Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Gabriela Leusink-Ionescu"'
Autor:
Jean-Paul G. Seerden, Titia E. Woudenberg-Vrenken, Bas Dros, Richard M. Kellogg, Grietje Molema, Gabriela Leusink-Ionescu, Jan A. A. M. Kamps
Publikováno v:
Bioorganic & Medicinal Chemistry Letters, 24(15), 3412-3418. American Chemical Society
The synthesis and structure-activity relationships of novel 4-(4 '-fluorophenyl)imidazoles as selective p38 alpha MAPK, CK1 delta and JAK2 inhibitors with improved water solubility are described. Microwave-assisted multicomponent reactions afforded 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd6b662737c14cd83ad04b9a27414b3
https://doi.org/10.1016/j.bmcl.2014.05.080
https://doi.org/10.1016/j.bmcl.2014.05.080
Autor:
Bas Dros, Grietje Molema, Gabriela Leusink-Ionescu, Catherine Saccavini, Robin Leguijt, Jean-Paul G. Seerden, Richard M. Kellogg, Jan A. A. M. Kamps, Titia E. Woudenberg-Vrenken, Edith Gelens
Publikováno v:
Bioorganic & Medicinal Chemistry Letters, 24(5), 1352-1357. American Chemical Society
The design, synthesis and biological evaluation of novel triazolyl p38 alpha MAPK inhibitors with improved water solubility for formulation in cationic liposomes (SAINT-O-Somes) targeted at diseased endothelial cells is described. Water-solubilizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca940e89d6bc5797224adde05e2c54e4
https://doi.org/10.1016/j.bmcl.2014.01.034
https://doi.org/10.1016/j.bmcl.2014.01.034