Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Gabriela Vera-Lozada"'
1
Akademický článek
Molecular aspects of Chikungunya virus infections in cancer patients
Autor: Débora Familiar-Macedo, Bianca Ervatti Gama, Vanessa Erichsen Emmel, Gabriela Vera-Lozada, Eliana Abdelhay, Ianick Souto Martins, Rocio Hassan
Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 117 (2022)
BACKGROUND Chikungunya virus (CHIKV) is an arbovirus that can cause chronic and debilitating manifestations. The first autochthonous case in Rio de Janeiro state was diagnosed in 2015, and an outbreak was declared in 2016. OBJECTIVE The aim of this w
Externí odkaz: https://doaj.org/article/fa9456bbac6440a99c7bf88f095448f6
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2
Akademický článek
Revisiting the Tissue Microenvironment of Infectious Mononucleosis: Identification of EBV Infection in T Cells and Deep Characterization of Immune Profiles
Autor: Mário Henrique M. Barros, Gabriela Vera-Lozada, Priscilla Segges, Rocio Hassan, Gerald Niedobitek
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
To aid understanding of primary EBV infection, we have performed an in depth analysis of EBV-infected cells and of local immune cells in tonsils from infectious mononucleosis (IM) patients. We show that EBV is present in approximately 50% of B-cells
Externí odkaz: https://doaj.org/article/44cf3fe5704b4dafa4138b81836d60b1
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3
Akademický článek
Interleukin 10 (IL10) proximal promoter polymorphisms beyond clinical response in classical Hodgkin lymphoma: Exploring the basis for the genetic control of the tumor microenvironment
Autor: Gabriela Vera-Lozada, Carolina Minnicelli, Priscilla Segges, Gustavo Stefanoff, Flavia Kristcevic, Joaquin Ezpeleta, Elizabeth Tapia, Gerald Niedobitek, Mário Henrique M. Barros, Rocio Hassan
Publikováno v: OncoImmunology, Vol 7, Iss 5 (2018)
Interleukin-10 (IL10) is an immune regulatory cytokine. Single nucleotide polymorphisms (SNPs) in IL10 promoter have been associated with prognosis in adult classical Hodgkin lymphoma (cHL). We analyzed IL10 SNPs −1082 and −592 in respect of ther
Externí odkaz: https://doaj.org/article/843e6e7b40c946a988e416fd87f7be58
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4
Akademický článek
Targeting Hodgkin and Reed–Sternberg Cells with an Inhibitor of Heat-Shock Protein 90: Molecular Pathways of Response and Potential Mechanisms of Resistance
Autor: Priscilla Segges, Stephany Corrêa, Bárbara Du Rocher, Gabriela Vera-Lozada, Flavia Krsticevic, Debora Arce, Cinthya Sternberg, Eliana Abdelhay, Rocio Hassan
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 3, p 836 (2018)
Classical Hodgkin lymphoma (cHL) cells overexpress heat-shock protein 90 (HSP90), an important intracellular signaling hub regulating cell survival, which is emerging as a promising therapeutic target. Here, we report the antitumor effect of celastro
Externí odkaz: https://doaj.org/article/170a1595ffe94450915176066c13ed42
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5
Akademický článek
Macrophage polarization reflects T cell composition of tumor microenvironment in pediatric classical Hodgkin lymphoma and has impact on survival.
Autor: Mário H M Barros, Priscilla Segges, Gabriela Vera-Lozada, Rocio Hassan, Gerald Niedobitek
Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0124531 (2015)
Macrophages have been implicated in the pathogenesis of classical Hodgkin lymphoma (cHL) and have been suggested to have a negative impact on outcome. Most studies addressing the role of macrophages in cHL have relied on identification of macrophages
Externí odkaz: https://doaj.org/article/fe5882a79a13405b82e0d7614fcfa1c7
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6
Pathway-focused gene expression profiles and immunohistochemistry detection identify contrasting association of caspase 3 (CASP3) expression with prognosis in pediatric classical Hodgkin lymphoma
Autor: Claudio Gustavo Stefanoff, Gerald Niedobitek, Priscilla Segges, Gabriela Vera-Lozada, Mário Henrique M. Barros, Rocio Hassan
Publikováno v: Hematological Oncology. 36:663-670
The search for clinically relevant molecular markers in classical Hodgkin lymphoma (cHL) is hampered by the histopathological complexity of the disease, resulting from the admixture of a small number of neoplastic Hodgkin and Reed-Sternberg (H-RS) ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5679418d9f111a85d1df787af8548d12
https://doi.org/10.1002/hon.2523
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9
Targeting hodgkin and reed–sternberg cells with an inhibitor of heat-shock protein 90: Molecular pathways of response and potential mechanisms of resistance
Autor: Rocio Hassan, Gabriela Vera-Lozada, Débora Pamela Arce, Stephany Corrêa, Flavia Krsticevic, Priscilla Segges, Bárbara Du Rocher, Eliana Abdelhay, Cinthya Sternberg
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 3, p 836 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
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International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 3; Pages: 836
Classical Hodgkin lymphoma (cHL) cells overexpress heat-shock protein 90 (HSP90), an important intracellular signaling hub regulating cell survival, which is emerging as a promising therapeutic target. Here, we report the antitumor effect of celastro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8ea7ff47bdfe9b2114f2ce4f86d62d
http://www.mdpi.com/1422-0067/19/3/836
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10
Analysis of biological and technical variability in gene expression assays from formalin-fixed paraffin-embedded classical Hodgkin lymphomas
Autor: Vilberto Stocchi, Mário Henrique M. Barros, Davide Sisti, Gabriela Vera-Lozada, Vanesa Scholl, Rocio Hassan, Michele Guescini, Claudio Gustavo Stefanoff
Publikováno v: Experimental and Molecular Pathology. 97:433-439
Formalin-fixed paraffin-embedded (FFPE) tissues are invaluable sources of biological material for research and diagnostic purposes. In this study, we aimed to identify biological and technical variability in RT-qPCR TaqMan® assays performed with FFP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c7be9ca8c0661ef54c109580dd6423
https://doi.org/10.1016/j.yexmp.2014.09.014
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