Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gabriela de Assis Burle-Caldas"'
Autor:
Ana Maria Murta Santi, Juliana Martins Ribeiro, João Luís Reis-Cunha, Gabriela de Assis Burle-Caldas, Isabella Fernandes Martins Santos, Paula Alves Silva, Daniela de Melo Resende, Daniella Castanheira Bartholomeu, Santuza Maria Ribeiro Teixeira, Silvane Maria Fonseca Murta
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 10 (2022)
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a serious chronic parasitic disease, currently treated with Nifurtimox (NFX) and Benznidazole (BZ). In addition to high toxicity, these drugs have low healing efficacy, especially in the c
Externí odkaz:
https://doaj.org/article/8959fab4bb0846448762a5eaf6da1057
Autor:
Tiago de Paula Marcelino, Angela Maria Fala, Matheus Monteiro da Silva, Normanda Souza-Melo, Amaranta Muniz Malvezzi, Angélica Hollunder Klippel, Martin Zoltner, Norma Padilla-Mejia, Samantha Kosto, Mark C. Field, Gabriela de Assis Burle Caldas, Santuza Maria Ribeiro Teixeira, Rafael Miguez Couñago, Katlin Brauer Massirer, Sergio Schenkman
Publikováno v:
Journal of Biological Chemistry. :104857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5e45dbb203e4d3d86a0b6030b5093aa
https://doi.org/10.1016/j.jbc.2023.104857
https://doi.org/10.1016/j.jbc.2023.104857
Autor:
Ricardo T. Gazzinelli, Sergio Schenkman, Júlia Teixeira de Castro, Milton C. A. Pereira, Gabriela de Assis Burle Caldas, Nailma S. A. dos Santos, Santuza M. R. Teixeira, Viviane Grazielle Silva
Publikováno v:
Annals of the V ISI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02e6c1d983038e85c7571ab083be79e
https://doi.org/10.35259/isi.2021_46702
https://doi.org/10.35259/isi.2021_46702
Autor:
Santuza M. R. Teixeira, Alexandre V. Machado, Ricardo T. Gazzinelli, Gabriela de Assis Burle Caldas, Júlia Teixeira de Castro, Kimberly Freitas Cardoso, Ana Paula F. Gonçalves, Daniel Doro
Publikováno v:
Annals of the V ISI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77995c215278ee1d6d4ebafac3072ced
https://doi.org/10.35259/isi.2021_46734
https://doi.org/10.35259/isi.2021_46734
Autor:
Melissa Soares-Simões, Gabriela de Assis Burle-Caldas, Wanderson D. DaRocha, Santuza M. R. Teixeira, Laiane Lemos-Pechnicki
Publikováno v:
International Journal for Parasitology. 48:591-596
CRISPR/Cas9 technology has been used to edit genomes in a variety of organisms. Using the GP72 gene as a target sequence, we tested two distinct approaches to generate Trypanosoma cruzi knockout mutants using the Cas9 nuclease and in vitro transcribe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d427329eefaa9eadd7f23d5eb63793c
https://doi.org/10.1016/j.ijpara.2018.02.002
https://doi.org/10.1016/j.ijpara.2018.02.002
Autor:
Melissa Soares-Simões, Viviane Grazielle-Silva, Isabel Roditi, Santuza M. R. Teixeira, Wanderson D. DaRocha, Gabriela Schumann Burkard, Gabriela de Assis Burle-Caldas
Publikováno v:
Molecular and Biochemical Parasitology. 212:28-32
Gene function studies in Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, have been hindered by the lack of efficient genetic manipulation protocols. In most organisms, insertion and deletion of DNA fragments in the genome are de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe04be947aea500062a6370da4475d5e
https://doi.org/10.1016/j.molbiopara.2017.01.002
https://doi.org/10.1016/j.molbiopara.2017.01.002
Autor:
Ester Roffê, Rosa Maria Esteves Arantes, Caroline Junqueira, Carlos A Toro Acevedo, Santuza M. R. Teixeira, Gabriela de Assis Burle-Caldas, Ricardo T. Gazzinelli, Helton C. Santiago, Bruno Galvão-Filho, Bruna M. Valente
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Several antigens from Trypanosoma cruzi, the causative agent of Chagas disease (CD), contain amino acid repeats identified as targets of the host immune response. Ribosomal proteins containing an Ala, Lys, Pro-rich repeat domain are among the T. cruz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6d95dec781d052a4eb5bd1a715b939
https://doi.org/10.3389/fmicb.2017.02188
https://doi.org/10.3389/fmicb.2017.02188
Publikováno v:
Repositório Institucional da UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico A manipulação genética em tripanosomatídeos é uma ferramenta essencial para estudo desses organismos, muitos deles, agentes causadores de importantes doenças humanas e veter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3056::24b3cf75b4003e9f7f4a504b7c43b957
Autor:
Santuza M. R. Teixeira, Letícia Adejani Laibida, Viviane Grazielle-Silva, Wanderson D. DaRocha, Gabriela de Assis Burle-Caldas
Publikováno v:
Molecular and biochemical parasitology. 203(1-2)
Trypanosoma cruzi is a protozoan parasite that causes Chagas disease, an illness that affects 6-7 million people and for which there is no effective drug therapy or vaccine. The publication of its complete genome sequence allowed a rapid advance in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e985aeb4bc702ed97edcf7522febe4
https://pubmed.ncbi.nlm.nih.gov/26523948
https://pubmed.ncbi.nlm.nih.gov/26523948
Autor:
Patrícia R. Araújo, Daniella Castanheira Bartholomeu, Wanderson D. DaRocha, Santuza M. R. Teixeira, Gabriela de Assis Burle-Caldas, Rosiane A. Silva-Pereira
Publikováno v:
Parasitology international. 60(2)
In trypanosomatids, transcription is polycistronic and gene expression control occurs mainly at the post-transcriptional level. To investigate the role of sequences present in the 3′UTR of stage-specific mRNAs of Trypanosoma cruzi, we generated a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1ffb6bbeeb54bdcc4258ce24a0a401
https://pubmed.ncbi.nlm.nih.gov/21277385
https://pubmed.ncbi.nlm.nih.gov/21277385