Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Gabriela Tanko"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-33 (2024)
Abstract Background Pulmonary hypertension (PH) is a complex multifactorial vascular pathology characterized by an increased pulmonary arterial pressure, vasoconstriction, remodelling of the pulmonary vasculature, thrombosis in situ and inflammation
Externí odkaz:
https://doaj.org/article/508b797fbc2a4e1db773edbda4473d46
Autor:
Miruna Nemecz, Diana Simona Stefan, Ioana Karla Comarița, Alina Constantin, Gabriela Tanko, Cristian Guja, Adriana Georgescu
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-31 (2023)
Abstract Background Circulating MicroRNAs (miRNAs) carried by microvesicles (MVs) have various physiological and pathological functions by post-transcriptional regulation of gene expression being considered markers for many diseases including diabete
Externí odkaz:
https://doaj.org/article/7d243c5e2e724bc3bb2a2ed0dec5c1da
Autor:
Laura Maria Daian, Gabriela Tanko, Andrei Mircea Vacaru, Luiza Ghila, Simona Chera, Ana-Maria Vacaru
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2023 (2023)
Diabetes is a metabolic disease that currently affects nearly half a billion people worldwide. β-cells dysfunction is one of the main causes of diabetes. Exposure to endocrine-disrupting chemicals is correlated with increased diabetes incidence. We
Externí odkaz:
https://doaj.org/article/f937838f9c7e4031aa5b517fa09cbf0e
Autor:
Geanina Voicu, Daniela Rebleanu, Cristina Ana Mocanu, Gabriela Tanko, Ionel Droc, Cristina Mariana Uritu, Mariana Pinteala, Ileana Manduteanu, Maya Simionescu, Manuela Calin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3824 (2022)
Calcific aortic valve disease (CAVD) is a progressive inflammatory disorder characterized by extracellular matrix remodeling and valvular interstitial cells (VIC) osteodifferentiation leading to valve leaflets calcification and impairment movement. R
Externí odkaz:
https://doaj.org/article/437ce64fb9ff45fabbb3622d58ba7be9
Autor:
Nicoleta Alexandru, Alina Constantin, Miruna Nemecz, Ioana Karla Comariţa, Alexandra Vîlcu, Anastasia Procopciuc, Gabriela Tanko, Adriana Georgescu
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Aim: The aim of this study was to analyze the expressed profiles of miRNAs in plasma, platelets, and platelet-derived microvesicles (PMVs) obtained from experimental induced atherosclerosis animal model and to investigate the effect of EPC transplant
Externí odkaz:
https://doaj.org/article/173591c2ec7f4dc9aba1d185795a2161
Autor:
Nicoleta Alexandru, Florentina Safciuc, Alina Constantin, Miruna Nemecz, Gabriela Tanko, Alexandru Filippi, Emanuel Dragan, Elisabeta Bãdilã, Adriana Georgescu
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The purpose was to evaluate the effect of platelets on functional properties of late endothelial progenitor cells (EPCs), in the direct co-culture conditions, and to investigate the involved mediators, in experimental induced atherosclerosis. The lat
Externí odkaz:
https://doaj.org/article/740fc36df7cb49889186c85fbb4674da
Autor:
Miruna Nemecz, Alina Constantin, Madalina Dumitrescu, Nicoleta Alexandru, Alexandru Filippi, Gabriela Tanko, Adriana Georgescu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
In this study, we aimed to identify the mechanisms underlying the different effects of palmitic acid and oleic acid on human pancreatic beta cell function. To address this problem, the oxidative stress, endoplasmic reticulum stress, inflammation, apo
Externí odkaz:
https://doaj.org/article/81da2393c32f4b46a9b20f40a2cea8d9
Autor:
Mădălina, Dumitrescu, Alina, Constantin, Andreea Miruna, Nemecz, Emanuel, Drăgan, Lucia Doina, Popov, Gabriela, Tanko
Publikováno v:
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. 62(3)
Hypertension-induced left ventricular hypertrophy evolves initially as an adaptive response meant to minimize ventricular wall stress. The mechanisms involved in the preservation of the cardiac function during the "compensatory" phase of the left ven
Autor:
Nicoleta Alexandru, Madalina Dumitrescu, Miruna Nemecz, Ariana Picu, Alina Constantin, Bogdan Smeu, Gabriela Tanko, Adriana Georgescu, Cristian Guja
Publikováno v:
Obes Surg
Pancreatic beta cells are highly sensitive to oxidative and endoplasmic reticulum (ER) stress, commonly occurring in type 2 diabetes (T2D) and obesity. We aimed at investigating cellular responses of human beta cells exposed to sera from obese T2D pa
Autor:
Florentina Safciuc, Nicoleta Alexandru, Gabriela Tanko, Miruna Nemecz, Emanuel Dragan, Alexandru Filippi, Alina Constantin, Adriana Georgescu
Publikováno v:
European Heart Journal. 40
Background MicroRNAs are involved in many processes such as cell proliferation and differentiation, angiogenesis, apoptosis, mitochondrial metabolism and DNA damage repair. Circulating levels of microRNA-210 (miR-210) are associated with the risk for