Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gabriela Pirgova"'
Autor:
Julie M. Mazet, Jagdish N. Mahale, Orion Tong, Robert A. Watson, Ana Victoria Lechuga‐Vieco, Gabriela Pirgova, Vivian W. C. Lau, Moustafa Attar, Lada A. Koneva, Stephen N. Sansom, Benjamin P. Fairfax, Audrey Gérard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
IFN-γ is associated with the efficacy of anti-tumour immune responses, and both pro- and anti-tumour functions have been ascribed to this cytokine. Here, the authors demonstrate that IFN-γ signalling inhibits the maintenance of stem-like T cells, t
Externí odkaz:
https://doaj.org/article/87336a705ef745dd8cce2ca5689d01e8
Autor:
Kristina Zec, Barbora Schonfeldova, Zhichao Ai, Erinke Van Grinsven, Gabriela Pirgova, Hayley L. Eames, Dorothée L. Berthold, Moustafa Attar, Ewoud B. Compeer, Tal I. Arnon, Irina A. Udalova
Publikováno v:
Journal of Experimental Medicine. 220
The first immune-activating changes within joint resident cells that lead to pathogenic leukocyte recruitment during articular inflammation remain largely unknown. In this study, we employ state-of-the-art confocal microscopy and image analysis in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e5366102a10b9952e9db59288cb3feb
https://doi.org/10.1084/jem.20220595
https://doi.org/10.1084/jem.20220595
Autor:
Tariq E. Khoyratty, Bin Xie, Gabriela Pirgova, Tal I. Arnon, Enas Abu-Shah, Andrew J. MacLean, Michael L. Dustin, Zhiyuan Hu, Pablo F. Céspedes, Ahmed Ashour Ahmed, Irina A. Udalova
Publikováno v:
The Journal of Immunology Author Choice
Key Points The Zinc finger protein, Zbtb18, is downregulated during PC differentiation. Enhanced expression of Zbtb18 leads to impaired PC development. Zbtb18 directly binds and inhibits expression of PI3K subunits.
The PI3K pathway plays a key
The PI3K pathway plays a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15f4dd6b4c53c20f0ff51c27e9c0138
http://europepmc.org/articles/PMC7980533
http://europepmc.org/articles/PMC7980533
Publikováno v:
Proceedings of the National Academy of Sciences. 117:12295-12305
The mechanisms that regulate germinal center (GC) B cell responses in the spleen are not fully understood. Here we use a combination of pharmacologic and genetic approaches to delete SIGN-R1+ marginal zone (MZ) macrophages and reveal their specific c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb01ab5ea28d91d121b35a215d3147b2
https://doi.org/10.1073/pnas.1921673117
https://doi.org/10.1073/pnas.1921673117
Autor:
Anne Chauveau, Gabriela Pirgova, Jens Rittscher, Tal I. Arnon, Burkhard Ludewig, Felix Zhou, S Wideman, Cheng H-W., A De Martin
Publikováno v:
Cellular and Molecular Immunology
Summary Lymphocyte homeostasis and immune surveillance require that T and B cells continuously recirculate between secondary lymphoid organs. Here, we used intravital microscopy to define lymphocyte trafficking routes within the spleen, an environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e26099277001f185ad84c1cc194d774
https://ora.ox.ac.uk/objects/uuid:66dfd5f2-06b1-45f8-8a61-71be08c4853e
https://ora.ox.ac.uk/objects/uuid:66dfd5f2-06b1-45f8-8a61-71be08c4853e
