Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gabriela S. Alvarado"'
Autor:
Lauren A. Ford-Siltz, Kentaro Tohma, Gabriela S. Alvarado, Joseph A. Kendra, Kelsey A. Pilewski, James E. Crowe, Gabriel I. Parra
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human noroviruses are the major viral cause of acute gastroenteritis around the world. Although norovirus symptoms are in most cases mild and self-limited, severe and prolonged symptoms can occur in the elderly and in immunocompromised individuals. T
Externí odkaz:
https://doaj.org/article/4a75487ab0e4486284fccc0de72053b2
Autor:
Kai Wu, Ian N. Moore, Bridget Bart, John-Paul Todd, Elham Bayat Mokhtari, Gabriela S. Alvarado, Swagata Kar, Jaclyn Wear, Manjari Sriparna, Kathryn E. Foulds, Matthew Gagne, Mario Roederer, Kizzmekia S. Corbett, Seyhan Boyoglu-Barnum, Darin K. Edwards, Barbara J. Flynn, Katelyn Steingrebe, Adrian B. McDermott, Samantha J. Provost, Angela Choi, Shayne F. Andrew, Eli Boritz, Sayda Elbashir, Zackery Flinchbaugh, Timothy S. Johnston, Martha Nason, Sarah O’ Connell, Anthony Cook, Bianca M. Nagata, Mahnaz Minai, Prakriti Mudvari, Mark G. Lewis, Andrew Pekosz, Amy R. Henry, Farida Laboune, Dillon R. Flebbe, Becky Chang, Alex Van Ry, Nancy J. Sullivan, Juan I. Moliva, Saule T. Nurmukhambetova, Laurent Pessaint, Lilin Lai, Matthew A. Koch, Barney S. Graham, Hanne Leth Andersen, Maciel Porto, Kevin W. Bock, Daniel C. Douek, Anne P. Werner, Mehul S. Suthar, Evan Lamb, Alan Dodson, Andrea Carfi, Robert A. Seder
Publikováno v:
Nature Immunology. 22:1306-1315
B.1.351 is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant most resistant to antibody neutralization. We demonstrate how the dose and number of immunizations influence protection. Nonhuman primates received two doses of 30 or
Autor:
Ian N. Moore, Seyhan Boyoglu-Barnum, Swagata Kar, Bianca M. Nagata, Shayne F. Andrew, Joseph R. Francica, John R. Mascola, Shruti N. Shah, Darin K. Edwards, Samantha J. Provost, Barney S. Graham, John Paul Todd, Venkata Viswanadh Edara, Eun Sung Yang, Daniel Valentin, Katelyn Steingrebe, David C. Montefiori, Andrea Carfi, Maciel Porto, Hanne Leth Andersen, Robert A. Seder, Kizzmekia S. Corbett, Wei Shi, Jack Greenhouse, Mark G. Lewis, Evan Lamb, Adrian B. McDermott, Daniel C. Douek, Serge Zouantcha, Kathryn E. Foulds, Nancy J. Sullivan, Mahnaz Minai, Kevin W. Bock, Britta Flach, Lilin Lai, Katharine Floyd, Angela Choi, Charlene McDanal, Jonathan Fintzi, Alan Dodson, Matthew A. Koch, Mario Roederer, Amy T. Noe, Juan I. Moliva, Saule T. Nurmukhambetova, Mitzi M. Donaldson, Laurent Pessaint, Timothy S. Johnston, Andrew Faudree, Anne P. Werner, Mehul S. Suthar, Barbara J. Flynn, Kai Wu, Anthony L. Cook, Sarah O’Connell, Gabriela S. Alvarado, Lingshu Wang, Yi Zhang, Martha Nason, Dillon R. Flebbe, Matthew Gagne, Olubukola M. Abiona, Renee van de Wetering, Kwanyee Leung
Publikováno v:
Science
Immune correlates of protection can be used as surrogate endpoints for vaccine efficacy. The nonhuman primate (NHP) model of SARS-CoV-2 infection replicates key features of human infection and may be used to define immune correlates of protection fol
Autor:
