Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5)

Autor: Adam J. Pearson, Paul Fullwood, Gabriela Toro Tapia, Ian Prise, Michael P. Smith, Qiuping Xu, Allan Jordan, Emanuele Giurisato, Alan J. Whitmarsh, Chiara Francavilla, Cathy Tournier

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 3, p 929 (2020)

The extracellular signal-regulated protein kinase 5 (ERK5) is a non-redundant mitogen-activated protein kinase (MAPK) that exhibits a unique C-terminal extension which comprises distinct structural and functional properties. Here, we sought to elucid

Externí odkaz: https://doaj.org/article/3fa2fea6c02c4545a61454f2daed1a59

Primary cilium remodeling mediates a cell signaling switch in differentiating neurons

Autor: Raman M. Das, Gabriela Toro-Tapia

Publikováno v: Toro, G & Das, R 2020, ' Primary cilium remodeling mediates a cell signaling switch in differentiating neurons ', Science Advances . https://doi.org/10.1126/sciadv.abb0601
Toro-Tapia, G & Das, R 2020, ' Primary cilium remodelling mediates a cell signalling switch in differentiating neurons ', Science Advances, vol. 6, no. 21 . https://doi.org/10.1126/sciadv.abb0601
Toro, G & Das, R 2020, ' Primary cilium remodeling mediates a cell signaling switch in differentiating neurons ', Science Advances, vol. 6, no. 21, EABB0601 . https://doi.org/10.1126/sciadv.abb0601
Science Advances

Newborn neurons assemble a new primary cilium, leading to a change in the mode of Shh signaling that now directs axon extension.
Cellular differentiation leads to the formation of specialized cell types and complex morphological variations. Ofte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645743b9b049a006c0f10c1a3941b264
https://www.research.manchester.ac.uk/portal/en/publications/primary-cilium-remodeling-mediates-a-cell-signaling-switch-in-differentiating-neurons(e9e0347a-d0d5-411b-86d7-f37f80dfeaa4).html

Expression profiles of the Gα subunits during Xenopus tropicalis embryonic development

Autor: Jaime Fuentealba, Soraya Villaseca, Cecilia Arriagada, Juan I Leal, María Victoria Hinrichs, Gabriela Toro-Tapia, Teresa Caprile, Juan Olate, Andréa Beyer, Alejandro Maureira, Marion Rodriguez, Marcela Torrejón

Publikováno v: Gene Expression Pattern
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Heterotrimeric G protein signaling plays major roles during different cellular events. However, there is a limited understanding of the molecular mechanisms underlying G protein control during embryogenesis. G proteins are highly conserved and can be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417e362dc6da0484113af7e99c4e9eb4
https://doi.org/10.1016/j.gep.2016.09.001

Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration

Autor: Andréa Beyer, Sylvain Marcellini, Juan Olate, Marcela Torrejón, Gabriela Toro-Tapia, Juan Pablo Henríquez, Roberto Mayor, Jaime Fuentealba, Cecilia Arriagada, Lester Riquelme, María Victoria Hinrichs, Teresa Caprile

Publikováno v: DEVELOPMENTAL BIOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

The neural crest (NC) is a transient embryonic structure induced at the border of the neural plate. NC cells extensively migrate towards diverse regions of the embryo, where they differentiate into various derivatives, including most of the craniofac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacad58be8685da0173d67a7d538dbd0

XTRIC-8, a protein required for proper neural crest formation

Autor: Marcela Torrejón, Gabriela Toro-Tapia, Cecilia Arriagada, Lester Riquelme, Jaime Fuentealba, María Victoria Hinrichs, Juan Olate

Publikováno v: Developmental Biology. 356:131

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f752237c00ba7b7e68aa15bb8b4fb6
https://doi.org/10.1016/j.ydbio.2011.05.104