Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gabriel Stillemans"'
Autor:
Gabriel Stillemans, Adrien Paquot, Giulio G. Muccioli, Emilia Hoste, Nadtha Panin, Anders Åsberg, Jean‐Luc Balligand, Vincent Haufroid, Laure Elens
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 3, Pp 667-679 (2022)
Abstract The purpose of this study was to investigate the potential clinical relevance of estimating the apparent clearance (CL/F) of atorvastatin through population pharmacokinetic (PopPK) modeling with samples collected in a real‐life setting in
Externí odkaz:
https://doaj.org/article/3e74fcb644e746a7b4cefd7b2d602aaf
Autor:
Gabriel Stillemans, Happy Phanio Djokoto, Kévin-Alexandre Delongie, Halima El-Hamdaoui, Nadtha Panin, Vincent Haufroid, Laure Elens
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract The intracellular penetration of darunavir, a second-generation HIV protease inhibitor, is limited by the activity of the efflux P-glycoprotein (ABCB1). ABCB1 expression and/or activity levels can vary between individuals due to genetic poly
Externí odkaz:
https://doaj.org/article/a78aedce85a04099871be76d5f19ff7d
Autor:
Anne-Laure Sennesael, Anne-Sophie Larock, Jonathan Douxfils, Laure Elens, Gabriel Stillemans, Martin Wiesen, Max Taubert, Jean-Michel Dogné, Anne Spinewine, François Mullier
Publikováno v:
Thrombosis Journal, Vol 16, Iss 1, Pp 1-8 (2018)
Abstract Background Serious bleeding events have been frequently described in patients taking direct oral anticoagulants (DOAC). In secondary analyses of phase 3 trials, DOAC plasma concentrations were shown to correlate with bleeding outcomes. This
Externí odkaz:
https://doaj.org/article/1dc494086d60476894f7941f489d98be
Autor:
Nadtha Panin, Gabriel Stillemans, Halima El-Hamdaoui, Laure Elens, Kévin-Alexandre Delongie, Happy Phanio Djokoto, Vincent Haufroid
Publikováno v:
Scientific Reports, Vol. 11, no. 1, p. 9000 [1-7] (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
The intracellular penetration of darunavir, a second-generation HIV protease inhibitor, is limited by the activity of the efflux P-glycoprotein (ABCB1). ABCB1 expression and/or activity levels can vary between individuals due to genetic polymorphisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1267ff9abc1784d9d3847f02c07b16a5
https://doi.org/10.1038/s41598-021-88365-7
https://doi.org/10.1038/s41598-021-88365-7
Autor:
Leila Belkhir, Gabriel Stillemans, Laure Elens, Anne Vincent, Bernard Vandercam, Vincent Haufroid
Publikováno v:
European Journal of Clinical Pharmacology, Vol. 77, no. 4, p. 607-616 (2021)
European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology
Purpose A variety of diagnostic methods are available to validate the performance of population pharmacokinetic models. Internal validation, which applies these methods to the model building dataset and to additional data generated through Monte Carl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e584ab1c6ea3e862bb1e8192007101
https://hdl.handle.net/2078.1/240937
https://hdl.handle.net/2078.1/240937
Autor:
Gabriel Stillemans, Laure Elens, Vincent Haufroid, Leila Belkhir, Anne Vincent, Bernard Vandercam
Publikováno v:
Clinical Pharmacokinetics, Vol. 60, no. 2, p. 177-189 (2021)
Clinical Pharmacokinetics
Clinical Pharmacokinetics
Background and objectives Protease inhibitors such as darunavir are an important therapeutic option in the anti-human immunodeficiency virus arsenal. Current dosage guidelines recommend using cobicistat- or ritonavir-boosted darunavir 800 mg every 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ebbf3242d600cf028e77a3d37a4f29
https://hdl.handle.net/2078.1/231312
https://hdl.handle.net/2078.1/231312
Autor:
Nadtha Panin, Adrien Paquot, Jean-Luc Balligand, Vincent Haufroid, Emilia Hoste, Anders Åsberg, Giulio G. Muccioli, Gabriel Stillemans, Laure Elens
The purpose of this study was to investigate the potential clinical relevance of estimating the apparent clearance (CL/F) of atorvastatin through population pharmacokinetic (PopPK) modeling with samples collected in a real-life setting in a cohort of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819b058dabcef47cf9174700f2aa4322
http://hdl.handle.net/10852/92488
http://hdl.handle.net/10852/92488