Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Gabriele, Costantino"'
Publikováno v:
Frontiers in Natural Products, Vol 3 (2024)
Natural products have been used since ancient times to treat various ailments and have been recognized for many years as a source of therapeutic agents and structural diversity. Plant-derived products have thus served as dietary components but also t
Externí odkaz:
https://doaj.org/article/d9f1112adc6f44a3bb26919f0a7365cd
Autor:
Elisabetta Miraldi, Giorgio Cappellucci, Giulia Baini, Elia Silvia Pistone, Marika Allodi, Gabriele Costantino, Chiara Spaggiari, Marco Biagi
Publikováno v:
Plants, Vol 13, Iss 19, p 2734 (2024)
Knowledge of the chemical composition of propolis is crucial for understanding the characteristics of products of different origins, but also for quality control and regulatory purposes. To date, official monographs or official analyses that allow re
Externí odkaz:
https://doaj.org/article/34162a6de9e34deea4e649a374a4f779
Autor:
Simone Giovannuzzi, Chad S. Hewitt, Alessio Nocentini, Clemente Capasso, Gabriele Costantino, Daniel P. Flaherty, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 666-671 (2022)
The α-class carbonic anhydrases (CAs, EC 4.2.1.1) from the bacterial pathogens Neisseria gonorrhoeae (NgCAα) and Vibrio cholerae (VchCAα) were investigated for their inhibition by a panel of phenols and phenolic acids. Mono-, di- and tri-substitut
Externí odkaz:
https://doaj.org/article/ef33c490e1294667bda40aef295498e2
Autor:
Andrea Angeli, Marta Ferraroni, Fabrizio Carta, Cécile Häberli, Jennifer Keiser, Gabriele Costantino, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1479-1494 (2022)
The almost empty armamentarium to treat schistosomiasis, a neglected parasitic disorder caused by trematode flatworms of the genus Schistosoma, except Praziquantel (PZQ), urged to find new alternatives to fight this infection. Carbonic Anhydrase from
Externí odkaz:
https://doaj.org/article/0d1fc72355e544a085b8deb92c83d2c0
Autor:
Fulvio Tartara, Daniele Armocida, Diego Garbossa, Francesco Meli, Gabriele Costantino, Fabio Cofano, Natale Francaviglia
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
BackgroundVertebral augmentation procedures (VAPs) are used in cases of persistent and unresponsive pain in patients with vertebral compression fractures (VCFs). Although VAPs are considered a safe procedure providing quick pain relief and improved p
Externí odkaz:
https://doaj.org/article/5eefd1a98b084cf78e2a2f7dede7a8ab
Autor:
Thierry Habyarimana, Alexis Nshimiyimana, William Niyonzima, Janvere Kankindi, Cedrick Izere, Chiara Spaggiari, Gabriele Costantino
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 10, p e0002487 (2023)
COVID-19 is mainly described as endothelial dysfunction, and due to the bidirectional link between oxidative stress and endothelial dysfunction, we initiated a program directed to the evaluation of the oxidative status of the population of Rwanda by
Externí odkaz:
https://doaj.org/article/dad46d54715f4e5ebfce9f8da2a1d64e
Autor:
Marialaura Pavone, Samanta Raboni, Marialaura Marchetti, Giannamaria Annunziato, Stefano Bettati, Bianca Papotti, Cinzia Marchi, Emanuele Carosati, Marco Pieroni, Barbara Campanini, Gabriele Costantino
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100443- (2022)
The development of the so-called antibiotic adjuvants as inhibitors of non-essential targets represents an innovative and attractive approach to counteract antimicrobial resistance (AMR). Most bacteria rely on the reductive sulfate assimilation pathw
Externí odkaz:
https://doaj.org/article/f9352bcf777d4f8cb3ed1438d8063420
Autor:
Chiara Spaggiari, Giannamaria Annunziato, Costanza Spadini, Sabrina Lucia Montanaro, Mattia Iannarelli, Clotilde Silvia Cabassi, Gabriele Costantino
Publikováno v:
Molecules, Vol 28, Iss 5, p 2134 (2023)
Azelaic Acid (AzA) is a 9-carbon atom dicarboxylic acid, with numerous pharmacological uses in dermatology. Its effectiveness in papulopustular rosacea and acne vulgaris, among other dermatological disorders such as keratinization and hyper-pigmentat
Externí odkaz:
https://doaj.org/article/10a64d997dec4796ba167f9ea93b789b
Autor:
Chiara Spaggiari, Laura Righetti, Costanza Spadini, Giannamaria Annunziato, Aimable Nsanzurwimo, Clotilde Silvia Cabassi, Renato Bruni, Gabriele Costantino
Publikováno v:
Plants, Vol 12, Iss 3, p 482 (2023)
The comprehensive identification of secondary metabolites represents a fundamental step for the assessment of bioactivities and pharmacological properties of traditional herbal drugs. Rumex usambarensis (Dammer) Dammer has been described as a multipu
Externí odkaz:
https://doaj.org/article/e74fdcb503f2495f92a66f2ebf1c5df0
Autor:
Joana Magalhães, Nina Franko, Giannamaria Annunziato, Marco Pieroni, Roberto Benoni, Anna Nikitjuka, Andrea Mozzarelli, Stefano Bettati, Anna Karawajczyk, Aigars Jirgensons, Barbara Campanini, Gabriele Costantino
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 31-43 (2019)
The lack of efficacy of current antibacterials to treat multidrug resistant bacteria poses a life-threatening alarm. In order to develop enhancers of the antibacterial activity, we carried out a medicinal chemistry campaign aiming to develop inhibito
Externí odkaz:
https://doaj.org/article/a7f454e5900149429f6d3c19ae6529c0