Daniel C. Douek, Rachel L. Davis, Alex Van Ry, Timothy S. Johnston, Stephen D. Schmidt, Adrian B. McDermott, John R. Mascola, Yi Zhang, Anne P. Werner, Lilin Lai, Evan Lamb, Sarah O’ Connell, Kevin W. Bock, John-Paul Todd, Misook Choe, Amy R. Henry, Wei Shi, Alan Dodson, Danielle A. Wagner, Matthew A. Koch, Barney S. Graham, Aurélie Ploquin, Mehul S. Suthar, Farida Laboune, Chaim A. Schramm, Mitzi M. Donaldson, Samantha J. Provost, John Misasi, Christopher Stringham, Bianca M. Nagata, Hanne Leth Andersen, Ian N. Moore, Kizzmekia S. Corbett, Andrea Carfi, Robert A. Seder, Sandeep Narpala, Seyhan Boyoglu-Barnum, Mark G. Lewis, Josue Marquez, Sijy O'Dell, Nancy J. Sullivan, Lingshu Wang, Juan I. Moliva, Saule T. Nurmukhambetova, Courtney Tucker, Zackery Flinchbaugh, Laurent Pessaint, Shayne F. Andrew, Mahnaz Minai, Eli Boritz, Barbara J. Flynn, Andrew Pekosz, Dillon R. Flebbe, Daniel Valentin, Darin K. Edwards, Matthew Gagne, Angela Choi, Manjari Sriparna, Kathryn E. Foulds, Martha Nason, Anthony L. Cook, Gabriela S. Alvarado, Kai Wu, Nicole A. Doria-Rose, Mario Roederer
Publikováno v:
bioRxiv
Neutralizing antibody responses gradually wane after vaccination with mRNA-1273 against several variants of concern (VOC), and additional boost vaccinations may be required to sustain immunity and protection. Here, we evaluated the immune responses i
Autor:
Andrea Carfi, John R. Mascola, Nancy J. Sullivan, Barney S. Graham, Kizzmekia S. Corbett, Mahnaz Minai, Olubukola M. Abiona, Tracy J. Ruckwardt, Anne P. Werner, Gabriela S. Alvarado, Ralph S. Baric, Anthony T. DiPiazza, Ian N. Moore, Lauren A. Chang, Darin K. Edwards, Emily Phung, Juan I. Moliva, Sarah R. Leist, Kenneth H. Dinnon, Seyhan Boyoglu-Barnum, Bianca M. Nagata, Rebecca J. Loomis, Kaitlyn M. Morabito, Alexandra Schäfer, Kevin W. Bock
Publikováno v:
Immunity
Vaccine-associated enhanced respiratory disease (VAERD) was previously observed in some preclinical models of severe acute respiratory syndrome (SARS) and MERS coronavirus vaccines. We used the SARS coronavirus 2 (SARS-CoV-2) mouse-adapted, passage 1
Autor:
Kizzmekia S. Corbett, Anne P. Werner, Sarah O’ Connell, Matthew Gagne, Lilin Lai, Juan I. Moliva, Barbara Flynn, Angela Choi, Matthew Koch, Kathryn E. Foulds, Shayne F. Andrew, Dillon R. Flebbe, Evan Lamb, Saule T. Nurmukhambetova, Samantha J. Provost, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Alex Van Ry, Zackery Flinchbaugh, Timothy S. Johnston, Elham Bayat Mokhtari, Prakriti Mudvari, Amy R. Henry, Farida Laboune, Becky Chang, Maciel Porto, Jaclyn Wear, Gabriela S. Alvarado, Seyhan Boyoglu-Barnum, John-Paul M. Todd, Bridget Bart, Anthony Cook, Alan Dodson, Laurent Pessaint, Katelyn Steingrebe, Sayda Elbashir, Hanne Andersen, Kai Wu, Darin K. Edwards, Swagata Kar, Mark G. Lewis, Eli Bortiz, Ian N. Moore, Andrea Carfi, Mehul S. Suthar, Adrian McDermott, Mario Roederer, Martha C. Nason, Nancy J. Sullivan, Daniel C. Douek, Barney S. Graham, Robert A. Seder
Publikováno v:
bioRxiv
BackgroundVaccine efficacy against the B.1.351 variant following mRNA-1273 vaccination in humans has not been determined. Nonhuman primates (NHP) are a useful model for demonstrating whether mRNA-1273 mediates protection against B.1.351.MethodsNonhum
Autor:
Kizzmekia S. Corbett, Martha C. Nason, Britta Flach, Matthew Gagne, Sarah O’ Connell, Timothy S. Johnston, Shruti N. Shah, Venkata Viswanadh Edara, Katharine Floyd, Lilin Lai, Charlene McDanal, Joseph R. Francica, Barbara Flynn, Kai Wu, Angela Choi, Matthew Koch, Olubukola M. Abiona, Anne P. Werner, Gabriela S. Alvarado, Shayne F. Andrew, Mitzi M. Donaldson, Jonathan Fintzi, Dillon R. Flebbe, Evan Lamb, Amy T. Noe, Saule T. Nurmukhambetova, Samantha J. Provost, Anthony Cook, Alan Dodson, Andrew Faudree, Jack Greenhouse, Swagata Kar, Laurent Pessaint, Maciel Porto, Katelyn Steingrebe, Daniel Valentin, Serge Zouantcha, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Juan I. Moliva, Renee van de Wetering, Seyhan Boyoglu-Barnum, Kwanyee Leung, Wei Shi, Eun Sung Yang, Yi Zhang, John-Paul M. Todd, Lingshu Wang, Hanne Andersen, Kathryn E. Foulds, Darin K. Edwards, John R. Mascola, Ian N. Moore, Mark G. Lewis, Andrea Carfi, David Montefiori, Mehul S. Suthar, Adrian McDermott, Nancy J. Sullivan, Mario Roederer, Daniel C. Douek, Barney S. Graham, Robert A. Seder
