Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gabriela Galicia-Vazquez"'
Autor:
Katie Fooks, Gabriela Galicia-Vazquez, Victor Gife, Alejandro Schcolnik-Cabrera, Zaynab Nouhi, William W. L. Poon, Vincent Luo, Ryan N. Rys, Raquel Aloyz, Alexandre Orthwein, Nathalie A. Johnson, Laura Hulea, Francois E. Mercier
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Acute myeloid leukemia (AML) is an aggressive hematological cancer resulting from uncontrolled proliferation of differentiation-blocked myeloid cells. Seventy percent of AML patients are currently not cured with available treatmen
Externí odkaz:
https://doaj.org/article/e6bb8583447d4acda27cf156d9e76eb8
Autor:
Katie Fooks, Gabriela Galicia-Vazquez, Alejandro Schcolnik-Cabrera, Victor Gife, Zaynab Nouhi, William WL Poon, Vincent Luo, Raquel Aloyz, Alexandre Orthwein, Laura Hulea, François E Mercier
Background Acute myeloid leukemia (AML) is an aggressive hematological cancer resulting from uncontrolled proliferation of differentiation-blocked myeloid cells. Seventy percent of AML patients are currently not cured with available treatments, highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d70d8c735ce142ceb9de8e4e58484e9
https://doi.org/10.21203/rs.3.rs-1696855/v1
https://doi.org/10.21203/rs.3.rs-1696855/v1
Autor:
Nathalie A. Johnson, Maja Jankovic, Selin Jessa, Ioannis Ragoussis, William Poon, Kolja Eppert, Yu Chang Wang, Francois Mercier, Gabriela Galicia Vazquez, Alexandre Bazinet, Claudia L. Kleinman, Katharine Fooks, Isabella Iasenza, Patricia Arreba-Tutusaus, Sarit Assouline, Samantha Worme
Publikováno v:
Blood. 136:1-1
Introduction: Relapse remains the major cause of mortality in acute myeloid leukemia (AML). Prior work indicates that a rare subset of leukemic stem cells (LSCs) self-renew and propagate AML. However, characterizing LSCs is complicated by their scarc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a38295244943ddb15e9d1b1b00902da
https://doi.org/10.1182/blood-2020-143221
https://doi.org/10.1182/blood-2020-143221
Autor:
Jason Sadek, Imed-Eddine Gallouzi, Jerry Pelletier, Arnim Pause, Sergio Di Marco, Gabriela Galicia Vazquez, Zvi Cramer
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Cachexia is a deadly muscle wasting syndrome that arises under conditions linked to chronic inflammation, such as cancer. Cytokines, including interferon γ (IFNγ), tumor necrosis factor α (TNFα) and interleukin-6 (IL-6), and their downstream effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f560ecb6777dc36247720390c7225589
https://doi.org/10.1038/s41598-018-26625-9
https://doi.org/10.1038/s41598-018-26625-9
Autor:
Jennifer Chu, Gabriela Galicia-Vázquez, Regina Cencic, John R. Mills, Alexandra Katigbak, John A. Porco Jr., Jerry Pelletier
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2340-2347 (2016)
Targeting translation initiation is an emerging anti-neoplastic strategy that capitalizes on de-regulated upstream MAPK and PI3K-mTOR signaling pathways in cancers. A key regulator of translation that controls ribosome recruitment flux is eukaryotic
Externí odkaz:
https://doaj.org/article/491aa4c375854826a5c19588971919ab
Autor:
Gabriela Galicia-Vázquez, Raquel Aloyz
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Chronic Lymphocytic Leukemia (CLL) is an incurable disease, characterized by the accumulation of malignant B-lymphocytes in the blood stream (quiescent state) and homing tissues (where they can proliferate). In CLL, the targeting of B-cell receptor s
Externí odkaz:
https://doaj.org/article/dd3017b8e48f438aac4f33fb4ff6c8b2
Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.
Autor:
Gabriela Galicia-Vázquez, Sergio Di Marco, Xian J Lian, Jennifer F Ma, Imed E Gallouzi, Jerry Pelletier
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87237 (2014)
Gene expression during muscle cell differentiation is tightly regulated at multiple levels, including translation initiation. The PI3K/mTOR signalling pathway exerts control over protein synthesis by regulating assembly of eukaryotic initiation facto
Externí odkaz:
https://doaj.org/article/0df4c202c8244fadac522a12b61024a8
Autor:
Regina Cencic, Marilyn Carrier, Gabriela Galicia-Vázquez, Marie-Eve Bordeleau, Rami Sukarieh, Annie Bourdeau, Brigitte Brem, Jose G Teodoro, Harald Greger, Michel L Tremblay, John A Porco, Jerry Pelletier
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5223 (2009)
Flavaglines are a family of natural products from the genus Aglaia that exhibit anti-cancer activity in vitro and in vivo and inhibit translation initiation. They have been shown to modulate the activity of eIF4A, the DEAD-box RNA helicase subunit of
Externí odkaz:
https://doaj.org/article/66014db3c75f46fdb41be1ca1ac3d42b