Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Gabriele, Niedermann"'
Autor:
Nanhao Yin, Xintong Li, Xuanwei Zhang, Shaolong Xue, Yu Cao, Gabriele Niedermann, You Lu, Jianxin Xue
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-50 (2024)
Abstract Immunotherapy represented by anti-PD-(L)1 and anti-CTLA-4 inhibitors has revolutionized cancer treatment, but challenges related to resistance and toxicity still remain. Due to the advancement of immuno-oncology, an increasing number of nove
Externí odkaz:
https://doaj.org/article/16b1901039d0420db4a3a0620183c418
Autor:
Kateryna Onyshchenko, Ren Luo, Elena Guffart, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9611116748194752b53637c4fb8e26f4
Autor:
Kateryna Onyshchenko, Ren Luo, Elena Guffart, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Combination of radiation therapy (RT) with immune checkpoint blockade can enhance systemic anti-tumor T cell responses. Here, using two mouse tumor models, we demonstrate that adding long-acting CD122-directed IL-2 complexes (IL-2c) to RT/an
Externí odkaz:
https://doaj.org/article/f9e6a4f9f7cc441cbb1bcc250a712ba3
Autor:
Eleni Gkika, Elke Firat, Sonja Adebahr, Erika Graf, Ilinca Popp, Gianluca Radicioni, Simon S. Lo, Ursula Nestle, Nils H. Nicolay, Gabriele Niedermann, Dan G. Duda, Anca-L. Grosu
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract We performed a prospective study of circulating immune cell changes after stereotactic body radiotherapy (SBRT) in 50 early-stage NSCLC patients. We found no significant increase in CD8+ cytotoxic T lymphocytes at first follow-up (the primar
Externí odkaz:
https://doaj.org/article/537504b77a584db7a48979724411a17a
Autor:
Simone Gaedicke, Elke Firat, Gabriele Niedermann, Liqun Wang, Ren Luo, Kateryna Onyshchenko, Xi Rao, Meidan Wang, Beatrice Menz, Anca-Ligia Grosu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Localized radiotherapy (RT) can cause a T cell-mediated abscopal effect on non-irradiated tumor lesions, especially in combination with immune checkpoint blockade. However, this effect is still clinically rare and improvements are highly d
Externí odkaz:
https://doaj.org/article/133823e568944a20bf45d927283be209
Autor:
Simone Gaedicke, Gabriele Niedermann, Anne Grote, Friedrich Feuerhake, Eva Oswald, Kanstantsin Lashuk, Daniel Bug, Nassim Bouteldja, Dorothee Lenhard, Anne Löhr, Anke Behnke, Volker Knauff, Anna Edinger, Kerstin Klingner, Dorit Merhof, Julia Schueler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/6d293a6cd46e42e59c4af0d350d0d410
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Immunogenic radiotherapy (RT) can act synergistically with immune checkpoint blockers (ICBs). However, alternatives are needed for non-responding patients and those with pre-existing or ICB-induced autoimmune symptoms. Combination
Externí odkaz:
https://doaj.org/article/e457fde1ed04482cb15845f9bd6b08c0
Autor:
Jiaxing Tang, Yan Zou, Long Li, Fengping Lu, Hongtao Xu, Pengxuan Ren, Fang Bai, Gabriele Niedermann, Xuekai Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Chimeric antigen receptor (CAR) T cells are powerful in eradicating hematological malignancies, but their efficacy is limited in treating solid tumors. One of the barriers is the immunosuppressive response induced by immunomodulatory signaling pathwa
Externí odkaz:
https://doaj.org/article/30632ec5ca7a420baa6f2131cc3aaef1
Autor:
Gabriele Niedermann, Elke Firat, Anca-Ligia Grosu, Simone Gaedicke, Liqun Wang, Kateryna Onyshchenko, Ren Luo
Potency of platinum derivatives to facilitate the RT-induced abscopal effect in the C51 colon carcinoma model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487f343f20bf4f779b9324a987cf9b93
https://doi.org/10.1158/1078-0432.22489353
https://doi.org/10.1158/1078-0432.22489353
Autor:
Gabriele Niedermann, Elke Firat, Anca-Ligia Grosu, Simone Gaedicke, Liqun Wang, Kateryna Onyshchenko, Ren Luo
P values for Spearman's correlation coefficient and hazard ratio data shown in Table S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac3ba4454c2ac7014466c693c73e930
https://doi.org/10.1158/1078-0432.22489320
https://doi.org/10.1158/1078-0432.22489320