Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gabriela R Moura"'
Autor:
Rui Marçalo, Sonya Neto, Miguel Pinheiro, Ana J Rodrigues, Nuno Sousa, Manuel A S Santos, Paula Simão, Carla Valente, Lília Andrade, Alda Marques, Gabriela R Moura
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264009 (2022)
BackgroundPopulations seem to respond differently to the global pandemic of severe acute respiratory syndrome coronavirus 2. Recent studies show individual variability in both susceptibility and clinical response to COVID-19 infection. People with ch
Externí odkaz:
https://doaj.org/article/76f7304af13d4cb3b38edef8db0cef6a
Autor:
Sonya Neto, Andreia Reis, Miguel Pinheiro, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Santos, Ana João Rodrigues, Nuno Sousa, Manuel A. S. Santos, Gabriela R. Moura
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Background Aging represents a significant risk factor for the occurrence of cerebral small vessel disease, associated with white matter (WM) lesions, and to age-related cognitive alterations, though the precise mechanisms remain largely unkn
Externí odkaz:
https://doaj.org/article/2e0c7763ac12478f9c1753c74e574d65
Autor:
Marta Cela, Caroline Paulus, Manuel A S Santos, Gabriela R Moura, Magali Frugier, Joëlle Rudinger-Thirion
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209805 (2018)
The life cycle of Plasmodium falciparum, the agent responsible for malaria, depends on both cytosolic and apicoplast translation fidelity. Apicoplast aminoacyl-tRNA synthetases (aaRS) are bacterial-like enzymes devoted to organellar tRNA aminoacylati
Externí odkaz:
https://doaj.org/article/e14951447aab4e6da6d95cfadfba7229
Autor:
Gabriela R Moura, Miguel Pinheiro, Adelaide Freitas, José L Oliveira, Jörg C Frommlet, Laura Carreto, Ana R Soares, Ana R Bezerra, Manuel A S Santos
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145593 (2015)
Externí odkaz:
https://doaj.org/article/6fa0225e6a6f47e189e1438db1333b1f
Autor:
Ana R Soares, Marisa Reverendo, Patrícia M Pereira, Olivier Nivelles, Hélène Pendeville, Ana Rita Bezerra, Gabriela R Moura, Ingrid Struman, Manuel A S Santos
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39417 (2012)
BACKGROUND: MicroRNAs (miRNAs) are a class of small RNAs that are implicated in the control of eukaryotic gene expression by binding to the 3'UTR of target mRNAs. Several algorithms have been developed for miRNA target prediction however, experimenta
Externí odkaz:
https://doaj.org/article/5c5288d7db21424c96e4b44e1d9772b9
Autor:
Gabriela R Moura, Miguel Pinheiro, Adelaide Freitas, José L Oliveira, Jörg C Frommlet, Laura Carreto, Ana R Soares, Ana R Bezerra, Manuel A S Santos
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26817 (2011)
Codon pair usage (codon context) is a species specific gene primary structure feature whose evolutionary and functional roles are poorly understood. The data available show that codon-context has direct impact on both translation accuracy and efficie
Externí odkaz:
https://doaj.org/article/bcb69cd0ed29424e81502889e6223b70
Autor:
Raquel M Silva, Iven C N Duarte, João A Paredes, Tatiana Lima-Costa, Michel Perrot, Hélian Boucherie, Brian J Goodfellow, Ana C Gomes, Denisa D Mateus, Gabriela R Moura, Manuel A S Santos
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5212 (2009)
Translation fidelity is critical for protein synthesis and to ensure correct cell functioning. Mutations in the protein synthesis machinery or environmental factors that increase synthesis of mistranslated proteins result in cell death and degenerati
Externí odkaz:
https://doaj.org/article/943e46601d564f488bffc94f1ed080f8
A genetic code alteration is a phenotype diversity generator in the human pathogen Candida albicans.
Autor:
Isabel Miranda, Rita Rocha, Maria C Santos, Denisa D Mateus, Gabriela R Moura, Laura Carreto, Manuel A S Santos
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e996 (2007)
BACKGROUND: The discovery of genetic code alterations and expansions in both prokaryotes and eukaryotes abolished the hypothesis of a frozen and universal genetic code and exposed unanticipated flexibility in codon and amino acid assignments. It is n
Externí odkaz:
https://doaj.org/article/411fccf8421b484c9e2697f4f4b3301a
Autor:
Rui Marçalo, Sonya Neto, Miguel Pinheiro, Ana J. Rodrigues, Nuno Sousa, Manuel A. S. Santos, Paula Simão, Carla Valente, Lília Andrade, Alda Marques, Gabriela R. Moura
Publikováno v:
PloS one. 17(2)
Background Populations seem to respond differently to the global pandemic of severe acute respiratory syndrome coronavirus 2. Recent studies show individual variability in both susceptibility and clinical response to COVID-19 infection. People with c
Autor:
Tobias Weil, Rodrigo Santamaría, Wanseon Lee, Johan Rung, Noemi Tocci, Darren Abbey, Ana R. Bezerra, Laura Carreto, Gabriela R. Moura, Mónica Bayés, Ivo G. Gut, Attila Csikasz-Nagy, Duccio Cavalieri, Judith Berman, Manuel A. S. Santos
Publikováno v:
mSphere, Vol 2, Iss 4 (2017)
ABSTRACT Regulated erroneous protein translation (adaptive mistranslation) increases proteome diversity and produces advantageous phenotypic variability in the human pathogen Candida albicans. It also increases fitness in the presence of fluconazole,
Externí odkaz:
https://doaj.org/article/27634fd55d184dabb3cf213225caa91a