Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Gabriela Melen-Mucha"'
Autor:
Jacek Swietoslawski, Ewelina Motylewska, Jan Komorowski, Henryk Stepien, Gabriela Melen-Mucha, Agata Niedziela, Joanna Gawronska, Hanna Lawnicka
Publikováno v:
Nutrition and Cancer. 68:428-434
Patients with neuroendocrine tumors (NETs), malignancies of rare but still rising incidence, may be a group at higher risk of vitamin D insufficiency. The gastrointestinal tumor prevalence and somatostatin analog (SSA) therapy may cause vitamin D mal
Autor:
Agata Niedziela, Gabriela Melen-Mucha
Publikováno v:
Endocrine Abstracts.
Interferon alpha and rapamycin inhibit the growth of carcinoid and medullary thyroid cancer in vitro
Autor:
Hanna Lawnicka, Paulina Sicińska, Agata Niedziela, Magdalena Kowalewicz-Kulbat, Gabriela Melen-Mucha, Henryk Stepien, Ewelina Motylewska
Publikováno v:
Pharmacological Reports. 66:624-629
Neuroendocrine tumors (NETs) are highly vascularized neoplasms characterized by rising incidence. Moreover, the neuroendocrine cells were shown to express vascular endothelial growth factor (VEGF) and VEGF receptors. Therefore, angiomodulators could
Publikováno v:
Peptides. 38:248-254
Recent studies demonstrate that ghrelin can be an endogenous regulator of angiogenesis. We studied direct effects of human acylated (hAG) and unacylated (hUAG) ghrelin, as well as of rat acylated ghrelin (rAG) on the growth of HECa10 murine endotheli
Autor:
Gabriela Melen-Mucha, Agata Niedziela, Ewelina Motylewska, Hanna Lawnicka, Henryk Stepien, Sławomir Mucha, Jan Komorowski
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 13, Iss 2, Pp 1444-1460 (2012)
International Journal of Molecular Sciences; Volume 13; Issue 2; Pages: 1444-1460
International Journal of Molecular Sciences, Vol 13, Iss 2, Pp 1444-1460 (2012)
International Journal of Molecular Sciences; Volume 13; Issue 2; Pages: 1444-1460
Background: Gastro-entero-pancreatic/neuroendocrine (NET) tumors are highly vascularized neoplasms. However, our knowledge concerning circulating levels of the angiogenic factors in NET patients still remains insufficient. Methods: The aim of this st
Autor:
Henryk Stepien, Hanna Lawnicka, Ewelina Motylewska, Jan Komorowski, Gabriela Melen-Mucha, Agnieszka Siejka
Publikováno v:
ResearcherID
Some of the antagonists of growth hormone-releasing hormone (GHRH) are able to inhibit the growth of various experimental human cancers. The antitumor effects of first antagonists seemed to be dependent mainly on the disruption of pituitary secretion
Autor:
Dorota Kierszniewska-Stepien, Hanna Lawnicka, Gabriela Melen-Mucha, Jan Komorowski, Henryk Stepien
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 1:237-254
Somatostatin (SS) was originally discovered as a hypothalamic neurohormone which inhibits growth hormone secretion. The synthesis of the first two metabolically stabilized and more potent SS analogs, octreotide and lanreotide leads to the establishme
Publikováno v:
Current Opinion in Pharmacology. 4:608-613
Somatostatin (SST) was firstly discovered as a hypothalamic hormone inhibiting GH secretion. Despite its broad inhibitory effects on both endocrine and exocrine secretions, natural SST has limited therapeutic potential owing to its short plasma half-
Autor:
Agata Niedziela, Gabriela Melen-Mucha
Publikováno v:
Endocrine Abstracts.
Publikováno v:
Cellular and Molecular Life Sciences (CMLS). 55:506-510
Oestrogens are known to enhance angiotensin biosynthesis by increasing the elaboration of its precursor, angiotensinogen. On the other hand, we found that inhibition of angiotensin-converting enzyme (ACE) suppressed the proliferative response of the