Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gabriele Floris"'
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is hampered by perseverant drug cravings that may persist for months after cessation of drug use. Drug cravings can intensify during the abstinence period,
Externí odkaz:
https://doaj.org/article/97fa04348a924de2861421216d99aab0
Publikováno v:
Brain Research Bulletin, Vol 181, Iss , Pp 157-166 (2022)
Pramipexole is a potent agonist of D3 and D2 dopamine receptors, currently approved for clinical use in Parkinson's disease (PD) and restless leg syndrome. Several studies have shown that pramipexole significantly increases the risk of pathological g
Externí odkaz:
https://doaj.org/article/2a03e2daf6574d92985d4c7d6e23ef3b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/c13cd6382ad2469aabd4c470baf62c67
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Patients with opioid use disorder experience high rates of relapse during recovery, despite successful completion of rehabilitation programs. A key factor contributing to this problem is the long-lasting nature of drug-seeking behavior assoc
Externí odkaz:
https://doaj.org/article/642541cecae04f93bdf2c08c29bb4dea
Autor:
Gabriele Floris, Gino Paolo Asuni, Giuseppe Talani, Francesca Biggio, Maria Giuseppina Pisu, Mary Tresa Zanda, Liliana Contu, Elisabetta Maciocco, Mariangela Serra, Paolo Follesa
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Gamma-aminobutyric acid type B receptor (GABABR) has been extensively involved in alcohol use disorders; however, the mechanisms by which this receptor modulates alcohol drinking behavior remain murky. In this study, we investigate alcohol consumptio
Externí odkaz:
https://doaj.org/article/f10a96a423e34f8c82acf87c2c4938ba
Autor:
Gabriele Floris, Aria Gillespie, Mary Tresa Zanda, Konrad R. Dabrowski, Stephanie E. Sillivan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1453 (2022)
The number of drug overdose deaths involving opioids continues to rise in the United States. Many patients with opioid use disorder (OUD) that seek treatment still experience relapse. Perseverant opioid seeking behaviors represent a major challenge t
Externí odkaz:
https://doaj.org/article/5a245b1e0feb41ce80070752d2c886c8
Autor:
Sean C. Godar, Roberto Cadeddu, Gabriele Floris, Laura J. Mosher, Zhen Mi, David P. Jarmolowicz, Simona Scheggi, Alicia A. Walf, Carolyn J. Koonce, Cheryl A. Frye, Nancy A. Muma, Marco Bortolato
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 749 (2019)
Finasteride (FIN) is the prototypical inhibitor of steroid 5α-reductase (5αR), the enzyme that catalyzes the rate-limiting step of the conversion of progesterone and testosterone into their main neuroactive metabolites. FIN is clinically approved f
Externí odkaz:
https://doaj.org/article/baf95fecf4604756a46e4525aef8e736
Autor:
Sebastiano Banni, Gianfranca Carta, Elisabetta Murru, Lina Cordeddu, Elena Giordano, Francesco Marrosu, Monica Puligheddu, Gabriele Floris, Gino Paolo Asuni, Angela Letizia Cappai, Silvia Deriu, Paolo Follesa
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44813 (2012)
Among the manifold effects of vagus nerve stimulation (VNS) delivered as an add-on treatment to patients with drug-resistant epilepsy, a moderate loss of body weight has been observed in some individuals. We have now investigated this effect in rats.
Externí odkaz:
https://doaj.org/article/da0f8e666d7c4d679fe0b76b17350dcd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Patients with opioid use disorder experience high rates of relapse during recovery, despite successful completion of rehabilitation programs. A key factor contributing to this problem is the long-lasting nature of drug-seeking behavior associated wit
Autor:
Simona Scheggi, Gabriele Floris, Marco Orrù, Beth Levant, Hunter J. Strathman, Marco Bortolato
Publikováno v:
European Neuropsychopharmacology. 32:104-119
Pramipexole (PPX) is a D2 and D3 dopamine receptor agonist approved for clinical use, which is associated with a higher risk of impulse-control disorders. Using a rat model, we recently found that low doses of the monoamine-depleting agent reserpine