Adsorption and Inactivation of SARS-CoV-2 on the Surface of Anatase TiO2(101)

Autor: Mona Kohantorabi, Michael Wagstaffe, Marcus Creutzburg, Aldo Ugolotti, Satishkumar Kulkarni, Arno Jeromin, Tobias Krekeler, Martin Feuerherd, Alexander Herrmann, Gregor Ebert, Ulrike Protzer, Gabriela Guédez, Christian Löw, Roland Thuenauer, Christoph Schlueter, Andrei Gloskovskii, Thomas F. Keller, Cristiana Di Valentin, Andreas Stierle, Heshmat Noei

Publikováno v: ACS Applied Materials & Interfaces. 15:8770-8782

We investigated the adsorption of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), the virus responsible for the current pandemic, on the surface of the model catalyst TiO2(101) using atomic force microscopy, transmission electron micro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ce513c507a9f4b5b84250321859ec6
https://doi.org/10.1021/acsami.2c22078

Crystal structure of dimeric Synechococcus spermidine synthase with bound polyamine substrate and product

Autor: Gabriela Guédez, Saija Sirén, Aran Incharoensakdi, Apiradee Pothipongsa, Saowarath Jantaro, Arto Liljeblad, Tiina A. Salminen

Publikováno v: Biochemical Journal. 476:1009-1020

Spermidine is a ubiquitous polyamine synthesized by spermidine synthase (SPDS) from the substrates, putrescine and decarboxylated S-adenosylmethionine (dcAdoMet). SPDS is generally active as homodimer, but higher oligomerization states have been repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f784fde3a6f1e02402666598f8fe4579
https://doi.org/10.1042/bcj20180811

Structural and Biomolecular Analyses of Borrelia burgdorferi BmpD Reveal a Substrate-Binding Protein of an ABC-Type Nucleoside Transporter Family

Autor: Julia, Cuellar, Mia, Åstrand, Heli, Elovaara, Annukka, Pietikäinen, Saija, Sirén, Arto, Liljeblad, Gabriela, Guédez, Tiina A, Salminen, Jukka, Hytönen

Publikováno v: Infection and Immunity

Borrelia burgdorferi sensu lato, the causative agent of tick-borne Lyme borreliosis (LB), has a limited metabolic capacity and needs to acquire nutrients, such as amino acids, fatty acids, and nucleic acids, from the host environment. Using X-ray cry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c7a7b52b62911294c6d8b35a15d1208c
https://pubmed.ncbi.nlm.nih.gov/31988175

Mapping the interaction site and effect of the Siglec-9 inflammatory biomarker on human primary amine oxidase

Autor: Leonor Lopes de Carvalho, Tiina A. Salminen, Gérard Vergoten, Gabriela Guédez, Jérôme de Ruyck, Sirpa Jalkanen, Heli Elovaara

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, Scientific Reports, 8 (1), pp.2086. ⟨10.1038/s41598-018-20618-4⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, 2018, Scientific Reports, 8 (1), pp.2086. ⟨10.1038/s41598-018-20618-4⟩

Human primary amine oxidase (hAOC3), also known as vascular adhesion protein 1, mediates leukocyte rolling and trafficking to sites of inflammation by a multistep adhesion cascade. hAOC3 is absent on the endothelium of normal tissues and is kept upre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233a5f4880ab5d324688b921626e58c6
https://hal.univ-lille.fr/hal-03203814/file/s41598-018-20618-4.pdf

Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis

Autor: Marco Strohmeier, Volker Windeisen, Irmgard Sinning, Gwyndaf Evans, Matthew J. Rodrigues, Steven E. Ealick, Yang Zhang, Jeremiah Hanes, Ivo Tews, Tadhg P. Begley, Gabriela Guédez, Antoine Royant, Stefan Fabian Weber

Publikováno v: Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2017, 13 (3), pp.290-294. ⟨10.1038/nchembio.2273⟩
Nature Chemical Biology, 2017, 13 (3), pp.290-294. ⟨10.1038/nchembio.2273⟩

International audience; Substrate channeling has emerged as a common mechanism for enzymatic intermediate transfer. A conspicuous gap in knowledge concerns the use of covalent lysine imines in the transfer of carbonyl-group-containing intermediates,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34970f0c3eeef2d7aad4fa6584bb26f0
https://hal.univ-grenoble-alpes.fr/hal-01487798/document