Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gabriela B. Plata"'
Autor:
Aitor Urosa, Isidro S. Marcos, David Díez, Anna Lithgow, Gabriela B. Plata, José M. Padrón, Pilar Basabe
Publikováno v:
Marine Drugs, Vol 13, Iss 4, Pp 2407-2423 (2015)
The first synthesis of Luffarin I, sesterterpenolide isolated from sponge Luffariella geometrica, has been accomplished from commercially available sclareol. The key strategy involved in this synthesis is the diastereoselective reduction of an interm
Externí odkaz:
https://doaj.org/article/3cda19a8e89242b5af5add8d57c678f4
Autor:
Paloma Begines, Gabriela B. Plata, José G. Fernández-Bolaños, Inés Maya, Ana Oliete, José M. Padrón, Óscar López
Publikováno v:
Future Medicinal Chemistry. 10:319-334
Aim: The increasing number of cancer cases has stimulated researchers to seek for novel approaches. We have combined two bioactive moieties: a polyphenolic scaffold and an organoselenium motif. Four different families (isothiocyanates/thioureas, and
Autor:
Óscar López, José G. Fernández-Bolaños, Jacob Ingemar Olsen, Mikael Bols, José M. Padrón, Gabriela B. Plata
Publikováno v:
European Journal of Medicinal Chemistry. 123:155-160
Herein we report the synthesis of N-alkylated deoxynojirimycin derivatives decorated with a selenoureido motif at the hydrocarbon tether as an example of unprecedented multitarget agents. Title compounds were designed as dual drugs for tackling simul
Autor:
Ángel Trigos, José J. Fernández, César Espinoza, Alla V. Shnyreva, Alan Couttolenc, Manuel Norte, Gabriela B. Plata, José M. Padrón
Publikováno v:
Pharmaceutical Biology. 54:1392-1397
It is well known that marine fungi are an excellent source of biologically active secondary metabolites, and by 2011, it was reported that over 400 bioactive metabolites were derived from marine fungi.This study establishes the basis for future resea
Autor:
Isabel Cuadrado, Daniel Nieto, Gabriela B. Plata, Fernando Carrillo-Hermosilla, Antonio Antiñolo, José M. Padrón, Sonia Bruña, Ana Ma González-Vadillo, Josefina Perles
Publikováno v:
Organometallics. 34:5407-5417
The potential of structurally new ferrocene-functionalized guanidines as redox-active precursors for the synthesis of heterometallic platinum(II)–guanidine complexes with anticancer activity was studied. To this end, an atom-economical catalytic ap
Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A
Publikováno v:
Molecular Diversity. 20:369-377
Natural sesterterpenolides, luffarin I and luffarin A, from Luffariella geometrica have been synthesized, and this is the first reported synthesis of luffarin A. The Yamaguchi esterification of the nor-diterpenic fragment, obtained from 2.8-15μM, wi
Autor:
Pilar Basabe, Anna M. Lithgow, David Díez, Aitor Urosa, José M. Padrón, Gabriela B. Plata, Isidro S. Marcos
Publikováno v:
Marine Drugs
Volume 13
Issue 4
Pages 2407-2423
Marine Drugs, Vol 13, Iss 4, Pp 2407-2423 (2015)
Volume 13
Issue 4
Pages 2407-2423
Marine Drugs, Vol 13, Iss 4, Pp 2407-2423 (2015)
The first synthesis of Luffarin I, sesterterpenolide isolated from sponge Luffariella geometrica, has been accomplished from commercially available sclareol. The key strategy involved in this synthesis is the diastereoselective reduction of an interm
Autor:
Marco A Jiménez, Gabriela B. Plata, Jorge Triana, María F Pérez-Pujols, José L. Eiroa, Diana C Rodríguez, Quírico A. Castillo, Ernesto Abel-Santos, José M. Padrón, Luis A. Báez
Publikováno v:
Pharmacognosy Journal. 7:178-181
Objective: To isolate the chemical constituents of the aerial parts from Eupatorium illitum, elucidate their structures and evaluate their antiproliferative activity on human cancer cell lines. Materials and Methods: The ethanolic extract of Eupatori
Autor:
Vivek K. Gupta, Narsidas J. Parmar, Balvantsingh M. Labana, Gabriela B. Plata, Rajni Kant, Tushar R. Sutariya, José M. Padrón
Publikováno v:
New Journal of Chemistry. 39:2657-2668
Syntheses of some new pyrrolo-fused pyrrolo[1,2-a] indole derivatives have been achieved by combining N-allyl-indole-2-carbaldehyde with a variety of N-alkyl-glycine esters as well as tetrahydroisoquinolines in an ionic liquid, triethylammonium aceta
Autor:
Gabriela B. Plata, Elena M. Sánchez-Fernández, Carmen Ortiz Mellet, José M. Padrón, Rocío Rísquez-Cuadro, José M. García Fernández, Rita Gonçalves-Pereira
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The synthesis of a complete series of cyclic carbamate-type sp-iminosugar N-, S-, O- and C-octyl pseudoglycosides related to nojirimycin, mannojirimycin and galactonojirimycin, all having the α-pseudoanomeric configuration, is reported. The gem-diam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f26f01b2eae1be956f6db06f1028d3
http://hdl.handle.net/10261/190260
http://hdl.handle.net/10261/190260