Publikováno v:
bioRxiv
Immune correlates of protection can be used as surrogate endpoints for vaccine efficacy. The nonhuman primate (NHP) model of SARS-CoV-2 infection replicates key features of human infection and may be used to define immune correlates of protection fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a2c90ec45ef1373e88339143a1b79f
https://doi.org/10.1101/2021.04.20.440647
https://doi.org/10.1101/2021.04.20.440647
Autor:
Eun Sung Yang, Cuiping Liu, Nicole A. Doria-Rose, Dario Garcia-Dominguez, Hamilton Bennett, Nianshuang Wang, Kapil Bahl, Nedim Emil Altaras, Kaitlyn M. Morabito, Alexandra Schäfer, Kevin W. Bock, John R. Mascola, Kai Wu, Guillaume Stewart-Jones, Ethan J. Fritch, Kizzmekia S. Corbett, Kwanyee Leung, Mahnaz Minai, Ling Zhi Ma, Andrea Carfi, Christine A. Shaw, Barney S. Graham, Mark K. Louder, Anthony T. DiPiazza, Wing Pui Kong, Stephen D. Schmidt, Yi Zhang, Sayda Elbashir, Ande West, Gabriela S. Alvarado, Wei Shi, Isabella Renzi, Ralph S. Baric, Elisabeth Narayanan, Mihir Metkar, Bianca M. Nagata, Tracy J. Ruckwardt, Rebecca J. Loomis, Martha Nason, Darin K. Edwards, Cynthia T. Ziwawo, Sunny Himansu, Emily Phung, Seyhan Boyoglu-Barnum, Laura J. Stevens, Kendra Gully, Carole Henry, Olubukola M. Abiona, Angela Woods, Lauren A. Chang, Sarah R. Leist, Geoffrey B. Hutchinson, Daniel Wrapp, Kenneth H. Dinnon, James D. Chappell, Lingshu Wang, Vlad Presnyak, Rebecca A. Gillespie, Jason S. McLellan, David R. Martinez, Ian N. Moore, Mark R. Denison
Publikováno v:
Nature
A vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is needed to control the coronavirus disease 2019 (COVID-19) global pandemic. Structural studies have led to the development of mutations that stabilize Betacoronavirus spike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb9dfcf84b0b1edbdebf8300c5160b8
Autor:
Ingelise J. Gordon, Mark G. Lewis, Gabriela S. Alvarado, Ralph S. Baric, Martin R. Gaudinski, Laura Novik, Kwanyee Leung, Jack Greenhouse, Tammy Putman-Taylor, Katelyn Steingrebe, Seyhan Boyoglu-Barnum, Kathryn E. Foulds, Tracey-Ann Campbell, Tongqing Zhou, Wei Shi, I-Ting Teng, Peter D. Kwong, Juan I. Moliva, Laurent Pessaint, Christina Yap, Mahnaz Minai, Olubukola M. Abiona, Nancy J. Sullivan, Nadesh N Nji, Kaitlyn M. Morabito, Amarendra Pegu, Stephen D. Schmidt, Julie E. Ledgerwood, Sunny Himansu, Barbara J. Flynn, Shanai Browne, Anne P. Werner, Darin K. Edwards, Eun Sung Yang, Kevin W. Bock, Joseph R. Francica, Yi Zhang, Dillon R. Flebbe, Kizzmekia S. Corbett, Nicole A. Doria-Rose, Ian N. Moore, Andrea Carfi, Amanda Strasbaugh, Mario Roederer, Guillaume Stewart-Jones, Emily Phung, Robert A. Seder, Tracy J. Ruckwardt, Adrian B. McDermott, Anthony Cook, Sarah O’Connell, Alicia T. Widge, Wing-Pui Kong, Mark K. Louder, Martha Nason, Bob C. Lin, David R. Martinez, Alex Van Ry, Alan Dodson, Evan Lamb, Britta Flach, Bianca M. Nagata, Rebecca J. Loomis, John R. Mascola, Barney S. Graham, John-Paul Todd, Sijy O'Dell, Lauren A. Chang, Naomi Douek, Lingshu Wang, Rebecca A. Gillespie, Hanne Leth Andersen, Amy T. Noe, Mitzi M. Donaldson
Publikováno v:
New England Journal of Medicine
The New England Journal of Medicine
The New England Journal of Medicine
Background: Vaccines to prevent coronavirus disease 2019 (Covid-19) are urgently needed. The effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines on viral replication in both upper and lower airways is important to evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1beae7dcc7af2b55333337512c240b