Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gabriela Pacheco-Sanchez"'
Autor:
Adam-Nicolas Pelletier, Gabriela Pacheco Sanchez, Abdullah Izmirly, Mark Watson, Tiziana Di Pucchio, Karina Inacio Carvalho, Abdelali Filali-Mouhim, Eustache Paramithiotis, Maria do Carmo S.T. Timenetsky, Alexander Roberto Precioso, Jorge Kalil, Michael S. Diamond, Elias K. Haddad, Esper G. Kallas, Rafick Pierre Sekaly
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114370- (2024)
Summary: Protective immunity to dengue virus (DENV) requires antibody response to all four serotypes. Systems vaccinology identifies a multi-OMICs pre-vaccination signature and mechanisms predictive of broad antibody responses after immunization with
Externí odkaz:
https://doaj.org/article/c2f9d70be3a14ae48b795b2d938c7d44
Autor:
Michael Maschan, Paolo F. Caimi, Jane Reese-Koc, Gabriela Pacheco Sanchez, Ashish A. Sharma, Olga Molostova, Larisa Shelikhova, Dmitriy Pershin, Alexey Stepanov, Yakov Muzalevskii, Vinicius G. Suzart, Folashade Otegbeye, David Wald, Ying Xiong, Darong Wu, Adam Knight, Ibe Oparaocha, Beatrix Ferencz, Andre Roy, Andrew Worden, Winfried Kruger, Michael Kadan, Dina Schneider, Rimas Orentas, Rafick-Pierre Sekaly, Marcos de Lima, Boro Dropulić
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Strategies to address the challenges associated with product manufacturing can improve chimeric antigen receptor (CAR) cell–based therapeutics. Here the authors report the results of two clinical trials in patients with B-cell malignancies, showing
Externí odkaz:
https://doaj.org/article/1879f85252424882a5288bc97bee3406
Autor:
Brian Ferrari, Amanda Cabral Da Silva, Ken H. Liu, Evgeniya V. Saidakova, Larisa B. Korolevskaya, Konstantin V. Shmagel, Carey Shive, Gabriela Pacheco Sanchez, Mauricio Retuerto, Ashish Arunkumar Sharma, Khader Ghneim, Laura Noel-Romas, Benigno Rodriguez, Mahmoud A. Ghannoum, Peter P. Hunt, Steven G. Deeks, Adam D. Burgener, Dean P. Jones, Mirela A. Dobre, Vincent C. Marconi, Rafick-Pierre Sekaly, Souheil-Antoine Younes
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
People living with HIV (PLWH) who are immune nonresponders (INRs) are at greater risk of comorbidity and mortality than are immune responders (IRs) who restore their CD4+ T cell count after antiretroviral therapy (ART). INRs have low CD4+ T cell coun
Externí odkaz:
https://doaj.org/article/2e7dbc6137fc40d5aa924fb147bf5c0a
Autor:
Paolo F. Caimi, Gabriela Pacheco Sanchez, Ashish Sharma, Folashade Otegbeye, Nausheen Ahmed, Patricio Rojas, Seema Patel, Sarah Kleinsorge Block, Jennifer Schiavone, Kayla Zamborsky, Kirsten Boughan, Antoinette Hillian, Jane Reese-Koc, Mikhail Maschan, Boro Dropulic, Rafick-Pierre Sekaly, Marcos de Lima
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Anti-CD19 chimeric antigen receptor T (CAR-T) cells have demonstrated activity against relapsed/refractory lymphomas. Cytokine release syndrome (CRS) and immune effector cell – associated neurotoxicity syndrome (ICANS) are well-known complications.
