Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gabriele Brockerhoff"'
Autor:
Julia Hartmann, Noah Henschel, Kristina Bartmann, Arif Dönmez, Gabriele Brockerhoff, Katharina Koch, Ellen Fritsche
Publikováno v:
Cells, Vol 12, Iss 9, p 1270 (2023)
The currently accepted methods for neurotoxicity (NT) testing rely on animal studies. However, high costs and low testing throughput hinder their application for large numbers of chemicals. To overcome these limitations, in vitro methods are currentl
Externí odkaz:
https://doaj.org/article/0076fd20e90640a7b6cefaf6e71eb1b7
Autor:
Laura Nimtz, Julia Hartmann, Julia Tigges, Stefan Masjosthusmann, Martin Schmuck, Eike Keßel, Stephan Theiss, Karl Köhrer, Patrick Petzsch, James Adjaye, Claudia Wigmann, Dagmar Wieczorek, Barbara Hildebrandt, Farina Bendt, Ulrike Hübenthal, Gabriele Brockerhoff, Ellen Fritsche
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
Neurotoxicity is mediated by a variety of modes-of-actions leading to disturbance of neuronal function. In order to screen larger numbers of compounds for their neurotoxic potential, in vitro functional neuronal networks (NN) might be helpful tools.
Externí odkaz:
https://doaj.org/article/6ce21a344da041f7ac23989029624edd
Autor:
Constanze Uhlmann, Ann‐Christin Nickel, Daniel Picard, Andrea Rossi, Guanzhang Li, Barbara Hildebrandt, Gabriele Brockerhoff, Farina Bendt, Ulrike Hübenthal, Michael Hewera, Hans‐Jakob Steiger, Dagmar Wieczorek, Aristoteles Perrakis, Wei Zhang, Marc Remke, Katharina Koch, Julia Tigges, Roland S. Croner, Ellen Fritsche, Ulf D. Kahlert
Publikováno v:
Biotechnology Journal. 17:2100693
Limitations in genetic stability and recapitulating accurate physiological disease properties challenge the utility of patient-derived (PD) cancer models for reproducible and translational research. A portfolio of isogenic human induced pluripotent s
Autor:
Ulrike Hübenthal, Dagmar Wieczorek, Ellen Fritsche, Farina Bendt, James Adjaye, Stefan Masjosthusmann, Julia Hartmann, Stephan Theiss, Gabriele Brockerhoff, Julia Tigges, Barbara Hildebrandt, Karl Köhrer, Martin Schmuck, Laura Nimtz, Eike Keßel, Claudia Wigmann, Patrick Petzsch
Publikováno v:
Stem Cell Research, Vol 45, Iss, Pp-(2020)
Neurotoxicity is mediated by a variety of modes-of-actions leading to disturbance of neuronal function. In order to screen larger numbers of compounds for their neurotoxic potential, in vitro functional neuronal networks (NN) might be helpful tools.
Publikováno v:
Frontiers in Cellular Neuroscience. 12