Grandmaternal cells in cord blood

Autor: Karlin R. Karlmark, Marina El Haddad, Xavier-Côme Donato, Gabriel V. Martin, Florence Bretelle, Nathalie Lesavre, Jean-François Cocallemen, Marielle Martin, Christophe Picard, Tiffany Albentosa, Jean Roudier, Raoul Desbriere, Nathalie C. Lambert

Publikováno v: EBioMedicine, Vol 74, Iss , Pp 103721- (2021)

Abstracts: Background: During pregnancy a feto-maternal exchange of cells through the placenta conducts to maternal microchimerism (Mc) in the child and fetal Mc in the mother. Because of this bidirectional traffic of cells, pregnant women have also

Externí odkaz: https://doaj.org/article/a8ab16279e7f43f798684e88bac4b0d9

Evaluation of X Chromosome Inactivation with Respect to HLA Genetic Susceptibility in Rheumatoid Arthritis and Systemic Sclerosis.

Autor: Sami B Kanaan, Onur E Onat, Nathalie Balandraud, Gabriel V Martin, J Lee Nelson, Doua F Azzouz, Isabelle Auger, Fanny Arnoux, Marielle Martin, Jean Roudier, Tayfun Ozcelik, Nathalie C Lambert

Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0158550 (2016)

Autoimmune diseases, including rheumatoid arthritis (RA) and systemic sclerosis (SSc) are characterized by a strong genetic susceptibility from the Human Leucocyte Antigen (HLA) locus. Additionally, disorders of epigenetic processes, in particular no

Externí odkaz: https://doaj.org/article/60523377c79c49cd81c5fd6f4490636c

Mosaicism of XX and XXY cells accounts for high copy number of Toll like Receptor 7 and 8 genes in peripheral blood of men with Rheumatoid Arthritis

Autor: Cécile Mignon-Ravix, Sami B. Kanaan, Fanny Arnoux, Christophe Picard, Isabelle Auger, Doua F. Azzouz, Nathalie C. Lambert, Marielle Martin, Marina El Haddad, Nathalie Balandraud, Marie F. Hemon, Gabriel V. Martin, Jean Roudier

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.12880. ⟨10.1038/s41598-019-49309-4⟩
Scientific Reports, 2019, 9, pp.12880. ⟨10.1038/s41598-019-49309-4⟩
Scientific Reports, Nature Publishing Group, 2019, 9, pp.12880. ⟨10.1038/s41598-019-49309-4⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

The X chromosome, hemizygous in males, contains numerous genes important to immunological and hormonal function. Alterations in X-linked gene dosage are suspected to contribute to female predominance in autoimmunity. A powerful example of X-linked do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ad3c5aa01ae404f15deca202c33c8a
https://doi.org/10.1038/s41598-019-49309-4

A6.40 Copy number increase ofTLR7andTLR8genes in men with rheumatoid arthritis

Autor: Nathalie C. Lambert, Marielle Martin, Nathalie Balandraud, Isabelle Auger, Doua F. Azzouz, Sami B. Kanaan, Gabriel V. Martin, Christophe Picard, Jean Roudier, Fanny Arnoux

Publikováno v: Annals of the Rheumatic Diseases. 74:A72.1-A72

Background and objectives Men are less often affected by Rheumatoid arthritis (RA) than women. In mice studies, it was shown that a duplication in Toll-like receptor 7 (Tlr7) gene is sufficient to potentiate autoimmunity in males. We therefore propos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5613f1f1bb489ca85f26adedc8086c87
https://doi.org/10.1136/annrheumdis-2015-207259.166

Mosaicism of XX and XXY cells accounts for high copy number of Toll like Receptor 7 and8 genes in peripheral blood of men with Rheumatoid Arthritis.

Autor: Martin, Gabriel V.¹, Kanaan, Sami B.¹, Hemon, Marie F.^1,2, Azzouz, Doua F.¹, El Haddad, Marina¹, Balandraud, Nathalie^1,3, Mignon-Ravix, Cécile^2,4, Picard, Christophe^5,6, Arnoux, Fanny¹, Martin, Marielle¹, Roudier, Jean^1,3, Auger, Isabelle¹, Lambert, Nathalie C.¹ nathalie.lambert@inserm.fr

Publikováno v: Scientific Reports. 9/9/2019, Vol. 9 Issue 1, pN.PAG-N.PAG. 1p.