PA) on the endogenous cerebral plasminogen-plasmin system in focal ischemia in rats. Ischemia was induced using th
Autor:
Gerhard F. Hamann, Wolfgang Linz, Martin Liebetrau, Gabriele Jäger, Dorothe Burggraf, Nathalie Wunderlich
Publikováno v:
Neuroscience letters. 376(3)
The spontaneously hypertensive stroke-prone rat (SHR-SP) is an experimental model of malignant hypertension which lead to secondary alterations of the extracellular matrix. Our aim was to determine ACE-inhibitor related changes of proteases involved
Autor:
Martin Liebetrau, Nathalie Wunderlich, Gabriele Jäger, Helge K. Martens, Michael A DeGeorgia, Dorothe Burggraf, Gerhard F. Hamann, Derk W. Krieger
Publikováno v:
Stroke. 35(3)
Background and Purpose— Microvascular basal lamina damage occurs after cerebral ischemia and is important for the development of hemorrhage. The aim of this study was to determine whether hypothermia could maintain microvascular integrity in ischem