Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Gabriela D A Guardia"'
Autor:
Maria Virginia Giolito, Serguei Bodoirat, Theo La Rosa, Mathieu Reslinger, Gabriela D. A. Guardia, Jana Mourtada, Leo Claret, Alain Joung, Pedro A. F. Galante, Luiz O. F. Penalva, Michelina Plateroti
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Colorectal cancers (CRCs) are highly heterogeneous and show a hierarchical organization, with cancer stem cells (CSCs) responsible for tumor development, maintenance, and drug resistance. Our previous studies showed the importance of thyroid
Externí odkaz:
https://doaj.org/article/47036ca150204b2daf31ed90fa454bc6
Autor:
Rodrigo A. S. Barreiro, Gabriela D. A. Guardia, Fabiana M. Meliso, Xiufen Lei, Wei-Qing Li, Andre Savio, Martin Fellermeyer, Helena B. Conceição, Rafael L. V. Mercuri, Tesha Landry, Mei Qiao, Lorea Blazquez, Jernej Ule, Luiz O.F. Penalva, Pedro A. F. Galante
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 311-322 (2023)
The exon junction complex (EJC) plays key roles throughout the lifespan of RNA and is particularly relevant in the nervous system. We investigated the roles of two EJC members, the paralogs MAGOH and MAGOHB, with respect to brain tumour development.
Externí odkaz:
https://doaj.org/article/4fd5893722cd47b3862c3d6e6e3796d7
Autor:
Rafael L. V. Mercuri, Helena B. Conceição, Gabriela D. A. Guardia, Gabriel Goldstein, Maria D. Vibranovski, Ludwig C. Hinske, Pedro A. F. Galante
Publikováno v:
Mobile DNA, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Reverse-transcribed gene copies (retrocopies) have emerged as major sources of evolutionary novelty. MicroRNAs (miRNAs) are small and highly conserved RNA molecules that serve as key post-transcriptional regulators of gene express
Externí odkaz:
https://doaj.org/article/4554800633104bd8aab90d42a4f8c5d9
Autor:
Maria Virginia Giolito, Théo La Rosa, Diana Farhat, Serguei Bodoirat, Gabriela D. A. Guardia, Claire Domon‐Dell, Pedro A. F. Galante, Jean‐Noel Freund, Michelina Plateroti
Publikováno v:
Molecular Oncology, Vol 16, Iss 22, Pp 3975-3993 (2022)
The THRA gene, encoding the thyroid hormone nuclear receptor TRα1, is expressed in an increasing gradient at the bottom of intestinal crypts, overlapping with high Wnt and Notch activities. Importantly, THRA is upregulated in colorectal cancers, par
Externí odkaz:
https://doaj.org/article/9088fcb36d304e73a6be70f48360ab38
Autor:
Pedro A. C. Costa, Walison N. Silva, Pedro H. D. M. Prazeres, Caroline C. Picoli, Gabriela D. A. Guardia, Alinne C. Costa, Mariana A. Oliveira, Pedro P. G. Guimarães, Ricardo Gonçalves, Mauro C. X. Pinto, Jaime H. Amorim, Vasco A. C. Azevedo, Rodrigo R. Resende, Remo C. Russo, Thiago M. Cunha, Pedro A. F. Galante, Akiva Mintz, Alexander Birbrair
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-41 (2021)
Abstract Sensory neurons have recently emerged as components of the tumor microenvironment. Nevertheless, whether sensory neuronal activity is important for tumor progression remains unknown. Here we used Designer Receptors Exclusively Activated by a
Externí odkaz:
https://doaj.org/article/3bc21826b70242beab95f440ca474ea2
Autor:
Adam Kosti, Patricia Rosa de Araujo, Wei-Qing Li, Gabriela D. A. Guardia, Jennifer Chiou, Caihong Yi, Debashish Ray, Fabiana Meliso, Yi-Ming Li, Talia Delambre, Mei Qiao, Suzanne S. Burns, Franziska K. Lorbeer, Fanny Georgi, Markus Flosbach, Sarah Klinnert, Anne Jenseit, Xiufen Lei, Carolina Romero Sandoval, Kevin Ha, Hong Zheng, Renu Pandey, Aleksandra Gruslova, Yogesh K. Gupta, Andrew Brenner, Erzsebet Kokovay, Timothy R. Hughes, Quaid D. Morris, Pedro A. F. Galante, Stefano Tiziani, Luiz O. F. Penalva
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-32 (2020)
Abstract Background RNA-binding proteins (RBPs) function as master regulators of gene expression. Alterations in RBP expression and function are often observed in cancer and influence critical pathways implicated in tumor initiation and growth. Ident
Externí odkaz:
https://doaj.org/article/351c24c3b258441fade10ab7e34c510d
Autor:
Anacleto Silva de Souza, Vitor Martins de Freitas Amorim, Gabriela D. A. Guardia, Filipe F. dos Santos, Henning Ulrich, Pedro A. F. Galante, Robson Francisco de Souza, Cristiane Rodrigues Guzzo
Publikováno v:
Viruses, Vol 14, Iss 4, p 827 (2022)
Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) are constantly threatening global public health. With no end date, the pandemic persists with the emergence of novel variants that threaten the effectiveness
Externí odkaz:
https://doaj.org/article/2ee8e533b09f45e595463ddc26b5fdc2
Autor:
Mirella Baroni, Gabriela D. A. Guardia, Xiufen Lei, Adam Kosti, Mei Qiao, Tesha Landry, Karl Mau, Pedro A. F. Galante, Luiz O. F. Penalva
Publikováno v:
Cells, Vol 11, Iss 1, p 56 (2021)
Medulloblastoma is the most common malignant brain tumor in children. Treatment with surgery, irradiation, and chemotherapy has improved survival in recent years, but patients are frequently left with devastating neurocognitive and other sequelae. Pa
Externí odkaz:
https://doaj.org/article/142f5cc06b774d00ab977b226c24654e
Autor:
Galante, Gabriela D. A. Guardia, Rafaella G. Naressi, Vanessa C. Buzzato, Juliana B. da Costa, Ilana Zalcberg, Jordana Ramires, Bettina Malnic, Luciana M. Gutiyama, Pedro A. F.
Publikováno v:
Cancers; Volume 15; Issue 12; Pages: 3073
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with a 5-year overall survival rate of approximately 30%. Despite recent advances in therapeutic options, relapse remains the leading cause of death and poor survival o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::fbe0fc2d59fffc558f04d525eec2f278
Autor:
Anacleto Silva de Souza, Vitor Martins de Freitas Amorim, Gabriela D. A. Guardia, Felipe R. C. dos Santos, Filipe F. dos Santos, Robson Francisco de Souza, Guilherme de Araujo Juvenal, Yihua Huang, Pingju Ge, Yinan Jiang, Coco Li, Prajwal Paudel, Henning Ulrich, Pedro A. F. Galante, Cristiane Rodrigues Guzzo
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is evolving with mutations in the spike protein, especially in the receptor-binding domain (RBD). The failure of public health measures in some countries to contain the spread of the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fda50c166a72fa5a399212bb620a973
https://doi.org/10.1021/acsomega.1c07240
https://doi.org/10.1021/acsomega.1c07240