Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis

Autor: Letycia Silvano da Silva, Tatiana Tocchini Felippotti, Maria José Alves da Rocha, Carlos Henrique Rocha Catalão, Luís Alexandre Pedro de Freitas, Gabriela Ravanelli Oliveira-Pelegrin, S. O. Petenusci

Publikováno v: Pharmaceutical Biology, Vol 55, Iss 1, Pp 269-276 (2017)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Context: Curcumin has been reported to have anti-inflammatory, antioxidant and hypoglycaemic properties, besides reducing mortality in sepsis. Objective: This study evaluates the biological activities of a curcumin dispersion formulated by spray-dryi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3caa656d6457e700e87f98eccae282d2
https://doaj.org/article/8a3a87e0b027424f956b92934492d66a

Contents Vol. 24, 2015

Autor: Maria do Carmo Tomitão Canas, Yuan-Ti Lee, Yasar Zorlu, Dorota Pojda-Wilczek, Petru Adrian Mircea, Uğur Arslan, Chun-Chieh Chen, İsmail Gökhan Çavuşoğlu, Adriana Renzi, C.I. Ezeamuzie, Ralf Schneider, Tatjana Gazibara, Olga Nurieva, Ali Dogan, Mustafa Tarık Ağaç, Anna Piotrowska-Gwozdz, Marius Andronache, İhsan Dursun, Mehmet Agilli, Ozgur Oztekin, Ahmet Seyda Yılmaz, Adriana M. Nascimento, Grazyna Ginalska, Dana Pop, Sanja Radovanovic, Gökhan Aksan, Tatjana Pekmezovic, Huei-Chao Lee, Orhan Kursat Poyrazoglu, Mustafa Mücahit Balcı, Mustafa Aparci, Ana L. Mauri, Elwira Sieniawska, Alexander Novotny, Biljana Rancic, Burcu Selbest Demirtaş, Şükrü Çelik, Laura D. Vagnini, Joao Batista A. Oliveira, Ibrahim Halil Bahcecioglu, Meng-Chih Lee, Metin Murat Özçelik, Adrian Smedowski, Gülhanım Kırış, Lucian Muresan, Paul Puie, Gabriel Cismaru, Chin-Feng Tsai, Karolina Mikus-Zagorska, Werner Druck Medien Ag, Gizem Çelik, M.A. Oriowo, Cengiz Ozturk, Nihal El Kamar, Ayşe Diljin Keçeci, Buglem Ureyen Kaya, Levent Ocek, Gabriel Gusetu, Zekeriya Arslan, Dumitru Zdrenghea, Sait Demirkol, Ahmet Oguz Aslan, Radu Rosu, Gorica Maric, Marta Swatko-Ossor, Tuncer Cayci, Sinan Aydoğdu, Ercan Kocakoc, Mario Cavagna, Dietrich Doll, Rafal Sawicki, Sevket Balta, Jose G. Franco, Mihai Puiu, İbrahim Kocaoğlu, Haydar Sipahioğlu, Yavuzer Koza, Gabriela Ravanelli Oliveira-Pelegrin, Roxana Matuz, Ayse Ahsen Bakan, Dilek Cahide Kırcı, Adile Ferda Dagli, Yeliz Gul, Po-Jen Yang, Agnieszka Jakubowska, Claudia G. Petersen, Patrycja Orchel, Shiuan-Chih Chen, S.N. El-Zohairy, Markus M. Luedi, Necdet Adanir, Korhan Soylu, Satz Mengensatzproduktion, Shu-Ling Tzeng, Yasemin Gulcan Kurt, Sinan İnci, Mehtap Cicekci, Agnieszka Piotrowska-Seweryn, Levent Korkmaz, Ufuk Şener, Hakan Erkan, Gökay Nar, Dominic van der Zypen, Ricardo L. R. Baruffi, Katerina Kotikova, Edouard Matevossian, Fevzi Nuri Aydin, Darija Kisic-Tepavcevic

Publikováno v: Medical Principles and Practice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf95d49de29640b4f6f44df728d9240
http://europepmc.org/articles/PMC5588286

Endogenous peripheral hydrogen sulfide is propyretic: its permissive role in brown adipose tissue thermogenesis in rats

Autor: Gabriela Ravanelli Oliveira-Pelegrin, Luiz G.S. Branco, Sara Pereira Braga, Marcelo E. Batalhão, Maria José Alves da Rocha, Jéssica S. C. Breder, Renato N. Soriano, Evelin Capellari Cárnio, Luiz Fernando Romanholo Ferreira

Publikováno v: Experimental physiology. 103(3)

NEW FINDINGS What is the central question of this study? In fever, the most striking response in the acute phase reaction of systemic inflammation, plasma H2 S concentration increases. However, the role of endogenous peripheral H2 S in fever is unkno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08af7cc649327a14f37dee43c544c297
https://pubmed.ncbi.nlm.nih.gov/29210120

Inhibition of neuronal nitric oxide synthase activity does not alter vasopressin secretion in septic rats

Autor: Maria José Alves da Rocha, Gabriela Ravanelli Oliveira-Pelegrin, Camila H. Coelho, Thalita Freitas Martins

Publikováno v: Pituitary. 20(3)

During the early phase of sepsis, hypotension is accompanied by increase of plasma vasopressin hormone (AVP) levels, which decline during the late phase. This hypotension is due in part to increase of nitric oxide (NO) synthesis by nitric oxide synth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a2a18b9c3819174e2c81175868503f
https://pubmed.ncbi.nlm.nih.gov/28091880

Role of central NO-cGMP pathway in vasopressin and oxytocin gene expression during sepsis

Autor: Gabriela Ravanelli Oliveira-Pelegrin, Paulo José Basso, Maria José Alves da Rocha, Fábio Alves Aguila

Publikováno v: Peptides. 31:1847-1852

Sepsis induces massive production of inflammatory mediators, such as nitric oxide (NO), and causes neuroendocrine and cardiovascular alterations. This study investigates the involvement of the central NO-cGMP pathway in arginine vasopressin (AVP) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9476e6f24dcbef3951b052a818cd27
https://doi.org/10.1016/j.peptides.2010.06.031