Externí odkaz:
https://doaj.org/article/b8b7b782c28b4871b38e4eeaec8b2a0f
Autor:
Rachel Pope, Muhammad Bilal Latif, Gabriela Pacheco Sanchez, Meredith Elizabeth Davis Gardner, Ruth Farrell, Kelly Gibson, Meng Yao, Sarah O'connell, Supra Gajjaia, Adrian McDermont, Ellen Divoky, Ellie Ragsdale, Robert Balderas, Michael Konstan, Mehul Suthar, Rafick-Pierre Sekaly, Susan Pereira Ribeiro
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9770cf408f0e5d8e4c00fa0d1ae8cc3
https://doi.org/10.2139/ssrn.4118565
https://doi.org/10.2139/ssrn.4118565
Autor:
Adam Nicolas Pelletier, Gabriela Pacheco Sanchez, Abdullah Izmirly, Mark Watson, Tiziana Di Pucchio, Karina Inacio Carvalho, Abdelali Filali-Mouhim, Eustache Paramithiotis, Jorge Kalil, Maria do Carmo S. T. Timenetsky, Alexander Roberto Precioso, Michael S. Diamond, Elias K. Haddad, Esper Georges Kallas, Rafick-Pierre Sekaly
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03eb45b69b6e8e606b287f04af7eac26
https://doi.org/10.2139/ssrn.4113517
https://doi.org/10.2139/ssrn.4113517
Autor:
Nausheen Ahmed, Marcos de Lima, Sarah Kleinsorge Block, Folashade Otegbeye, Patricio Rojas, Jane Reese-Koc, Seema Patel, Boro Dropulic, Ashish Sharma, Kirsten M Boughan, Jennifer Schiavone, Paolo Caimi, Gabriela Pacheco Sanchez, Antoinette Hillian, M.A. Maschan, Rafick-Pierre Sekaly, Kayla Zamborsky
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Anti-CD19 chimeric antigen receptor T (CAR-T) cells have demonstrated activity against relapsed/refractory lymphomas. Cytokine release syndrome (CRS) and immune effector cell – associated neurotoxicity syndrome (ICANS) are well-known complications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647f1575b2c38ac5866b33b74201e962
https://www.frontiersin.org/articles/10.3389/fimmu.2021.745320/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.745320/full
Autor:
Mark Watson, Adam Pelletier, Elias K. Haddad, Michael P. Diamond, Abdullah M Izmirly, Esper G. Kallas, Gabriela Pacheco Sanchez, Eustache Paramithiotis, Rafick Pierre Sekaly, Jorge Khalil, Tiziana Di Pucchio
Development of fully protective dengue virus (DV) vaccines has been problematic as infection with DV requires a broad antibody immune response that targets all 4 possible serotypes. Herein, we used an integrated systems vaccinology approach to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b47ce1d902fcbbd60045220dcf26f1bd
https://doi.org/10.1101/2021.09.25.21264123
https://doi.org/10.1101/2021.09.25.21264123
Autor:
Guido Ferrari, Neeta Shenvi, Thomas H. Vanderford, Susan Pereira Ribeiro, Wen-Hsiang Chen, David C. Montefiori, Talha Abid, Alessandro Sette, Daniela Weiskopf, Debashis Dutta, Katharine Floyd, Shelly Wang, Dieter Mielke, Sudhir Pai Kasturi, Georgia D. Tomaras, Pamela A. Kozlowski, Celia C. LaBranche, Maria Pino, Jungsoon Lee, Sherrie Jean, Venkata Viswanadh Edara, Xiaoying Shen, Justin Pollara, Justin C Smith, Mirko Paiardini, Rafick Pierre Sekaly, Fawn Connor-Stroud, Joyce Cohen, Gabriela Pacheco-Sanchez, Hongmei Gao, Zhuyun Liu, Christopher B. Fox, Sanjeev Gumber, Junfei Wei, Nathan Eisel, Maria Elena Bottazzi, Rachelle L. Stammen, Jennifer S. Wood, Shannon Kirejczyk, Bin Zhan, Muhammad Bilal Latif, Peter J. Hotez, Kirk Easley, Ulrich Strych, Jeroen Pollet, Mehul S. Suthar, Mark A. Tomai
Publikováno v:
Science immunology. 6(61)
Ongoing SARS-CoV-2 vaccine development is focused on identifying stable, cost-effective, and accessible candidates for global use, specifically in low and middle-income countries. Here, we report the efficacy of a rapidly scalable, novel yeast expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda30568edb257ce26a9cc220f70f562
https://pubmed.ncbi.nlm.nih.gov/34266981
https://pubmed.ncbi.nlm.nih.gov/34266981
Autor:
Glenda Canderan, Gabriela Pacheco Sanchez, Khader Ghneim, Jane M. Heffernan, Slim Fourati, Lalezari Jp, Sabbagh L, Ashish Sharma, Guinevere Q. Lee, Ando D, J Zeidan, Rafick Pierre Sekaly, Rémi Fromentin, Monette G, Robert Balderas, Francesco A. Procopio, Angie Raad, Nicolas Chomont, Clarisse Benne, Steve Deeks
Antiretroviral therapy (ART) fails to fully restore immune function and is not curative. A single infusion of CCR5 gene-edited autologous CD4+ T cells (SB-728-T) led to sustained increases in CD4+ T cell counts, improved T cell homeostasis, and reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5621b0a796d96e0625fcc4ae6ccbdd6e
https://doi.org/10.1101/2021.02.28.433290
https://doi.org/10.1101/2021.02.28.433290