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of 5
pro vyhledávání: '"Gabriela M Cash"'
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma
Autor:
Nathan M Krah, Jean-Paul De La O, Galvin H Swift, Chinh Q Hoang, Spencer G Willet, Fong Chen Pan, Gabriela M Cash, Mary P Bronner, Christopher VE Wright, Raymond J MacDonald, L Charles Murtaugh
Publikováno v:
eLife, Vol 4 (2015)
Understanding the initiation and progression of pancreatic ductal adenocarcinoma (PDAC) may provide therapeutic strategies for this deadly disease. Recently, we and others made the surprising finding that PDAC and its preinvasive precursors, pancreat
Externí odkaz:
https://doaj.org/article/d0d6122d6cf14e708396125de0b4ad79
Publikováno v:
Developmental Biology. 391(1):89-98
Pancreatic exocrine and endocrine lineages arise from multipotent pancreatic progenitor cells (MPCs). Exploiting the mechanisms that govern expansion and differentiation of these cells could enhance efforts to generate β-cells from stem cells. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2efa0c90aa649779d51487d1440340d
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma
Autor:
Chinh Q. Hoang, Spencer G. Willet, Raymond J. MacDonald, Jean-Paul De La O, Gabriela M Cash, Christopher V.E. Wright, L. Charles Murtaugh, Nathan M. Krah, Fong Chen Pan, Galvin H. Swift, Mary P. Bronner
Publikováno v:
eLife, Vol 4 (2015)
Pancreatic cancer is one of the most lethal forms of cancer, with fewer than 20% of people surviving for longer than twelve months after diagnosis. Two types of genetic mutation play important roles in pancreatic cancer. First, genes called oncogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74db9b5261f92b09fa2103574a0f3ce9
https://doi.org/10.7554/elife.07125
https://doi.org/10.7554/elife.07125
Autor:
Christopher V.E. Wright, Fong Chen Pan, Jean-Paul De La O, L. Charles Murtaugh, Chinh Q. Hoang, Raymond J. MacDonald, Galvin H. Swift, Gabriela M Cash, Spencer G. Willet, Mary P. Bronner, Nathan M. Krah
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e11b4c52f205847e26b0428ab9484f
https://doi.org/10.7554/elife.07125.028
https://doi.org/10.7554/elife.07125.028
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(31)
The Drosophila porcupine gene is required for secretion of wingless and other Wnt proteins, and sporadic mutations in its unique human ortholog, PORCN , cause a pleiotropic X-linked dominant disorder, focal dermal hypoplasia (FDH, also known as Goltz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f940ef154ab5f023be93b3a380825c
https://pubmed.ncbi.nlm.nih.gov/21768372
https://pubmed.ncbi.nlm.nih.gov/21768372