Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gabriela Alejandra Eppel"'
Autor:
Maarten P. Koeners, David M. Russell, Amany Abdelkader, Simon C. Malpas, Gabriela Alejandra Eppel, Roger G. Evans, Connie P. C. Ow, John Ludbrook
Publikováno v:
American Journal of Physiology-Renal Physiology. 304:F1471-F1480
The precise roles of hypoxia in the initiation and progression of kidney disease remain unresolved. A major technical limitation has been the absence of methods allowing long-term measurement of kidney tissue oxygen tension (Po2) in unrestrained anim
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 300:R931-R940
To better understand what makes the kidney susceptible to tissue hypoxia, we compared, in the rabbit kidney and hindlimb, the ability of feedback mechanisms governing oxygen consumption (V̇o2) and oxygen delivery (Do2) to attenuate tissue hypoxia du
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 38:247-254
Summary 1. Oxygen tension (PO2) in renal cortical tissue can remain relatively constant when renal blood flow changes in the physiological range, even when changes in renal oxygen delivery (DO2) and oxygen consumption (VO2) are mismatched. In the cur
Multiple mechanisms act to maintain kidney oxygenation during renal ischemia in anesthetized rabbits
Autor:
Sandra L. Burke, Sylvia Michaels, Joan F Carroll, Gabriela Alejandra Eppel, Paul M. O'Connor, Geoffrey A. Head, Roger G. Evans, Mehdi Nematbakhsh
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F1235-F1243
We examined the mechanisms that maintain stable renal tissue Po2 during moderate renal ischemia, when changes in renal oxygen delivery (Ḋo2) and consumption (V̇o2) are mismatched. When renal artery pressure (RAP) was reduced progressively from 80
Autor:
Daryl O. Schwenke, Gabriela Alejandra Eppel, James T. Pearson, Mikiyasu Shirai, Roger G. Evans, Hirotsugu Tsuchimochi, Keiji Umetani, Amanda J. Edgley
Publikováno v:
Monash University
1. Real-time imaging of the vascular networks of any organ system in vivo is possible with synchrotron radiation (SR) angiography. In this review, we discuss the advantages of SR angiography over clinical X-ray imaging and other non-ionizing imaging
Autor:
Paul M. O'Connor, Gabriela Alejandra Eppel, Chai Ling Leong, Warwick P Anderson, Roger G. Evans
Publikováno v:
Monash University
Background/Aims: The validity of fluorescence optodes for measurement of renal cortical tissue oxygen tension was tested by comparison with Clark electrodes. Methods: We varied renal blood flow and inspired O2 content in anaesthetized rabbits while s
Publikováno v:
British Journal of Pharmacology. 149:523-531
Background and purpose: Our knowledge of the effects of P2-receptor activation on renal vascular tone comes mostly from in vitro models. We aimed to characterise the pharmacology of ATP in the renal circulation in vivo. Experimental approach: In pent
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 32:400-409
1. It is well established that pressure natriuresis plays a key role in long-term blood pressure regulation, but our understanding of the mechanisms underlying this process is incomplete. 2. Pressure natriuresis is chiefly mediated by inhibition of t
Autor:
Roger G. Evans, Niwanthi W. Rajapakse, Gabriela Alejandra Eppel, Rebecca Lee Flower, Kate M. Denton, Simon C. Malpas
Publikováno v:
Pfl�gers Archiv - European Journal of Physiology. 449:143-149
We examined the roles of cyclooxygenase products and of interactions between the cyclooxygenase and nitric oxide systems in the mechanisms underlying the relative insensitivity of medullary perfusion to renal nerve stimulation (RNS) in anaesthetized
Publikováno v:
Journal of Hypertension. 22:1439-1451
There is much evidence that the medullary circulation plays a key role in regulating renal salt and water handling and, accordingly, the long-term level of arterial pressure. It has also recently become clear that various regulatory factors can affec