Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gabriela Seydlová"'
Autor:
Natalya Panova, Eva Zborníková, Ondřej Šimák, Radek Pohl, Milan Kolář, Kateřina Bogdanová, Renata Večeřová, Gabriela Seydlová, Radovan Fišer, Romana Hadravová, Hana Šanderová, Dragana Vítovská, Michaela Šiková, Tomáš Látal, Petra Lovecká, Ivan Barvík, Libor Krásný, Dominik Rejman
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145918 (2015)
The advantages offered by established antibiotics in the treatment of infectious diseases are endangered due to the increase in the number of antibiotic-resistant bacterial strains. This leads to a need for new antibacterial compounds. Recently, we d
Externí odkaz:
https://doaj.org/article/645b79dd6ac04f01b3677db66966ded9
Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents
Autor:
Marcel Ehn, Radek Pohl, Jiří Pospíšil, Gabriela Seydlová, Tomáš Křížek, David Sedlák, Dominik Rejman, Radovan Fišer, Libor Krásný, Oldřich Benada, Milan Kolář, Renata Večeřová, Dragana Vítovská, Petra Sudzinová, Eva Zborníková, Ondřej Šimák, Hana Šanderová, Kateřina Bogdanová, Natalya Panova, Petr Bartůněk
Publikováno v:
Journal of Medicinal Chemistry. 60:6098-6118
The increase in the number of bacterial strains resistant to known antibiotics is alarming. In this study we report the synthesis of novel compounds termed Lipophosphonoxins II (LPPO II). We show that LPPO II display excellent activities against Gram
Autor:
Radomír Čabala, Gabriela Seydlová, Róbert Kubinec, Peter Kotora, Václav Matěj Bierhanzl, Viktória Ferenczy, Jaroslav Blaško, Martin Ston
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 147:1385-1391
Direct injection mass spectrometry was amended with chromatographic methods in analysis of membrane phospholipids of Bacillus subtilis mutant strain, which contains four polar headgroups only (phosphatidylglycerol, phosphatidylethanolamine, phosphati
Publikováno v:
Antimicrobial agents and chemotherapy. 63(1)
Daptomycin is a calcium-dependent lipodepsipeptide antibiotic clinically used to treat serious infections caused by Gram-positive pathogens. Its precise mode of action is somewhat controversial; the biggest issue is daptomycin pore formation, which w
Autor:
Radovan Fišer, Ivo Konopásek, Jana Beranová, Branislav Večerek, Jakub Drzmisek, Gabriela Seydlová, Jiri Masin, Ilona Bibova, Ana Dienstbier
Changes in environmental temperature represent one of the major stresses faced by microorganisms as they affect the function of the cytoplasmic membrane. In this study, we have analyzed the thermal adaptation in two closely related respiratory pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043833602718f761d1bbb1fdd29be6d5
https://europepmc.org/articles/PMC5427280/
https://europepmc.org/articles/PMC5427280/
Publikováno v:
Neuromethods ISBN: 9781493969449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089687b4453738a52f3cb3bc4878c90a
https://doi.org/10.1007/978-1-4939-6946-3_11
https://doi.org/10.1007/978-1-4939-6946-3_11
Autor:
Jaroslava Svobodová, Olga Bechyňková, Dominik Pinkas, Radovan Fišer, Petra Uttlová, Gabriela Seydlová
Publikováno v:
Biochimica et biophysica acta. 1858(12)
Surfactin, an anionic lipopeptide produced by Bacillus subtilis, is an antimicrobial that targets the cytoplasmic membrane. Nowadays it appears increasingly apparent that the mechanism of resistance against these types of antibiotics consists of targ
Autor:
Gabriela Seydlová, Ivo Konopásek, Halyna Kozak, Alexander Kromka, Štěpán Potocký, Jana Beranová
Publikováno v:
physica status solidi (b). 249:2581-2584
In this study, we investigated the potential antibacterial properties of nanocrystalline diamond. In particular, we tested the effect of diamond nanoparticles (DNPs) on growth of the model gram-negative bacterium Escherichia coli on solid, nutrient-r
Publikováno v:
Journal of Applied Microbiology. 112:765-774
Aims: To find out membrane tolerance strategy to ethanol in Bacillus subtilis that possesses a powerful system of protection against environmental stresses. Methods and Results: Cytoplasmic membranes of B. subtilis were severely affected by even shor
Autor:
Jaroslava Svobodová, Gabriela Seydlová
Publikováno v:
Folia Microbiologica. 53:303-307
Processes occurring in the cytoplasmic membrane of the surfactin producer Bacillus subtilis were examined during a 3-d cultivation. The fatty acid composition was found to be almost stable within this interval, except for the early stationary phase w