Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Gabriel Zimmerman"'
Autor:
Igor Ruvinsky, Maximiliano Katz, Avigail Dreazen, Yuval Gielchinsky, Ann Saada, Nanette Freedman, Eyal Mishani, Gabriel Zimmerman, Judith Kasir, Oded Meyuhas
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5618 (2009)
BACKGROUND: Mice, whose ribosomal protein S6 cannot be phosphorylated due to replacement of all five phosphorylatable serine residues by alanines (rpS6(P-/-)), are viable and fertile. However, phenotypic characterization of these mice and embryo fibr
Externí odkaz:
https://doaj.org/article/3f4b80cffa164f35b31eab7280f36765
Autor:
Hermona Soreq, Itamar Aroch, Alon Friedman, Gabriel Zimmerman, Orit Chai, A. Sommer, Merav H. Shamir, Yael Merbl
Publikováno v:
Journal of Veterinary Internal Medicine
Background Idiopathic and acquired epilepsy are common in dogs. Up to 30% of these dogs are refractory to pharmacological treatment. Accumulating experimental evidence indicates that brain immune response and presence of inflammatory mediators decrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ae22b9ee1d405c1873256c17258349
https://doi.org/10.1111/jvim.12462
https://doi.org/10.1111/jvim.12462
Publikováno v:
Annals of the New York Academy of Sciences. 1148:269-281
Mammalian stress responses present a case study for investigating alternative splicing reactions in general, and changes in acetylcholinesterase (AChE) gene expression in particular, under endangered homeostasis. Acetylcholine (ACh) is a major regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18981d62192a3a71a8a7a327418b7f22
https://doi.org/10.1196/annals.1410.001
https://doi.org/10.1196/annals.1410.001
Autor:
Hermona Soreq, Uwe Heinemann, Marleisje Njunting, Sebastian Ivens, Christoph J. Behrens, Alon Friedman, Miriam Gross, Else A. Tolner, Gabriel Zimmerman
Publikováno v:
European Journal of Neuroscience. 27:965-975
The entorhinal cortex (EC) plays an important role in temporal lobe epilepsy. Under normal conditions, the enriched cholinergic innervation of the EC modulates local synchronized oscillatory activity; however, its role in epilepsy is unknown. Enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3a71929890e6c61f81800ed0fdb910
https://doi.org/10.1111/j.1460-9568.2008.06070.x
https://doi.org/10.1111/j.1460-9568.2008.06070.x
Autor:
Amir Dori, Naomi Melamed-Book, Jonathan Cohen, Gabriel Zimmerman, Hermona Soreq, Alon Friedman
Publikováno v:
Hippocampus. 18:182-192
In the adult murine hippocampus, dentate gyrus (DG), neurogenesis and neural cell death are thought to affect learning and memory in incompletely understood mechanism(s). Because cholinergic neurotransmission influences both of these functions, we hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37647a0ce7765cd8ad0e4911eb9fa9ee
https://doi.org/10.1002/hipo.20381
https://doi.org/10.1002/hipo.20381
Autor:
Hermona Soreq, Gabriel Zimmerman
Publikováno v:
Cell and Tissue Research. 326:655-669
Termination of synaptic transmission by neurotransmitter hydrolysis is a substantial characteristic of cholinergic synapses. This unique termination mechanism makes acetylcholinesterase (AChE), the enzyme in charge of executing acetylcholine breakdow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1114c5db35a1d6199a5e8010949040ee
https://doi.org/10.1007/s00441-006-0239-8
https://doi.org/10.1007/s00441-006-0239-8
Autor:
Hermona Soreq, Gabriel Zimmerman
Publikováno v:
Journal of Molecular Neuroscience. 30:197-200
Stress insults induce hyperexcitation of cholinergic circuits, both peripherally in the sympathetic pathway (Tracey, 2002) and at the central nervous system (CNS) (Sapolsky, 1996). This reaction can serve to ensure survival but might also entail a ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e2f94c68eff2328858d36394f1c724
https://doi.org/10.1385/jmn:30:1:197
https://doi.org/10.1385/jmn:30:1:197
Autor:
Adi Alkalay, Gil D. Rabinovici, Hermona Soreq, Gabriel Zimmerman, Neha Agarwal, William J. Jagust, Daniela Kaufer, Bruce L. Miller
Publikováno v:
Current Alzheimer research, vol 10, iss 1
BackgroundPrevious studies have demonstrated alterations in the peripheral cholinergic system in Alzheimer's disease (AD), though results have been inconsistent and not linked to in vivo biomarkers of pathology. We examined the relationship between a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe2a9245ceaf656cec6849304401d3a
https://escholarship.org/uc/item/9jn2m829
https://escholarship.org/uc/item/9jn2m829
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(52)
Stress induces long-lasting changes in neuronal gene expression and cholinergic neurotransmission, but the underlying mechanism(s) are incompletely understood. Here, we report that chromatin structure and histone modifications are causally involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0feb21752f1a094cfa0f481367f6bddf
https://pubmed.ncbi.nlm.nih.gov/23236169
https://pubmed.ncbi.nlm.nih.gov/23236169
Autor:
Gabriel Zimmerman, Orit Chai, Merav H. Shamir, Alon Friedman, Adi Sommer, Tali Bdolah-Abram, Hermona Soreq, Itamar Aroch
Publikováno v:
Veterinary journal (London, England : 1997). 198(1)
Recent studies in animal models have focused on the role of cholinergic elements, mainly acetylcholinesterase (AChE) and the ‘readthrough’ acetylcholinesterase isoform (AChE-R), in seizures. A prospective double-masked study was conducted to asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018a76fa936a09cfee90b2cea1b74ebb
https://pubmed.ncbi.nlm.nih.gov/23988333
https://pubmed.ncbi.nlm.nih.gov/23988333